Results 61 to 70 of about 5,325 (279)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Threats, Emotions, and Affective Polarization [PDF]
, 2023 Why do some individuals feel hostility and express bias against supporters of other political parties? Drawing on intergroup threat theory, we examine the role of emotions as a mechanism by which perceived threats against the ingroup are a source of ...
Emma A. Renström +6 more
core +1 more source
Social Media + SocietyHow social media fuels affective polarization, characterized by favorability toward in-party members and apathy toward out-party members, has emerged as a crucial topic in political communication.
Heysung Lee, Hernando Rojas
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Political stereotypes and affective polarization [PDF]
This chapter explores the complex relationship between political stereotypes – beliefs about the characteristics of politically defined groups – and affective polarization, emphasizing their potential to reinforce each other.
Harteveld, E.
core +1 more source
Affective polarization in Europe
European Political Science ReviewAbstractAffective polarization, a concept that originated in the USA, has increasingly been studied in Europe’s multi-party systems. This form of polarization refers to the extent to which party supporters dislike one another – or, more technically, to the difference between the positive feelings towards the supporters of one’s own political party and ...
openaire +3 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Territorial disputes and affective polarization [PDF]
Can territorial disputes within countries be a basis for affective polarization? If so, how does it vary across territories? A burgeoning literature on affective polarization has largely focused on partisan divisions; we argue that contentious political ...
Balcells, Laia +2 more
core +1 more source
Does Affective Polarization Undermine Democratic Norms or Accountability? Maybe Not [PDF]
, 2022 Scholars warn that affective polarization undermines democratic norms and accountability: they speculate that if citizens were less affectively polarized, they would be less likely to endorse norm violations, overlook copartisan politicians' shortcomings,
David Broockman +2 more
core +1 more source