Results 41 to 50 of about 12,726 (261)

Aerodynamic Optimization Design of a Multistage Centrifugal Steam Turbine and Its Off-Design Performance Analysis

open access: yesInternational Journal of Rotating Machinery, 2017
Centrifugal turbine which has less land occupation, simple structure, and high aerodynamic efficiency is suitable to be used as small to medium size steam turbines or waste heat recovery plant.
Hui Li, Dian-Gui Huang
doaj   +1 more source

Flow Control in Wings and Discovery of Novel Approaches via Deep Reinforcement Learning

open access: yesFluids, 2022
In this review, we summarize existing trends of flow control used to improve the aerodynamic efficiency of wings. We first discuss active methods to control turbulence, starting with flat-plate geometries and building towards the more complicated flow ...
Ricardo Vinuesa   +3 more
doaj   +1 more source

Dynamic stability of an aerodynamically efficient motorcycle

open access: yesVehicle System Dynamics, 2012
Motorcycles exhibit two potentially dangerous oscillatory modes known as ‘wobble’ and ‘weave’. The former is reminiscent of supermarket castor shimmy, while the latter is a low frequency ‘fish-tailing’ motion that involves a combination of rolling, yawing, steering and side-slipping motions.
Sharma, A, Limebeer, D
openaire   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Numerical simulation of unsteady aerodynamic characteristics of the three-dimensional composite motion of a flapping wing based on overlapping nested grids

open access: yesAIP Advances, 2020
Numerical simulations of the unsteady aerodynamic characteristics of the flapping wing composite motion are performed. To avoid negative grid sizes arising with the use of a dynamic grid and leading to divergences in the simulation and to errors in the ...
Lun Li   +4 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

PERFORMANCE OF 3D PRINTED CONVENTIONAL AND TOROIDAL PROPELLER FOR SMALL MULTIROTOR DRONES

open access: yesJournal of Industrial Design and Engineering Graphics, 2023
This paper presents a study on the design, fabrication, and performance evaluation of a quadcopter with toroidal propellers manufactured using 3D printing technology.
Gabriel ION, Ionel SIMION
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

The Effect of Airfoil Geometry Variation on the Efficiency of a Small Wind Turbine

open access: yesTechnologies
This study analyzes the impact of geometric variations induced by the manufacturing process on the aerodynamic efficiency of an airfoil used in the design of a 3 kW wind turbine blade.
José Rafael Dorrego Portela   +7 more
doaj   +1 more source

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