Results 111 to 120 of about 159,503 (290)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Affective computing has changed: the foundation model disruption

npj Artificial Intelligence
The dawn of Foundation Models has on the one hand revolutionised a wide range of research problems, and, on the other hand, democratised the access and use of AI-based tools by the general public.
Björn Schuller, Adria Mallol-Ragolta, Alejandro Peña Almansa, Iosif Tsangko, Mostafa M. Amin, Anastasia Semertzidou, Lukas Christ, Shahin Amiriparian   +7 more
doaj   +1 more source

AI affective computing and behavioral health

Frontiers in Computer Science
The integration of artificial intelligence (AI) and affective computing into behavioral health is transforming how mental wellbeing is assessed, monitored, and treated.
Vanessa Farsadaki, Vanessa Farsadaki, Vanessa Farsadaki, Charla Griffy-Brown   +3 more
doaj   +1 more source

Toward Emotionally Accessible Massive Open Online Courses (MOOCs) [PDF]

, 2017
This paper outlines an approach to evaluating the emotional content of three Massive Open Online Courses (MOOCs) using the affective computing approach of prosody detection on two different text-to-speech voices in conjunction with human raters judging ...
Hillaire, Garron, Iniesto, Francisco, Rienties, Bart   +2 more
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Affect and believability in game characters:a review of the use of affective computing in games [PDF]

, 2017
Virtual agents are important in many digital environments. Designing a character that highly engages users in terms of interaction is an intricate task constrained by many requirements.
ElSayed, Salma, King, David J.
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Sparsity in Dynamics of Spontaneous Subtle Emotions: Analysis \& Application

, 2016
Spontaneous subtle emotions are expressed through micro-expressions, which are tiny, sudden and short-lived dynamics of facial muscles; thus poses a great challenge for visual recognition.
Ngo, Anh Cat Le, Phan, Raphael Chung-Wei, See, John   +2 more
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Food Choices after Cognitive Load: An Affective Computing Approach. [PDF]

Sensors (Basel), 2023
Kappattanavar AM, Hecker P, Moontaha S, Steckhan N, Arnrich B.   +4 more
europepmc   +1 more source