Results 61 to 70 of about 20,267 (218)
Exploring the soliloquies of Romeo and Juliet: teacher notes (Active Shakespeare: Capturing evidence of learning) [PDF]
, 2010 Part of the 'Active Shakespeare: Capturing evidence of learning' suite of resources. "What is it about Providing active and engaging ways to integrate Shakespeare in the ongoing periodic assessment of pupils’ reading. What is it for?
core
, 2012 We study a spin-1/2 model with triangular XXZ-clusters on the orthogonal-dimer chain in the presence of an external magnetic field. First, we discuss the case where the triangular clusters are coupled via intermediate "classical" Ising spins ...
Honecker, Andreas, Ohanyan, Vadim
core +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Acute lymphoblastic leukaemia (ALL) in older adults represents a growing clinical challenge, driven by an ageing population, adverse disease biology, and reduced tolerance to intensive chemotherapy. Although pediatric‐inspired regimens have improved outcomes in younger adults with Philadelphia chromosome (Ph)‐negative ALL, survival in older ...
Antonella Bruzzese +12 more
wiley +1 more source
, 2011 Motivated by the recent discovery of Fe-based superconductors close to an antiferromagnetic insulator in the experimental phase diagram, here the five-orbital Hubbard model (without lattice distortions) is studied using the real-space Hartree-Fock ...
Dagotto, Elbio +5 more
core +1 more source
Interactive Reading Using Low Cost Brain Computer Interfaces [PDF]
, 2017 This work shows the feasibility for document reader user applications using a consumer grade non-invasive BCI headset. Although Brain Computer Interface (BCI) type devices are beginning to aim at the consumer level, the level at which they can actually ...
Hartley, Thomas +7 more
core +3 more sources
Targeting the Menin–KMT2A Axis in Acute Leukemia: From Epigenetic Dependency to Clinical Translation
European Journal of Haematology, EarlyView.ABSTRACT Acute leukemias characterized by a shared epigenetic dependency on the menin–KMT2A axis rely on aberrant HOX‐driven transcriptional programs that sustain leukemic self‐renewal and impair differentiation. This dependency is most evident in KMT2A‐rearranged and NPM1‐mutated acute myeloid leukemia (AML), but also extends to other HOX‐dependent ...
Antonella Bruzzese +12 more
wiley +1 more source
Molecules, 2023 Gastrodia elata (“Tian Ma” in Chinese) is used as a food and medical ingredient in traditional Chinese medicine. In this study, to enhance the anti-breast cancer activity of Gastrodia elata polysaccharide (GEP), GEPs were modified via sulfidation (SGEP ...
Xiaoying Liu +7 more
doaj +1 more source
The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat. [PDF]
, 2013 Human positive transcription elongation factor b (P-TEFb) phosphorylates RNA polymerase II and regulatory proteins to trigger elongation of many gene transcripts.
Alber, Tom +7 more
core +1 more source
Crosstalk between 14-3-3θ and AF4 enhances MLL-AF4 activity and promotes leukemia cell proliferation
Cellular Oncology, 2019 The t(4;11)(q21;q23) translocation characterizes a form of acute lymphoblastic leukemia with a poor prognosis. It results in a fusion gene encoding a chimeric transcription factor, MLL-AF4, that deregulates gene expression through a variety of still controversial mechanisms.
Fioretti T. +6 more
openaire +4 more sources
Understanding the Phenotypic Heterogeneity Within the Sporadic Creutzfeldt–Jakob Disease MV1 Subtype
Neuropathology and Applied Neurobiology, Volume 52, Issue 3, June 2026.We present the clinical, pathological and prion biophysical features of three atypical cases of the MV1 subtype of sporadic Creutzfeldt–Jakob disease (sCJD). We propose that these heterozygous cases exist on a spectrum ranging from MM1‐like to VV1‐like phenotypes and recommend that subtyping be performed at pH 6.9 to avoid missing atypical or mixed ...
Satish K. Nemani +6 more
wiley +1 more source