Results 81 to 90 of about 7,144 (173)

Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine

open access: yesJournal of Extracellular Vesicles, 2018
Extracellular vesicles (EVs) have a great potential in clinical applications. However, their isolation from different bodily fluids and their characterisation are currently not optimal or standardised.
Eline Oeyen   +10 more
doaj   +1 more source

RUNX1 Is a Key Target in t(4;11) Leukemias that Contributes to Gene Activation through an AF4-MLL Complex Interaction

open access: yesCell Reports, 2013
The Mixed Lineage Leukemia (MLL) protein is an important epigenetic regulator required for the maintenance of gene activation during development. MLL chromosomal translocations produce novel fusion proteins that cause aggressive leukemias in humans ...
Adam C. Wilkinson   +11 more
doaj   +1 more source

Pathogenetic, Clinical, and Prognostic Features of Adult t(4;11)(q21;q23)/MLL-AF4 Positive B-Cell Acute Lymphoblastic Leukemia

open access: yesAdvances in Hematology, 2011
Translocation t(4;11)(q21;q23) leading to formation of MLL-AF4 fusion gene is found in about 10% of newly diagnosed B-cell acute lymphoblastic leukemia (ALL) in adult patients.
F. Marchesi, K. Girardi, G. Avvisati
doaj   +1 more source

The role of DOT1L in MLL-AF4 leukaemia

open access: yes, 2018
DOT1L is a methyltransferase which has been shown to methylate H3K79 (Ng et al. 2002; Feng et al. 2002; Lacoste et al. 2002). DOT1L and H3K79me have been shown to be involved in active transcription and in particular has been shown to be important for MLL-AF4 leukaemia, where high levels of H3K79me are found at MLL-AF4 gene targets (Krivtsov et al ...
openaire   +2 more sources

Manual Remodelling of AF4 and O2 Electrodes in Schizophrenia

open access: yesEduma : Mathematics Education Learning and Teaching, 2019
Manual recreation of AF4 and O2 electrodes in schizophrenia. This study aims to: a) Know the EEG signals in the brain in humans, b) find out how manual rearrangements of the AF4 electrode and O2 electrode in schizophrenic patients and c) find out how the interpolation method compares at the AF4 and O2 electrodes in schizophrenic patients.Rearrangement ...
Redi Gunawan, Indah Nursuprianah
openaire   +1 more source

Parâmetros genéticos para produção de leite no dia do controle de vacas da raça Holandesa utilizando modelos de análises de fatores e componentes principais

open access: yesCiência Rural, 2015
Objetivou-se comparar um modelo multi-característica padrão com modelos de análise de fatores (AF) e de componentes principais (CP) para estimar parâmetros genéticos para a produção de leite no dia do controle (PLDC) de vacas da raça Holandesa. O arquivo
Mariana de Almeida Dornelles   +8 more
doaj   +1 more source

LAF4 (lymphoid nuclear protein related to AF4) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on LAF4 (lymphoid nuclear protein related to AF4), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire   +1 more source

Venetoclax in combination with chidamide and azacitidine for the treatment of relapsed/refractory B-cell acute lymphoblastic leukemia with the MLL-AF4 gene: a case report and literature review

open access: yesFrontiers in Immunology
B-cell acute lymphoblastic leukemia (B-ALL) with the MLL-AF4 fusion gene has a poor prognosis, and the mortality rate exceeds 90%, particularly in cases of extramedullary relapse (EMR).
Xuelian Jin, Zhigang Liu, Yu Wu, Jie Ji
doaj   +1 more source

Poster Sessions

open access: yes
HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

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