Results 31 to 40 of about 12,726 (261)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Wind Turbine Enhancement via Active Flow Control Implementation
Applied SciencesThe present research enhances the efficiency of an airfoil section from the DTU-10MW Horizontal Axis Wind Turbine (HAWT) via Active Flow Control (AFC) implementation and when using synthetic jets (SJ).
Marc Lahoz +3 more
doaj +1 more source
Effects of low and high frequency actuation on aerodynamic performance of a supercritical airfoil
Frontiers in Mechanical Engineering, 2023 The main objective of this study is to investigate the effects of low and high frequency actuation in improving the aerodynamic performance of the supercritical airfoil with the approach of using it in a high-lift or flight control device.
Soheila Abdolahipour
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
A study on aerodynamics of Ultra-efficient cars
Journal of Physics: Conference Series, 2023 Abstract Ultra-efficient cars (i.e. Formula One racing cars) are loaded with many different aerodynamic components. They interact to produce highly nonlinear flows, which have a very complex effect on the airflow around the racing car. Clearing up fluid phenomena makes it possible to optimize aerodynamic components effectively.
openaire +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Energy Science & EngineeringThe increasing demand for energy in daily life and the finite nature of fossil fuel reserves have driven researchers worldwide to explore renewable energy sources such as wind energy.
Reza Abbaspour +2 more
doaj +1 more source
Drvna Industrija, 2016 This paper introduces a numerical methodology based on a 3D turbulent flow computation developed to assess the aerodynamic performances of lumber drying kilns.
Bogdan Bedelean +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source