Results 71 to 80 of about 211,078 (328)

Comparison of diagnostic accuracy of Midkine and AFP for detecting hepatocellular carcinoma: a systematic review and meta-analysis

Bioscience Reports, 2020
Objective: Midkine (MDK) has been proposed as one of the most promising markers for hepatocellular carcinoma (HCC). This meta-analysis was conducted to compare the diagnostic accuracy of MDK and α-fetoprotein (AFP) for HCC.
Qingqing Lu, Jie Li, H. Cao, Chenlu Lv, Xiaolin Wang, S. Cao   +5 more
semanticscholar   +1 more source

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

Serum levels of AFP and CA19-9 after intraoperative radiotherapy combined with drug therapy on liver and pancreatic tumors [PDF]

Journal of Medical Biochemistry
Background: To explore the efficacy of intraoperative radiotherapy combined with drug therapy on serum levels of AFP and CA19-9 for liver and pancreatic tumours to provide more effective treatment strategies for clinical practice.
Jia Xin, Jiang Zongliang
doaj   +1 more source

A cross sectional analysis of the association between FGF19 tumor expression and serum AFP levels in advanced HCC patients [PDF]

, 2017
PURPOSE: HCC is a complicated disease with high mortality rates and limited treatment options. No universal clinical or molecular classification established to inform better treatment options.
Clifford, Corinne
core  

Usefulness of Highly Sensitive AFP-L3 and DCP in Surveillance for Hepatocellular Carcinoma in Patients with a Normal Alpha-Fetoprotein [PDF]

, 2014
Background and aims: Early detection of Hepatocellular Carcinoma (HCC) is crucial for effective management. Incidence of HCC has increased in the United States largely attributed to hepatitis B and C virus.
Coben, Robert, DiMarino, Anthony J., Hann, Hie-Won, Li, Dave, Satomura, Shinji, Yamada, Hiroyuki   +5 more
core   +2 more sources

�� ���������������������� �������������� ������ AFP �������� ������ ������ ��������������, ������ ������ ���������������� ������������������ ������ ����������������������

, 2009
AFP , .
openaire   +2 more sources

Diagnostic value of fibrinogen to prealbumin ratio and gamma-glutamyl transpeptidase to platelet ratio in the progression of AFP-negative hepatocellular carcinoma

Cancer Cell International, 2020
This study aimed to comprehensively assess the diagnostic value of fibrinogen to prealbumin ratio (FPR) and gamma-glutamyl transpeptidase to platelet ratio (GPR) as single markers or in combination in patients with alpha-fetoprotein-negative (AFP ...
Li Huang, Z. Mo, Zuojian Hu, Linyan Zhang, Shanzi Qin, X. Qin, Shan Li   +6 more
semanticscholar   +1 more source

Disrupting the Formation of YAP Condensates Promotes the Activation of AMPKα to Inhibit the Progression of Primary Liver Cancer

Advanced Science, EarlyView.
This study systematically investigates the function and molecular mechanisms of YAP phase separation in multiple primary liver cancers. These findings provide novel insights into phase separation‐mediated primary liver cancer development and validate targeted disruption of this process as an effective therapeutic strategy for primary liver cancer ...
Shuang‐Zhou Peng, Jia‐Jia Liang, Yun‐Feng Zhan, Wei‐Xun Wu, Wan‐Li Xu, Xiao‐Kun Zhang, Li‐Jun Cai, Fu‐Quan Jiang   +7 more
wiley   +1 more source

First and Second Trimester Biochemical Markers in Familial Mediterranean Fever

Medicine Science, 2016
Familial Mediterranean Fever (FMF) is the most common hereditary monogenic auto-inflammatory disease. In this study we aimed to document whether FMF affects the biochemical components of first and second trimester combined aneuploidy screening tests ...
Ayse Kirbas, Korkut Daglar, Hakan Timur, Gulenay Gencosmanoglu, Ozgur Kara, Zehra Yilmaz, Hasan Ali Inal, Nuri Danisman   +7 more
doaj   +1 more source

Alpha-Fetoprotein in Predicting Survival of Patients with Ruptured Hepatocellular Carcinoma after Resection

Journal of Investigative Surgery, 2022
Background/Aim: Alpha-fetoprotein (AFP) had been used as a prognostic factor in hepatocellular carcinoma but it was unknown what level of AFP could predict the survival of patients with ruptured hepatocellular carcinoma (rHCC) after resection.
Wong Hoi She, Miu Yee Chan, Ka Wing Ma, Simon H. Y. Tsang, Wing Chiu Dai, Albert C. Y. Chan, Chung Mau Lo, Tan To Cheung   +7 more
doaj   +1 more source