Results 31 to 40 of about 592,211 (297)

Idiopathic non-histaminergic acquired angioedema: a case series and discussion of published clinical trials

Clinical and Translational Allergy, 2017
Background Idiopathic non-histaminergic acquired angioedema (InH-AAE) is a rare disease for which there are no available laboratory parameters to clearly define the disorder. Therapy is often difficult and various treatment options have been proposed. In
Martin Christian Bucher, Tatjana Petkovic, Arthur Helbling, Urs Christian Steiner   +3 more
doaj   +1 more source

Viewpoint on handling anti-TNF failure in psoriasis [PDF]

, 2013
An association among the occurrence of antidrug antibodies (ADAs), diminished trough serum drug levels (TSDLs) and non-response or loss of response has been described for several tumor necrosis factor alpha (TNF) blocking agents in a variety of diseases,
BRACKE, STEFANIE, Lambert, Jo
core   +1 more source

Rapid recovery of postnivolumab vemurafenib-induced Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) syndrome after tocilizumab and infliximab administration [PDF]

, 2020
Background Immune checkpoint inhibitors such as nivolumab and targeted BRAF inhibitors have dramatically altered the treatment outcomes of metastatic melanoma over the past few years. Skin toxicity is the most common adverse event (AE) related to the
Maestro, Alessandra, Marcuzzi, Annalisa, Maximova, Natalia, Zanon, Davide   +3 more
core   +1 more source

Production Research and Risk Factor Analysis of Transfusion and Infusion Warmer Based on Real-World Data

Zhongguo yiliao qixie zazhi
Objective To investigate the transfusion and infusion warmer manufacturers, combine the use failures to analyze adverse events, and provide support for enterprise risk management and clinical safe use.
Hongfeng BI, Yonggang WANG, Zhendong WANG, Yuan FU, Huifang NIU   +4 more
doaj   +1 more source

Association between HLA-B Alleles and Carbamazepine-Induced Maculopapular Exanthema and Severe Cutaneous Reactions in Thai Patients

Journal of Immunology Research, 2018
The HLA-B∗15:02 allele has been reported to have a strong association with carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) in Thai patients.
Chonlaphat Sukasem, Chonlawat Chaichan, Thapanat Nakkrut, Patompong Satapornpong, Kanoot Jaruthamsophon, Thawinee Jantararoungtong, Napatrupron Koomdee, Suthida Sririttha, Sadeep Medhasi, Sarawut Oo-Puthinan, Ticha Rerkpattanapipat, Jettanong Klaewsongkram, Pawinee Rerknimitr, Papapit Tuchinda, Leena Chularojanamontri, Napatra Tovanabutra, Apichaya Puangpetch, Wichai Aekplakorn   +17 more
doaj   +1 more source

Irisin Is Controlled by Farnesoid X Receptor and Regulates Cholesterol Homeostasis

Frontiers in Pharmacology, 2019
ObjectiveThe aim of this study was to investigate whether the nuclear receptor farnesoid X receptor (FXR) could regulate FNDC5/Irisin expression and the role of Irisin in hyperlipidemia and atherosclerosis in ApoE-/- mice.Methods and ResultsWe treated ...
Hong Li, Hong Li, Jing Shen, Jing Shen, Tong Wu, Tong Wu, Jiangying Kuang, Jiangying Kuang, Qinhui Liu, Shihai Cheng, Shihai Cheng, Shiyun Pu, Shiyun Pu, Lei Chen, Lei Chen, Rui Li, Rui Li, Yanping Li, Yanping Li, Min Zou, Zhiyong Zhang, Wei Jiang, Aijuan Qu, Jinhan He, Jinhan He   +24 more
doaj   +1 more source

Severe adverse drug reactions [PDF]

Clinical Medicine, 2016
Severe cutaneous adverse reactions (SCARs) can present in a multitude of ways including Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms, and acute generalised exanthematous pustulosis. While the prognosis and therapy for these conditions may vary, it is crucial that the culprit drug is ...
Ying Xin, Teo, Sarah Anne, Walsh
openaire   +2 more sources

Development of the Liverpool Adverse Drug Reaction Avoidability Assessment Tool [PDF]

, 2017
Aim To develop and test a new tool to assess the avoidability of adverse drug reactions that is suitable for use in paediatrics but which is also applicable to a variety of other settings. Methods The study involved multiple phases.
Anthony J. Nunn, D Altman, EC Davies, EJ Conroy, GT Schumock, H Dormann, H Lövborg, J Hallas, J Le, Jamie J. Kirkham, Janine Arnott, JL Fleiss, KM Hakkarainen, KM Hakkarainen, Louise E. Bracken, Mark A. Turner, Matthew Peak, MC Brouwers, Munir Pirmohamed, P Olivier, PJ McDonnell, R Smyth, RE Ferner, RM Gallagher, RM Gallagher, RMD Smyth, Rosalind L. Smyth, S Thiesen, Zheng Li   +28 more
core   +3 more sources

SIAIP position paper: provocation challenge to antibiotics and non-steroidal anti-inflammatory drugs in children [PDF]

, 2018
Drug hypersensitivity reactions (DHRs) in childhood are mainly caused by betalactam or non-betalactam antibiotics, and non-steroidal anti-inflammatory drugs (NSAIDs).
Arasi, Stefania, Barni, Simona, Bottau, Paolo, Caffarelli, Carlo, Caimmi, Davide, Caimmi, Silvia, Cardinale, Fabio, Comberiati, Pasquale, Crisafulli, SEBASTIANO GIUSEPPE, Di Mauro, Dora, Diaferio, Lucia, Duse, Marzia, Franceschini, Fabrizio, Liotti, Lucia, Marseglia, Gianluigi, Mastrorilli, Carla, Mori, Francesca, Paravati, Francesco, Pelosi, Umberto, Saretta, Francesca   +19 more
core   +1 more source

Adverse drug reactions associated with amitriptyline - protocol for a systematic multiple-indication review and meta-analysis [PDF]

, 2020
Background: Unwanted anticholinergic effects are both underestimated and frequently overlooked. Failure to identify adverse drug reactions (ADRs) can lead to prescribing cascades and the unnecessary use of over-thecounter products.
Brueckle, Maria-Sophie, Gerlach, Ferdinand M, Glasziou, Paul P, Gonzalez-Gonzalez, Ana Isabel, Harder, Sebastian, Muth, Christiane, Nguyen, Truc Sophia, Pilz, Maximilian, Seide, Svenja E, Thomas, Elizabeth T   +9 more
core   +1 more source