Results 91 to 100 of about 160,044 (289)

EmoTxt: A Toolkit for Emotion Recognition from Text

open access: yes, 2017
We present EmoTxt, a toolkit for emotion recognition from text, trained and tested on a gold standard of about 9K question, answers, and comments from online interactions. We provide empirical evidence of the performance of EmoTxt.
Calefato, Fabio   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Improving classification of posture based attributed attention assessed by ranked crowd-raters

open access: yesEAI Endorsed Transactions on Pervasive Health and Technology, 2015
Attribution of attention from observable body posture is plausible, providing additional information for affective computing applications. We previously reported a promissory 69. 72 ± 10.
Patrick Heyer   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Affective Computing for Learning in Education: A Systematic Review and Bibliometric Analysis

open access: yesEducation Sciences
Affective computing is an emerging area of education research and has the potential to enhance educational outcomes. Despite the growing number of literature studies, there are still deficiencies and gaps in the domain of affective computing in education.
Rajamanickam Yuvaraj   +3 more
doaj   +1 more source

Do Embodied Conversational Agents Know When to Smile? [PDF]

open access: yes, 2002
We survey the role of humor in particular domains of human-to-human interaction with the aim of seeing whether it is useful for embodied conversational agents to integrate humor capabilities in their models of intelligence, emotions and interaction ...
Nijholt, Anton
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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