Results 61 to 70 of about 147,005 (295)

ASPIRE Aerodynamic Models and Flight Performance [PDF]

AIAA Aviation 2019 Forum, 2019
The Advanced Supersonic Parachute Inflation Research Experiments (ASPIRE) project waslaunched to develop the capability for testing supersonic parachutes at Mars-relevant conditions.Three initial parachute tests, targeted as a risk-reduction activity for NASA's upcomingMars2020 mission, successfully tested two candidate parachute designs and provided ...
Suman Muppidi, Clara O'Farrell, John W. Van Norman, Ian G. Clark   +3 more
openaire   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Role of Partial Flexibility on Flow Evolution and Aerodynamic Power Efficiency over a Turbine Blade Airfoil

Aerospace
In this study, the aerodynamic performance of a cambered wind turbine airfoil with a partially flexible membrane material on its suction surface was examined experimentally across various angles of attack and Reynolds numbers.
Kemal Koca, Mustafa Serdar Genç
doaj   +1 more source

Investigation of wheelhouse shapes on the aerodynamic characteristics of a generic car model

Advances in Mechanical Engineering, 2021
As vehicle speed increases, the aerodynamic drag reduction becomes increasingly significant. The aim of this paper is to find out the effects of the wheelhouse shapes on the aerodynamics of an Ahmed body with a 35 slant angle. In this paper, based on the
Haichao Zhou, Qingyun Chen, Runzhi Qin, Lingxin Zhang, Huiyun Li   +4 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Aerodynamic Effects of Corrugation on Dragonfly Hindwing

Hangkong gongcheng jinzhan, 2019
To study aerodynamic performance of the dragonfly wing at gliding flight at different Reynolds numbers, a three-dimensional model of the dragonfly hindwing with corrugation and a three-dimensional flat plate with the same shape of the dragonfly hindwing ...
Luo Yun, He Guoyi, Wang Qi, Song Hang, Chen Donghui   +4 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Joint sensitivity analysis method of impeller aerodynamic performance to key geometric errors of five-axis machine tool

Engineering Science and Technology, an International Journal
As a high-performance workpiece, an impeller must ensure both dimensional accuracy and aerodynamic performance. A five-axis machine tool has various geometric errors, which seriously influence the impeller processing quality, hence it is crucial to ...
Hainan Zhang, Sitong Xiang, Tao Zhou, Jianguo Yang   +3 more
doaj   +1 more source

Simulation of Unsteady Aerdynamic Load for Rigid Coaxial Rotor in Forward Flight with Vortex Particle Method [PDF]

, 2017
Co-axial rotor systems are frequently used for high-speed helicopters. Nevertheless, issues related to rotor-head drag, aerodynamic performance and vibration should also be considered. Simulating the unsteady aerodynamic loads for a rigid coaxial rotor,
Barakos, George N., Sun, Yiming, Tan, Jianfeng   +2 more
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source