Results 51 to 60 of about 20,267 (218)

Reward processing in children with affective dysregulation

open access: yesJCPP Advances, EarlyView.
Abstract Background Affective dysregulation (AD) in children is characterized by irritability, anger, and frequent intense temper outbursts. Considerable evidence implies altered processing of frustration about missed rewards, but few studies investigated the preceding and thus potentially predictive reward anticipation and initial delivery processing ...
Pascal‐M. Aggensteiner   +11 more
wiley   +1 more source

Controlled Disassembly and Purification of Functional Viral Subassemblies Using Asymmetrical Flow Field-Flow Fractionation (AF4)

open access: yesViruses, 2018
Viruses protect their genomes by enclosing them into protein capsids that sometimes contain lipid bilayers that either reside above or below the protein layer.
Katri Eskelin, Minna M. Poranen
doaj   +1 more source

A Green Analytical Method Combined with Chemometrics for Traceability of Tomato Sauce Based on Colloidal and Volatile Fingerprinting

open access: yesMolecules, 2022
Tomato sauce is a world famous food product. Despite standards regulating the production of tomato derivatives, the market suffers frpm fraud such as product adulteration, origin mislabelling and counterfeiting.
Alessandro Zappi   +9 more
doaj   +1 more source

A DNA aptamer for binding and inhibition of DNA methyltransferase 1. [PDF]

open access: yes, 2019
DNA methyltransferases (DNMTs) are enzymes responsible for establishing and maintaining DNA methylation in cells. DNMT inhibition is actively pursued in cancer treatment, dominantly through the formation of irreversible covalent complexes between small ...
Adkins, Gary Brent   +12 more
core  

Trithorax group proteins: switching genes on and keeping them active [PDF]

open access: yes, 2011
Cellular memory is provided by two counteracting groups of chromatin proteins termed Trithorax group (TrxG) and Polycomb group (PcG) proteins. TrxG proteins activate transcription and are perhaps best known because of the involvement of the TrxG protein ...
Cavalli, G.   +3 more
core   +1 more source

Structural Profiling of Lipid Nanoparticles at Sub‐10 nm Resolution via AF4 Coupled Online to SAXS and SANS

open access: yesSmall Methods, EarlyView.
Dilution‐controlled AF4 coupled with SAXS and, for the first time, SANS enables high‐resolution characterization of non‐spherical lipid nanoparticles. Enhanced scattering contrast and D2O‐based measurements resolve particle features down to ∼5 nm and reveal shape distributions.
Eva Bittrich   +12 more
wiley   +1 more source

Rational Design and Development of Organic Afterglow Nanoparticles for Image‐Guided Interventions

open access: yesSmall Methods, EarlyView.
This review outlines the rational design, synthesis, and standardized characterization of organic afterglow nanoparticles for biomedical imaging and therapy. Mechanistic insights into chemically initiated electron exchange luminescence and reactive oxygen species‐mediated processes are connected to molecular engineering and nanoparticle fabrication ...
Asma Harun   +6 more
wiley   +1 more source

Nonstandard Higgs in Electroweak Chiral Lagrangian [PDF]

open access: yes, 2006
We add a nonstandard higgs into the traditional bosonic part of electroweak chiral Lagrangian, in purpose of finding out the contribution to EWCL coefficients from processes with internal line higgs particle.
Wang, Li-Ming, Wang, Qing
core   +2 more sources

AF4 (ALL1 fused gene from chromosome 4) - AFF1 (AF4/FMR2 family, member 1) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on AFF1 (AF4/FMR2 family, member 1), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire   +1 more source

Blocking SETD2 Enhances the Therapeutic Efficiency of Menin Inhibitor in MLL‐Fusion Leukemia

open access: yesCancer Science, EarlyView.
Combined SETD2 and menin inhibitors make synergistic effects against MLL‐fusion leukemia; the combination therapy reduces the expression of target genes through blocking transcription elongation and initiation. ABSTRACT During transcriptional elongation, the histone methyltransferase SETD2 binds to RNA polymerase II and deposits trimethylation marks at
Anpei Li   +10 more
wiley   +1 more source

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