Results 81 to 90 of about 149,179 (315)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Investigation of wheelhouse shapes on the aerodynamic characteristics of a generic car model
Advances in Mechanical Engineering, 2021 As vehicle speed increases, the aerodynamic drag reduction becomes increasingly significant. The aim of this paper is to find out the effects of the wheelhouse shapes on the aerodynamics of an Ahmed body with a 35 slant angle. In this paper, based on the
Haichao Zhou +4 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Aerodynamic Effects of Corrugation on Dragonfly Hindwing
Hangkong gongcheng jinzhan, 2019 To study aerodynamic performance of the dragonfly wing at gliding flight at different Reynolds numbers, a three-dimensional model of the dragonfly hindwing with corrugation and a three-dimensional flat plate with the same shape of the dragonfly hindwing ...
Luo Yun +4 more
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Engineering Science and Technology, an International JournalAs a high-performance workpiece, an impeller must ensure both dimensional accuracy and aerodynamic performance. A five-axis machine tool has various geometric errors, which seriously influence the impeller processing quality, hence it is crucial to ...
Hainan Zhang +3 more
doaj +1 more source
Assessment of aerodynamic performance of V/STOL and STOVL fighter aircraft [PDF]
The aerodynamic performance of V/STOL and STOVL fighter/attack aircraft was assessed. Aerodynamic and propulsion/airframe integration activities are described and small and large scale research programs are considered. Uncertainties affecting aerodynamic
Nelms, W. P.
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Rotor blade aerodynamic design [PDF]
Aerodynamic performance aspects of rotor blade design are presented.
Noonan, Kevin W., Walsh, Joanne L.
core +1 more source
Quantification of airfoil geometry-induced aerodynamic uncertainties - comparison of approaches [PDF]
, 2016 Uncertainty quantification in aerodynamic simulations calls for efficient numerical methods since it is computationally expensive, especially for the uncertainties caused by random geometry variations which involve a large number of variables. This paper
Litvinenko, Alexander +3 more
core +2 more sources