Results 91 to 100 of about 42,465 (263)

Lactate Signal: Modulator of Cellular Energy Production and Anabolism

Advanced Science, EarlyView.
Compartmentalized lactate signaling provides a spatial framework for understanding how lactate‐rich states are generated, transported, sensed, and translated into biological outputs. This Review integrates extracellular, cytosolic, mitochondrial‐associated, and nuclear lactate mechanisms to explain how lactate shapes metabolic adaptation, immune ...
Han Wang, Si‐Yuan Yang, Wei Xu
wiley   +1 more source

PDHA1 Hyperactivation‐Mediated Glucose Metabolism Reprogramming Fuels Neutrophil NETosis and Promotes Acute Lung Injury

Advanced Science, EarlyView.
During NETosis, neutrophils shift metabolically toward enhanced OXPHOS and partially reduced glycolysis. This shift is driven by PDHA1 hyperactivity‐dependent selective metabolic reprogramming. The neutrophil‐targeted nanoparticle 3‑FP‑BSA NPs effectively inhibit NETosis and attenuate ALI.
Yu‐Biao Liu, Wen‐Jing Zhong, Chen‐Yu Zhang, Meng‐Rui Chen, Nan‐Shi‐Yu Yang, Han‐Xi Sha, Yan‐Ling Qiu, Hui Chen, Jin‐Tong Yang, Li‐Ying Liang, Jian‐Bing Xiong, Shao‐Kun Liu, Cha‐Xiang Guan, Jia‐Xi Duan, Yong Zhou   +14 more
wiley   +1 more source

Abdominal aerobic endurance exercise reveals spot reduction exists: A randomized controlled trial. [PDF]

Physiol Rep, 2023
Brobakken MF, Krogsaeter I, Helgerud J, Wang E, Hoff J.   +4 more
europepmc   +1 more source

THE EFFECT OF ANAEROBIC AND AEROBIC EXERCISE ON ENDURANCE AND NON ENDURANCE ATHLETES ON PREMENSTRUAL SYNDROME (PMS)

IOP Conference Series: Materials Science and Engineering, 2017
Premenstrual syndrome (PMS) is a symptom of discomfort that could happen 7-10 days before menstruation. This symptoms can be affect physiologically and psychologically. The purpose of this research is to investigate the influence of anaerobic and aerobic exercise in endurance and non endurance female athletes in related to the symptoms of premenstrual ...
openaire   +2 more sources

The Characteristics of Tumor Microenvironment by the Single Cell Profile in Endometrial Cancer of no Specific Molecular Profile (NSMP) Subtype

Advanced Science, EarlyView.
A subset of tumor‐associated macrophages (TAMs) characterized by SPP1 expression is discovered, which may remodel the tumor microenvironment by potentially promoting CD4+ T cell stress and maintaining epithelial cell stemness through SPP1‐CD44, thereby potentially contributing to the proliferation and migration of tumor cells, which has been verified ...
Xinhui Yuan, Zhengyao Zhai, Chuyu Jing, Wei Zhang, Wenjuan Tian, Yulan Ren   +5 more
wiley   +1 more source

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

Hepatology, EarlyView., 2022
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso, Tawhidul Islam, Julie Magusto, Ricardo Amorim, Véronique Lenoir, Rui F. Simões, José Teixeira, Liana C. Silva, Dominique Wendum, Isabelle Jéru, Corinne Vigouroux, Rui E. Castro, Paulo J. Oliveira, Carina Prip‐Buus, Vlad Ratziu, Jérémie Gautheron, Cecília M. P. Rodrigues   +16 more
wiley   +1 more source

Polyphosphate Copper Nanospheres Drive Mitochondrial Metabolic Reprogramming via Calcium Phase Separation for Self‐Sensitizing Cuproptosis

Advanced Science, EarlyView.
This study developed polyphosphate (polyP)‐based nanostructures that enable calcium‐mediated metabolic reprogramming via liquid–liquid phase separation (LLPS). Released polyP undergoes LLPS with Ca2+, suppressing glycolytic flux and enhancing mitochondrial metabolism effectively.
Jing Wang, Xinyang Zhao, Zifeng Huang, Jingyi Zhang, Yucheng Tao, Yong Huang, Zijian Guo, Lei Dong, Xiuxiu Wang, Jing Zhao, Wei Wei   +10 more
wiley   +1 more source

The effects of short‐term consumption of a Western diet on aerobic exercise performance in bank voles with inherently distinct metabolic rates

Experimental Physiology
Because obesity and related diseases are partly attributed to unrestricted consumption of a high‐fat, high‐sugar Western diet (WD), several studies have examined its adverse effects on health and physical fitness.
Alaa Hseiky, Edyta T. Sadowska, Paweł Koteja   +2 more
doaj   +1 more source

The Impact of Targeted Soccer Training Interventions on YO–YO Intermittent Recovery Test Performance in University-Level Soccer Players

Physical Education Theory and Methodology
Background. Soccer demands high endurance, speed, and aerobic capacity, making fitness a key performance factor. The Yo-Yo Intermittent Recovery Test Level 1 (YYIR1) is a valid field test to assess these attributes in soccer players. Objectives.
Gopal Chandra Saha, Chandan Shaw, Bekir Erhan Orhan, Prem Kumar Karak, Smriti Mondal, Shantanu Halder, Subhashis Biswas, Bidya Roy   +7 more
doaj   +1 more source

Effects of acute exercise on memory: Considerations of exercise intensity, post-exercise recovery period and aerobic endurance. [PDF]

Mem Cognit, 2023
Loprinzi PD, Roig M, Tomporowski PD, Javadi AH, Kelemen WL.   +4 more
europepmc   +1 more source