Results 11 to 20 of about 2,449 (204)

Congenital Afibrinogenemia With Coexisting Factor V Leiden Mutation Complicated by Budd-Chiari Syndrome: A Case Report. [PDF]

Cureus
Congenital afibrinogenemia is a rare autosomal recessive bleeding disorder characterized by the complete absence of fibrinogen, a key protein in the coagulation cascade.
Boutari RA, Hsayan FI, Mallah F, Diab M.
europepmc   +2 more sources

Hereditary afibrinogenemia: A literature review and clinical observations [PDF]

Терапевтический архив, 2016
Afibrinogenemia is a rare congenital coagulopathy that leads to life-threatening bleeding. In afibrinogenemia, plasma fibrinogen levels are less than 0.1 g/L.
E V Yakovleva, V L Surin, D S Selivanova, A M Sergeeva, M V Gonсharova, E Yu Demidova, N P Soboleva, S A Makhinya, A V Dezhenkova, E A Likhacheva, N I Zozulya   +10 more
doaj   +2 more sources

Clinical, biological, and genetic features in an afibrinogenemia patient series in Algeria. [PDF]

Haemophilia, 2022
The incidence of afibrinogenemia had not been previously reported in Algeria. Afibrinogenemia patients are prone to both haemorrhagic and thrombotic complications. Predictive markers of thrombosis in afibrinogenemia patients are not existent.
Hadjali-Saichi S, de Mazancourt P, Tapon-Bretaudière J, Mirault T, Guenounou K, Frigaa I, Fischer AM, Chafa O, Helley D.   +8 more
europepmc   +2 more sources

Afibrinogenemia

Pulse, 2011
Afibrinogenemia is a rare bleeding disorder with an estimated prevalence of 1:10,00,000 [1, 2]. It is an autosomal recessive disease resulting from mutations in any of the 3 genes that encodes the 3 polypeptide chains of fibrinogen and are located on the long arm of chromosome 4 3.
I Islam, Md Moniruzzaman, Pinkoo Attawar, Tahera Nazrin   +3 more
openaire   +3 more sources

Congenital afibrinogenemia in a newborn

Sanamed, 2022
Introduction: Congenital afibrinogenemia is a rare coagulation disorder characterized by a deficiency in the fibrinogen molecule. Fibrinogen is a hexameric glycoprotein consisting of a polypeptide chain encoded by FGB, FGA, and FGG and is required for ...
Özay Mustafa, Kara Mustafa, Keskin Zuhal   +2 more
doaj   +2 more sources

Isolated scalp hematoma: An unusual presentation of congenital afibrinogenemia

Indian Pediatrics Case Reports, 2023
Background: Congenital fibrinogen disorder is a rare autosomal recessive blood coagulation disorder, where majority of patients present with bleeding, whereas a few may paradoxically develop thrombosis.
Arnab Ghorui, Chandra Mohan Kumar, Amrita Banerjee   +2 more
doaj   +2 more sources

Management and Treatment of Bleeding and Thrombotic Complications of Congenital Afibrinogenemia during Chemotherapy and Bone Marrow Transplant for B-ALL [PDF]

Blood
Background Inherited quantitative disorders of fibrinogen are rare and congenital afibrinogenemia (CA) is reported to affect approximately 1:1,000,000 persons worldwide. CA is a clinically heterogenous disease that may involve thrombotic events (TE),
Kimberley Youkhana, Alexander Coltoff, Tharakeswari Selvakumar, Benjamin Djulbegović, Charles S. Greenberg, Shayla Bergmann   +5 more
openalex   +2 more sources

Women With Congenital Hypofibrinogenemia/Afibrinogenemia: From Birth to Death

Clinical and Applied Thrombosis/Hemostasis, 2020
Congenital fibrinogen disorders are a group of most frequent rare coagulation disorder, characterized by deficiency and/or defects in the fibrinogen molecule. Quantitative disorders include hypofibrinogenemia and afibrinogenemia.
Yan Zhang MD, Xiaohang Zuo MD, Yue Teng PhD, MD   +2 more
doaj   +2 more sources

Afibrinogenemia: A rare cause of refractory puberty menorrhagia

Iraqi Journal of Hematology, 2022
Excessive menstruation after attaining menarche during adolescent age group is known as puberty menorrhagia (PM). The most common presentation includes anemia due to excessive blood loss.
Vandana Kamatham, Vijayan Sharmila, Thirunavukkarasu Arun Babu   +2 more
doaj   +2 more sources

The thrombotic paradox in congenital fibrinogen deficiencies: from pathophysiology to practice [PDF]

Research and Practice in Thrombosis and Haemostasis
Congenital fibrinogen deficiencies (CFDs) comprise rare inherited disorders characterized by quantitative (afibrinogenemia, hypofibrinogenemia) or qualitative (dysfibrinogenemia, hypodysfibrinogenemia) abnormalities of fibrinogen.
Samin Mohsenian, Alessandro Casini, Flora Peyvandi   +2 more
doaj   +2 more sources