Results 101 to 110 of about 12,489,898 (339)
Multidisciplinary Aerodynamic Design of a Rotor Blade for an Optimum Rotor Speed Helicopter
, 2017 The aerodynamic design of rotor blades is challenging, and is crucial for the development of helicopter technology. Previous aerodynamic optimizations that focused only on limited design points find it difficult to balance flight performance across the ...
Jiayi Xie +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
The aerodynamic challenges of the design and development of the space shuttle orbiter [PDF]
The major aerodynamic design challenge at the beginning of the United States Space Transportation System (STS) research and development phase was to design a vehicle that would fly as a spacecraft during early entry and as an aircraft during the final ...
Gamble, J. D. +9 more
core +1 more source
Forward bearing reactor mechanism for Titan 3-E/Centaur D-1T space launch vehicle [PDF]
, 1975 System between the Titan/Centaur launch vehicle and its aerodynamic shroud is described. The system provides a precise spring constant and is capable of being inactivated during flight.
Jones, R. A.
core +1 more source
A New Cokriging Method for Variable-Fidelity Surrogate Modeling of Aerodynamic Data [PDF]
, 2010 Cokriging is a statistical interpolation method for the enhanced prediction of a less intensively sampled primary variable of interest with assistance of intensively sampled auxiliary variables. In the geostatistics community it is referred to as two- or
Görtz, Stefan +2 more
core +1 more source
Aerodynamic design of horizontal axis wind turbine blades
, 2017 Designing horizontal axis wind turbine (HAWT) blades to achieve satisfactory levels of performance starts with the knowledge of aerodynamic forces acting on the blades.
Biadgo Asress Mulugeta +1 more
semanticscholar +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Aerodynamic design using numerical optimization [PDF]
The procedure of using numerical optimization methods coupled with computational fluid dynamic (CFD) codes for the development of an aerodynamic design is examined.
Chapman, G. T., Murman, E. M.
core +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source