Results 71 to 80 of about 15,484,713 (310)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Clinical safety issues of measles, mumps and rubella vaccines
Bulletin of the World Health Organization, 2000 The clinical safety of measles and measles-mumps-rubella vaccines has been questioned in recent reports that propose a possible link between measles virus or measles vaccines and the occurrence of juvenile Crohn disease and autism.
M.A. Afzal, P.D. Minor, G.C. Schild
doaj
Reversible cycloplegia caused by duloxetine: a case report
Psychiatry and Clinical Psychopharmacology, 2017 A Duloxetine is a balanced and potent dual reuptake inhibitor of serotonin and norepinephrine (SNRI) that has previously been shown to be effective in the treatment of major depressive disorder (MDD), generalized anxiety disorder, and diabetic peripheral
Rabia Nazik Yüksel +2 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Skin reactions probably attributed to the use of phenytoin and vancomycin [PDF]
Einstein (São Paulo), 2008 Cutaneous reactions are the most common adverse events attributed to medications. Stevens-Johnson syndrome or erythema multiforme is a severe and acute reaction determined by medications, especially aspirin, phenytoin, and vancomycin.
Carla Tozato +2 more
doaj
Cannabidiol Adverse Effects and Toxicity
Current Neuropharmacology, 2019 Background: Currently, there is a great interest in the potential medical use of cannabidiol (CBD), a non-intoxicating cannabinoid. Productive pharmacological research on CBD occurred in the 1970s and intensified recently with many discoveries about the ...
M. Huestis +5 more
semanticscholar +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Ever-Present Adverse Effects [PDF]
CNS Spectrums, 2004 With our emphasis on treatment-refractory depression, one cannot help but think about recent media coverage and regulatory events surrounding antide-pressant therapy. The current debate about the safety of antidepressant therapy for children and adolescents stands out in particular.Recently, a pediatrician attending a symposium at the University of ...
openaire +2 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
A Rare Case of Inflammatory Myositis Post-intramuscular Injections of Onabotulinum Toxin
Indian Journal of Physical Medicine & RehabilitationWe describe the case of a 70-year-old male sustained a traumatic right-sided sub-dural haemorrhage and underwent decompressive craniotomy for the same.
A Aakhil Nabuhan +3 more
doaj +1 more source