Combination of Plasma Pharmacochemistry, RNA-Seq, and Molecular Docking Strategies to Reveal the Mechanism of the Alkaloid Fraction of Nelumbinis folium for the Treatment of Hyperlipidemia [PDF]
Nelumbinis folium (N. folium) exhibits hypolipidemic effects and shows great potential for application in lipid-lowering drugs and healthcare products.
Yuan Cai +8 more
doaj +2 more sources
Biomineralized apoferritin nanoparticles delivering dihydroartemisinin and calcium for synergistic breast cancer therapy [PDF]
Breast cancer is one of the most common gynecological malignancies and poses a severe health risk to women. In recent years, ferroptosis therapy has been considered a promising therapeutic strategy for breast cancer by promoting intracellular reactive ...
Shanshan Zhao, Peng Liu, Yan Li
doaj +2 more sources
High efficacy of huCD20-targeted AcTaferon in humanized patient derived xenograft models of aggressive B cell lymphoma [PDF]
Type I interferon (IFN) is a potent antitumoral drug, with an important history in the treatment of hematologic malignancies. However, its pleiotropic nature leads to severe dose-limiting toxicities that blunt its therapeutic potential.
Willem Daneels +13 more
doaj +2 more sources
Prolonged dysregulation of gene expression and biomarkers of coagulation, fibrinolysis, and endothelium in pediatric central nervous system malaria [PDF]
Background Children with central nervous system malaria (CNS-M) have gene expression profiles and plasma biomarkers of malaria pathogenesis that differ from children with uncomplicated malaria (UM, malaria infection with fever and no systemic organ ...
Arlene E. Dent +12 more
doaj +2 more sources
An attenuation field network for dedicated cone beam breast CT with short scan and offset detector geometry [PDF]
The feasibility of full-scan, offset-detector geometry cone-beam CT has been demonstrated for several clinical applications. For full-scan acquisition with offset-detector geometry, data redundancy from complementary views can be exploited during image ...
Zhiyang Fu +2 more
doaj +2 more sources
Effect of anterior femoral cortical notch grade on postoperative function and complications during TKA surgery: A multicenter, retrospective study [PDF]
To explore the effect of AFN on knee function and complications in patients after TKA.
Jin Zhaokai +10 more
doaj +2 more sources
El artículo presenta la conversión de un autómata finito no determinista (AFN) a un autómata finito determinista (AFD), haciendo uso de la construcción por subconjuntos.
Edgar Ruiz L., Eduardo Raffo L.
doaj +3 more sources
Organising Alternative Food Networks (AFNs): Challenges and Facilitating Conditions of different AFN types in three EU countries [PDF]
AbstractThis study aimed to explore the constraining and facilitating factors impacting the emergence and consolidation of different types of alternative food networks (AFNs) in different countries. Drawing on the expertise of organizers of seventeen AFNs, we investigated the conditions and actors that hinder and promote the development of different ...
Ana Poças Ribeiro +4 more
openaire +3 more sources
Deducing the Composition of Venus Cloud Particles with the Autofluorescence Nephelometer (AFN)
The composition, sizes and shapes of particles in the clouds of Venus have previously been studied with a variety of in situ and remote sensor measurements.
Darrel Baumgardner +13 more
doaj +1 more source
Riboceine Rescues Auranofin-Induced Craniofacial Defects in Zebrafish
Craniofacial abnormalities are a common group of congenital developmental disorders that can require intensive oral surgery as part of their treatment. Neural crest cells (NCCs) contribute to the facial structures; however, they are extremely sensitive ...
Megan Leask +6 more
doaj +1 more source

