Results 101 to 110 of about 111,400 (297)

Designer Dynamic DNA Nanoaggregate in Living Cell for Mitochondrial Energy Restriction

Advanced Science, EarlyView.
This study presents the Tech‐tetrahedron, a designer dynamic DNA nanoaggregate engineered for precise mitochondrial energy restriction. Its trinity‐functionalized design integrates navigable unit, telomerase‐activated latch, and self‐assembly module.
Ruijia Deng, Jing Sheng, Ben Niu, Wenjuan Fu, Yingjie Yang, Zuowei Xie, Shuang Xie, Yunxuan He, Meilin Gong, Jue Wang, Yan Pi, Ming Chen, Kai Chang   +12 more
wiley   +1 more source

An efficient and scalable room temperature aerobic oxidation catalyzed by iron chloride hexahydratemesoporous silicaalcohol supported TEMPO

, 2013
An efficient and scalable room temperature aerobic oxidation catalyzed by iron chloride hexahydratemesoporous silicaalcohol supported ...
李军, 吕迎, 王连月, 高爽, 张恒耘, Xiaoping Zhao   +5 more
core  

Astrocytic FDX1 Contributes to Copper Dyshomeostasis‐associated Synaptic Dysfunction in Depression and Is Modulated by Exercise

Advanced Science, EarlyView.
Chronic stress disrupts copper homeostasis and promotes copper accumulation in the prelimbic cortex, leading to astrocytic FDX1 upregulation. Elevated astrocytic FDX1 impairs calcium signaling, induces structural atrophy, and disrupts synaptic function, contributing to depressive‐like behaviors. Physical exercise reverses these alterations by restoring
Lina Gao, Rongji Hui, Zhibo Tang, Tao Feng, Zhihang Hu, Xiaoqing Zhang, Ping Jiang, Hui Zhao, Kwok‐Fai So, Tianyuan Luo, Yanzhou Chang, Lan Yan   +11 more
wiley   +1 more source

Spatiotemporal Targeting Randle Cycle and Immune Checkpoint for Potent Antitumor Therapy

Advanced Science, EarlyView.
A glucose oxidase‐based nanogel (GOX‐NG) system using catechol‐functionalized alginate, exhibits enhanced tumor penetration, prolonged retention, and sustained glucose depletion in the tumor microenvironment. When combined with a fatty acid oxidation inhibitor, it implements dual metabolic suppression, thereby enhancing ROS‐induced immunogenic cell ...
Yuan Gao, Zijian Gong, Yixuan Fu, Jianan Zheng, Xiao Sang, Binglin Chen, Qinzhi Su, Weiping Gao, Fei Duan, Jinqi Wei, Xuliang Deng, Xinyu Liu   +11 more
wiley   +1 more source

Oxidation of Benzyl Alcohols to Carbonyl Compounds Catalyzed by Reusable Manganese Porphyrin under Mild Aqueous Conditions [PDF]

Iranian Journal of Chemistry & Chemical Engineering
The main aim of this study is to introduce a new catalytic system referred to as p(NaAMPS-co-AN)‐[Mn(TMPyP)], which is a combination of poly[(2‐acrylamido-2-methyl-1-propane sulfonic acid-co-acrylonitrile)-Mn(III) meso tetra(N-methyl-4-pyridyl) porphine.
Zahra Sokhandan, Massomeh Ghorbanloo, Tahereh Mokary Yazdely   +2 more
doaj   +1 more source

Microbial oxidation of arsenite in a subarctic environment: diversity of arsenite oxidase genes and identification of a psychrotolerant arsenite oxidiser [PDF]

, 2010
Background Arsenic is toxic to most living cells. The two soluble inorganic forms of arsenic are arsenite (+3) and arsenate (+5), with arsenite the more toxic.
Hudson-Edwards, KA, Osborne Thomas H, Osborne, T.H., Hudson-Edwards, Karen A., Walker, Stephen R., Osborne, Thomas H., Stephen R Walker, Hudson-Edwards Karen A, Joanne M Santini, Santini, JM, Ward, S.A., Jamieson, H.E., Thomas H Osborne, Nordstrom, DK, Nordstrom, K., Nordstrom, D. Kirk, Jamieson, HE, Walker, S.R., Santini, J.M., Ward, Seamus A., Ward Seamus A, Jamieson, Heather E., Osborne, TH, Osborne, Tom, Heather E Jamieson, Jamieson Heather E, Santini, Joanne M., Karen A Hudson-Edwards, Seamus A Ward, Walker Stephen R, Walker, SR, D Kirk Nordstrom, Nordstrom D Kirk, Santini Joanne M, Ward, SA   +34 more
core   +1 more source

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

Advanced Science, EarlyView.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang, Shaofang He, Zhongkai Wang, Aobo Pang, Xiaoli Sun, Rongchen Liu, Fang Wang, Sisi Chen, Zhijuan Bian, Dongcheng Wei, Liuhan Wu, Siyao Zhao, Qiuting Ji, Yiqi Sun, Niying Sun, Yushinta Fujaya, Boping Tang, Kianann Tan, Daizhen Zhang, Lianfu Chen   +19 more
wiley   +1 more source

Self-assembly of an Organometallic Fe9O6 Cluster from Aerobic Oxidation of (tmeda)Fe(CH2tBu)2

, 2019
Substoichiometric aerobic oxidation of the high-spin organometallic compound (tmeda)Fe(CH2tBu)2 (tmeda = N,N,N’,N’- tetramethylethylenediamine) in toluene or THF solution leads to the self-assembly of a magic-sized all-ferrous oxide cluster containing ...
Matthew P., Shores, V. Codrina, Popescu, Elliott, Hulley, Zachary, Hecht, Navamoney, Arulsamy, Brooke N., Livesay, Jonathan, Kephart   +6 more
core   +1 more source

Tumor Microenvironment‐Responsive Nanoreactor Induces Disulfidptosis in Pancreatic Cancer via Metabolic Interference and Redox Catalysis

Advanced Science, EarlyView.
Schematic illustration of a tumor microenvironment‐responsive nanoreactor for imaging‐guided induction of disulfidptosis in pancreatic cancer via metabolic interference and redox catalysis. (A) Stepwise fabrication of Pht@HMnO2‐HA, including MnO2 growth on a SiO2 template, template removal to form hollow mesoporous MnO2, Pht loading, and subsequent ...
Rui Fu, Qing Li, Guanzhong Zhao, Qingyan Gao, Huantong Chen, Khemayanto Hidayat, Jiaying Xu, Liqiang Qin, Chunhong Hu, Yu Chong, Su Hu   +10 more
wiley   +1 more source

Pd/C-catalyzed aerobic oxidative esterification of alcohols and aldehydes: a highly efficient microwave-assisted green protocol

Beilstein Journal of Organic Chemistry, 2014
We herein describe an environmentally friendly microwave-assisted oxidative esterification of alcohols and aldehydes in the presence of molecular oxygen and a heterogeneous catalysis (Pd/C, 5 mol %). This efficient and ligandless conversion procedure does
Marina Caporaso, Giancarlo Cravotto, Spyros Georgakopoulos, George Heropoulos, Katia Martina, Silvia Tagliapietra   +5 more
doaj   +1 more source