Results 51 to 60 of about 54,472 (238)

Asociación de Estados del Caribe

Internaciones, 2020
El presente trabajo hace una revisión de la AEC (Asociación de Estados del Caribe) como Sistema de integración regional, sus antecedentes, proceso histórico, etapas por las que ha transitados, acuerdos y tratados resultantes, sus cuatro dimensiones base ...
César Alejandro Guzmán Ulloa, Christian Iván Sánchez   +1 more
doaj   +1 more source

Methodology for BIM implementation in the Kingdom of Saudi Arabia [PDF]

International Journal of BIM and Engineering Science, 2019
Purpose – The Architecture, Engineering, and Construction (AEC) industry is considered the most effective contributor to development in the Kingdom of Saudi Arabia (KSA).
Ashraf Elhendawi, Andrew Smith, Emad Elbeltagi   +2 more
doaj   +1 more source

Tracking CDK1 Dynamics With a Novel Biosensor Mouse and Clinical Cohorts to Predict CDK4/6 Inhibitor Sensitivity in ER+ Breast Cancer

Advanced Science, EarlyView.
Cyclin‐dependent kinase (CDK) 1 activity is a dynamic marker of treatment response in estrogen receptor positive breast cancer. Patient cohorts reveal CDK1 activity increases during progression to invasive disease, where high expression correlates with poor survival. Using a novel Cdk1 biosensor mouse alongside in vitro models, we demonstrate that CDK1
Sarah Alexandrou, Kristine J. Fernandez, Min Li Huang, Ewan K. A. Millar, Claire Vennin, Leila Eshraghi, Tan Dat Timothy Lam, Victoria Lee, Nyah C. Brooks, Janett Stoehr, Cristian Guaman Mendez, Douglas Strathdee, David Stevenson, David Herrmann, Sandra O'Toole, Paul Timpson, Max Nobis, C. Elizabeth Caldon   +17 more
wiley   +1 more source

Practical Approach for Paving the Way to Motivate BIM Non-users to Adopt BIM [PDF]

International Journal of BIM and Engineering Science, 2019
Typically, the Architecture, Engineering, and Construction (AEC) industry is considered one of the most effective contributor to the national developments worldwide.
Ashraf Elhendawi, Hany Omar, Emad Elbeltagi, Andrew Smith   +3 more
doaj   +1 more source

AEC industry culture: a need for change [PDF]

, 2004
Future development in determining new and improved ways for Architectural, Engineering, and Contractor (AEC) industry participants to do business through information and communication technology (ICT) tools and systems is dependent on the innovation of ...
Weippert, Achim, Kajewski, Stephen L.
core   +1 more source

Determination of Gene‐Level Fitness Contributions Across the Mucin‐Utilization Network of Bacteroides thetaiotaomicron

Advanced Science, EarlyView.
Genome‐wide CRISPRi and RNA‐seq resolve how B. thetaiotaomicron converts host mucosal glycans into fitness. The study reveals a layered mucin‐utilization architecture in which capsular polysaccharides constrain surface access, extracellular CAZymes and peptidases show functional redundancy, and intracellular catabolic pathways create discrete metabolic
Kangsan Kim, Jiwon Lee, Minjeong Kang, Sung Sun Yim, Donghui Choe, Byung‐Kwan Cho   +5 more
wiley   +1 more source

Challenges Facing the Implementation of Building Information Modeling (BIM) Techniques in Iraq.

Zanco Journal of Pure and Applied Sciences, 2020
Building Information Modeling (BIM) technology is a modern technology in the construction industry that has seen widespread and implementation in construction projects around the world in recent years.
Mahmood Maad Mahdi, Dana Khider Mawlood
doaj   +1 more source

Thioredoxin‐2 Alleviates Osteoporosis by Restraining FOXO3a Nuclear Translocation

Advanced Science, EarlyView.
Endothelial TRX2 preserves bone homeostasis by retaining FOXO3a at mitochondria and limiting TRAIL production. Loss of TRX2 or oxidative stress releases FOXO3a for nuclear translocation, increasing endothelial TRAIL secretion and driving osteoclast formation and bone loss.
Chi Zhan, Zhaocai Zhou, Yue Ding, Rong Lian, Xinyu Li, Xintong Zhang, Jie Cao, Zhonghui Tang, Zhengmei Lin, Zhi Song, Feng He   +10 more
wiley   +1 more source

การรับรู้เกี่ยวกับการเข้าสู่ประชาคมเศรษฐกิจอาเซียน (AEC) ของบุคลากรสำนักงบประมาณ [PDF]

, 2021
วิทยานิพนธ์ (บธ.ม.) -- มหาวิทยาลัยเทคโนโลยีราชมงคลพระนคร, 2559The purpose is to study the level of knowledge and understanding about AEC reviews and availability towards the ASEAN Economic Community (AEC) of the personnel budget.
สุรเชษฐ์ เหล็งขยัน, Lengkhayan, Surachet   +1 more
core  

BRCA1 Mutation‐Recognizing Tetrahedral Framework Nucleic Acid Nanoplatform Enables Coordinated PARP/WEE1 Inhibition and STING‐Associated Antitumor Immunity in Ovarian Cancer

Advanced Science, EarlyView.
BRCA1 mutation‐responsive FBOA‐tFNA selectively recognizes mutant transcripts and coordinates reduction‐responsive intracellular delivery of olaparib and adavosertib, amplifying DNA damage and weakening G2/M checkpoint protection. These effects are accompanied by STING‐associated immune activation and stronger antitumor immunity, while sequential anti ...
Chenyi Wang, Mengying Yao, Jinhui Xie, Dingjie Wang, Yashi Shi, Xiaodan Mao, Chunhua Lu, Pengming Sun   +7 more
wiley   +1 more source