Results 81 to 90 of about 7,144 (173)
Extracellular vesicles (EVs) have a great potential in clinical applications. However, their isolation from different bodily fluids and their characterisation are currently not optimal or standardised.
Eline Oeyen +10 more
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The Mixed Lineage Leukemia (MLL) protein is an important epigenetic regulator required for the maintenance of gene activation during development. MLL chromosomal translocations produce novel fusion proteins that cause aggressive leukemias in humans ...
Adam C. Wilkinson +11 more
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Translocation t(4;11)(q21;q23) leading to formation of MLL-AF4 fusion gene is found in about 10% of newly diagnosed B-cell acute lymphoblastic leukemia (ALL) in adult patients.
F. Marchesi, K. Girardi, G. Avvisati
doaj +1 more source
The role of DOT1L in MLL-AF4 leukaemia
DOT1L is a methyltransferase which has been shown to methylate H3K79 (Ng et al. 2002; Feng et al. 2002; Lacoste et al. 2002). DOT1L and H3K79me have been shown to be involved in active transcription and in particular has been shown to be important for MLL-AF4 leukaemia, where high levels of H3K79me are found at MLL-AF4 gene targets (Krivtsov et al ...
openaire +2 more sources
Manual Remodelling of AF4 and O2 Electrodes in Schizophrenia
Manual recreation of AF4 and O2 electrodes in schizophrenia. This study aims to: a) Know the EEG signals in the brain in humans, b) find out how manual rearrangements of the AF4 electrode and O2 electrode in schizophrenic patients and c) find out how the interpolation method compares at the AF4 and O2 electrodes in schizophrenic patients.Rearrangement ...
Redi Gunawan, Indah Nursuprianah
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Objetivou-se comparar um modelo multi-característica padrão com modelos de análise de fatores (AF) e de componentes principais (CP) para estimar parâmetros genéticos para a produção de leite no dia do controle (PLDC) de vacas da raça Holandesa. O arquivo
Mariana de Almeida Dornelles +8 more
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LAF4 (lymphoid nuclear protein related to AF4) [PDF]
Review on LAF4 (lymphoid nuclear protein related to AF4), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire +1 more source
B-cell acute lymphoblastic leukemia (B-ALL) with the MLL-AF4 fusion gene has a poor prognosis, and the mortality rate exceeds 90%, particularly in cases of extramedullary relapse (EMR).
Xuelian Jin, Zhigang Liu, Yu Wu, Jie Ji
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