Results 71 to 80 of about 90,246 (309)

Aerodynamic ground effect in fruitfly sized insect takeoff [PDF]

, 2016
Aerodynamic ground effect in flapping-wing insect flight is of importance to comparative morphologies and of interest to the micro-air-vehicle (MAV) community.
ENGELS, Thomas, Gurka, Roi, Kolomenskiy, Dmitry, Liu, Hao, Maeda, Masateru, Nave, Jean-Christophe, Schneider, Kai   +6 more
core   +5 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Experimental analysis of alternative rider postures for low drag motorcycle design

Transportation Research Interdisciplinary Perspectives
The aerodynamic drag of a motorcycle greatly affects its energy efficiency, with the rider’s posture being a key factor in determining overall drag. This study presents a systematic comparative analysis of various rider postures through a multi-phase ...
Frederick Spaven, Yuanchang Liu, Mehdi Baghdadi   +2 more
doaj   +1 more source

Simulating the aerodynamic performance and wake dynamics of a vertical-axis wind turbine [PDF]

, 2011
The accurate prediction of the aerodynamics and performance of vertical-axis wind turbines is essential if their design is to be improved but poses a signifi cant challenge to numerical simulation tools.
Brown, Richard, Fletcher, Timothy M., Scheurich, Frank   +2 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Unsteady Aerodynamic Interaction Between Rotor and Ground Obstacle [PDF]

, 2018
The mutual aerodynamic interaction between rotor wake and surrounding obstacles is complex, and generates high compensatory workload for pilots, degradation of the handling qualities and performance, and unsteady force on the structure of the obstacles.
Barakos, George N., Green, Richard B., Sun, Yi Ming, Tan, Jian Feng, Zhou, Tian Yi   +4 more
core  

Numerical simulation of the airflow–rivulet interaction associated with the rain-wind induced vibration phenomenon [PDF]

, 2011
Rain-wind induced vibration is an aeroelastic phenomenon that occurs on the inclined cables of cable-stayed bridges. The vibrations are believed to be caused by a complicated nonlinear interaction between rivulets of rain water that run down the cables ...
Robertson, Andrew Colin, Taylor, Ian
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Research on Unsteady Aerodynamic Interference for the Tiltrotor Aircraft in Hover

Hangkong gongcheng jinzhan, 2019
The high resolution numerical simulation for rotor/wing-body interaction flow-field in hover is crucial for the accurate prediction of aerodynamic performance of the tilt-rotor aircraft, and is the one of the important issues of helicopter aerodynamics ...
Sun Kaijun, Zhang Bihui, Fu Yiwei, Zhang Lian   +3 more
doaj   +1 more source