Results 61 to 70 of about 7,188 (177)

Oppositely Charged Single Enzyme Nanogels Form Versatile Coacervates for Efficient Enzyme Cascade Catalysis

Advanced Materials, Volume 38, Issue 40, 17 July 2026.
Oppositely charged single enzyme nanogels (SENs) phase‐separate into bi‐enzymatic coacervate microdroplets, acting as both scaffold and functional units. By tuning SEN ratios, these coacervates create specific microenvironments that enable selective small‐molecule enrichment and efficient intermediate diffusion.
Andoni Rodriguez‐Abetxuko, Nadia A. Erkamp, Neshat Moslehi, Yannick H. A. Leurs, Lars Paffen, Işil Yeşil Gür, Jana Stojanović, Hugo Brasselet, Laura van der Weel, Ulf Hanefeld, Ilja K. Voets, Jan C. M. van Hest   +11 more
wiley   +1 more source

Predicting Pain: Electroencephalography Signatures of Neural Integration During Experimental Tonic Thermal Pain

European Journal of Pain, Volume 30, Issue 6, July 2026.
ABSTRACT Background The identification of reliable neural signatures for pain remains a critical challenge in both clinical and experimental settings. While electroencephalography (EEG) provides a promising avenue for pain assessment, it remains unclear whether phase‐ or power‐based neural integration drives pain‐state discrimination.
Yiyuan Han, Elia Valentini, Sebastian Halder   +2 more
wiley   +1 more source

Ph‐Negative Acute Lymphoblastic Leukemia in the Older Adults: Biology, Therapeutic Strategies and Unmet Needs

European Journal of Haematology, Volume 117, Issue 1, Page 24-41, July 2026.
ABSTRACT Acute lymphoblastic leukaemia (ALL) in older adults represents a growing clinical challenge, driven by an ageing population, adverse disease biology, and reduced tolerance to intensive chemotherapy. Although pediatric‐inspired regimens have improved outcomes in younger adults with Philadelphia chromosome (Ph)‐negative ALL, survival in older ...
Antonella Bruzzese, Ernesto Vigna, Enrica Antonia Martino, Santino Caserta, Francesco Mendicino, Maria Eugenia Alvaro, Caterina Labanca, Eugenio Lucia, Virginia Olivito, Marco Fiorillo, Nicola Amodio, Fortunato Morabito, Massimo Gentile   +12 more
wiley   +1 more source

Targeting the Menin–KMT2A Axis in Acute Leukemia: From Epigenetic Dependency to Clinical Translation

European Journal of Haematology, Volume 117, Issue 1, Page 132-143, July 2026.
ABSTRACT Acute leukemias characterized by a shared epigenetic dependency on the menin–KMT2A axis rely on aberrant HOX‐driven transcriptional programs that sustain leukemic self‐renewal and impair differentiation. This dependency is most evident in KMT2A‐rearranged and NPM1‐mutated acute myeloid leukemia (AML), but also extends to other HOX‐dependent ...
Antonella Bruzzese, Ernesto Vigna, Enrica Antonia Martino, Santino Caserta, Francesco Mendicino, Maria Eugenia Alvaro, Caterina Labanca, Eugenio Lucia, Virginia Olivito, Mamdouh Skafi, Nicola Amodio, Fortunato Morabito, Massimo Gentile   +12 more
wiley   +1 more source

Supplementary Motor Area During Motor Actions in Athletes With Neurological Disorders: Observational Study of Cases and Controls

Brain and Behavior, Volume 16, Issue 6, June 2026.
Athletes with neurological disorders showed increased supplementary motor and premotor area activation during soccer‐specific motor preparation with respect to healthy controls, particularly with the affected limb, suggesting compensatory neural strategies that support motor control and performance.
Francisco Echevarría‐Lasaga, Ismael Sanz‐Esteban, Cecilia Estrada‐Barranco, Isabel Rodríguez‐Costa, Juan José García‐Hernández, José Ignacio Serrano   +5 more
wiley   +1 more source

Comparison of Miniaturized and Conventional Asymmetrical Flow Field-Flow Fractionation (AF4) Channels for Nanoparticle Separations

Separations, 2017
The performance of a miniaturized channel for the separation of polymer and metal nanoparticles (NP) using Asymmetrical Flow Field-Flow Fractionation (AF4) was investigated and compared with a conventional AF4 system.
Zengchao You, Florian Meier, Steffen Weidner   +2 more
doaj   +1 more source

Molecular-genetic methods for diagnostics of acute leukemia

Фактори експериментальної еволюції організмів, 2013
Aims. Acute leukemia - heterogeneous group of diseases characterized by the rapid growth of abnormal uncontrolled proliferation of hematopoietic stem cells or progenitor cells.
M. V. Dybkov, M. P. Zavelevich, D. F. Gluzman, L. O. Polishchuk, S. S. Maliuta, G. D. Telegeev   +5 more
doaj  

Synthesis and modification of octafluoro[2.2]paracyclophane (parylene AF4)

Organic Chemistry Frontiers, 2014
Parylenes are a class of organic compounds which have gained significant attention due to their application as coatings in areas such as medical devices and electronics. This review highlights the development of synthetic pathways to Octafluoro[2.2]Paracyclophane, commonly referred to as parylene AF4.
Hicks, Craig, Duffy, Brendan, Hargaden, Gráinne   +2 more
openaire   +4 more sources

Two promising Bacillus-derived antifungal lipopeptide leads AF4 and AF5 and their combined effect with fluconazole on the in vitro Candida glabrata biofilms

Frontiers in Pharmacology
Introduction:Candida species are endowed with the ability to produce biofilms, which is one of the causes of pathogenicity, as biofilms protect yeasts from antifungal drugs. Candida glabrata (Nakaseomyces glabrata) is one of the most prevalent pathogenic
Madduri Madhuri, Shivaprakash M. Rudramurthy, Utpal Roy   +2 more
doaj   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source