Results 51 to 60 of about 1,391,504 (276)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

A feasible algorithm for typing in Elementary Affine Logic

, 2004
We give a new type inference algorithm for typing lambda-terms in Elementary Affine Logic (EAL), which is motivated by applications to complexity and optimal reduction.
A. Asperti, J.-Y. Girard, J.-Y. Girard, J.-Y. Girard, L. Roversi, P. Baillot, P. Coppola, P. Coppola, V. Danos, V. Danos, Y. Lafont   +10 more
core   +4 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

On the Construction of Substitutes

, 2018
Gross substitutability is a central concept in Economics and is connected to important notions in Discrete Convex Analysis, Number Theory and the analysis of Greedy algorithms in Computer Science. Many different characterizations are known for this class,
Balkanski, Eric, Leme, Renato Paes
core   +1 more source

Inteins and affinity resin substitutes for protein purification and scale up [PDF]

Microbial Cell Factories, 2005
Abstract The development of self-cleaving fusion-tag technology has greatly simplified the purification of recombinant proteins at laboratory scale. The self-cleaving capability of these tags has recently been combined with additional purification tags to generate novel and convenient protein purification methods at a variety of scales.
Wood David W, Banki Mahmoud
openaire   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Quantum Jordanian twist

, 2000
The quantum deformation of the Jordanian twist F_qJ for the standard quantum Borel algebra U_q(B) is constructed. It gives the family U_qJ(B) of quantum algebras depending on parameters x and h.
Abdesselam B, Alexander M Mirolubov, Aneva B L, Ballesteros A, Drinfeld V G, Drinfeld V G, Gerstenhaber M, Jimbo M, Jimbo M, Kac V G, Khoroshkin S M, Khoroshkin S M, Kulish P P, Kulish P P, Kulish P P, Kulish P P, Kulish P P, Kupershmidt B A, Lyakhovsky V D, Lyakhovsky V D, Lyakhovsky V D, Mariano A del Olmo, Ogievetsky O V, Ogievetsky O V, Reshetikhin N Yu, Stolin A, Vladimir D Lyakhovsky   +26 more
core   +1 more source

Fast lightweight block cipher design with involution substitution permutation network (SPN) structure

Indonesian Journal of Electrical Engineering and Computer Science, 2020
In the present paper, a new cryptographic lightweight algorithm has been developed for the Internet of Things (IoT) applications. The submitted cipher designed with the involution Substitution Permutation Network SPN structure.
O. Dawood
semanticscholar   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Batch generated strongly nonlinear S-Boxes using enhanced quadratic maps

AIMS Mathematics
One of the most crucial elements in the design of a block cipher is the substitution box or S-box. Its cipher strength directly impacts the cipher algorithm's security, and the block cipher algorithm requires a good S-box.
Mohammad Mazyad Hazzazi, Farooq E Azam, Rashad Ali, Muhammad Kamran Jamil, Sameer Abdullah Nooh, Fahad Alblehai   +5 more
doaj   +1 more source