Liver and spleen of hosts of Rhipicephalus linnaei exposed to synthetic (afoxolaner) and natural acaricides (esters from castor oil). A comparative clinical-morphological study [PDF]
In dogs, Rhipicephalus linnaei transmits pathogens such as Ehrlichia canis, Babesia vogeli, and Hepatozoon canis. The veterinary market has synthetic acaricides to ticks control. Esters derived from castor oil are efficient.
Luís Fernando Sodelli +3 more
doaj +4 more sources
Comparative speed of kill of induced Ixodes scapularis infestations following treatment of dogs with endectocides containing either sarolaner (Simparica Trio™), afoxolaner (NexGard® PLUS), or lotilaner (Credelio Quattro™) [PDF]
Background Ixodes scapularis is a consequential tick species in North America that can transmit multiple pathogens of canine and public health significance. Acaricidal speed is critical for reducing the risk of pathogen transmission.
Kathryn E. Reif +13 more
doaj +3 more sources
Efficacy of oral afoxolaner against Amblyomma maculatum infestations in dogs [PDF]
Amblyomma maculatum, the Gulf Coast tick, is a species of significant veterinary and public health importance, especially because it is a vector of important diseases, such as American canine hepatozoonosis and tidewater spotted fever.
Tielemans Eric +4 more
doaj +5 more sources
Field efficacy assessment of a combination of afoxolaner, moxidectin and pyrantel pamoate to treat dogs naturally infested with Sarcoptes scabiei [PDF]
Canine sarcoptic mange, caused by Sarcoptes scabiei, is a highly contagious and intensely pruritic skin disease in dogs. It is prevalent worldwide and has zoonotic potential.
Antoine Loïc +5 more
doaj +3 more sources
Efficacy of afoxolaner or a combination of afoxolaner and milbemycin oxime against fleas, ticks, lice and/or intestinal nematodes in dogs naturally infested in two urban areas in Brazil [PDF]
Background Infestations with fleas, ticks and intestinal nematodes are commonly identified in domestic dogs and have significant veterinary and public health importances.
Andre A. Cutolo +9 more
doaj +3 more sources
Field efficacy of a combination of afoxolaner, moxidectin and pyrantel pamoate against natural infestation with Otodectes cynotis in dogs [PDF]
Otodectes cynotis is the agent of otodectic mange, a disease affecting wild and domestic felines, canines and mustelids. It is a highly contagious and pruritic condition and a major cause of otitis externa in dogs.
Tielemans Eric +2 more
doaj +2 more sources
A novel method for the determination of isoxazoline derivatives in plasma by ultra-high performance liquid chromatography–tandem mass spectrometry: validation and applicability to screening tests [PDF]
Isoxazoline derivatives such as fluralaner, sarolaner, lotilaner, and afoxolaner are a new class of insecticide and acaricide compounds. These compounds are characterised by rapid action and high efficacy over a period of up to several weeks.
Markowska-Buńka Paulina +3 more
doaj +2 more sources
Saving a species, one mite at a time: efficacy of afoxolaner (NexGard®) against Macronyssidae mites in the critically endangered Aeolian wall lizard (Podarcis raffonei) [PDF]
The Aeolian wall lizard (Podarcis raffonei) is an endangered lacertid species endemic to the Aeolian Archipelago (Sicily, Italy). Its populations are threatened by several factors, including habitat fragmentation and reduction, competition with the ...
Jairo Alfonso Mendoza-Roldan +9 more
doaj +2 more sources
Comparative speed of kill provided by lotilaner (Credelio™), sarolaner (Simparica Trio™), and afoxolaner (NexGard™) to control Amblyomma americanum infestations on dogs [PDF]
Abstract Background Canine acaricides with rapid onset and sustained activity can reduce pathogen transmission risk and enhance pet owner experience.
Kathryn E. Reif +10 more
doaj +2 more sources
Efficacy of a chewable tablet containing sarolaner, moxidectin, and pyrantel (Simparica Trio®) in the treatment of sarcoptic mange caused by Sarcoptes scabiei mite infestations in dogs [PDF]
Background Infestation with Sarcoptes scabiei in dogs is a debilitating disease if left untreated and is transmissible to humans. Two field studies were conducted to confirm the efficacy of orally administered sarolaner in combination with moxidectin and
Csilla Becskei +5 more
doaj +2 more sources

