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Genotype I African swine fever viruses emerged in domestic pigs in China and caused chronic infection

open access: yesEmerging Microbes and Infections, 2021
The Georgia-07-like genotype II African swine fever virus (ASFV) with high virulence has been prevalent in China since 2018. Here, we report that genotype I ASFVs have now also emerged in China. Two non-haemadsorbing genotype I ASFVs, HeN/ZZ-P1/21 and SD/
Encheng Sun   +20 more
doaj   +2 more sources

African Swine Fever Diagnosis in Africa: Challenges and Opportunities [PDF]

open access: goldPathogens
The global spread of African swine fever (ASF) in recent decades has led to the need for technological advances in sampling and diagnostic techniques.
M. Penrith   +9 more
semanticscholar   +2 more sources

Attenuated African swine fever viruses and the live vaccine candidates: a comprehensive review

open access: yesMicrobiology Spectrum
The African swine fever virus (ASFV) is spreading worldwide and causing huge economic losses to the global pig industry. The ASFV genome is 170–193 kb in length, contains approximately 150 open reading frames, and encodes more than 200 proteins, most of ...
Jiaqi Fan   +4 more
doaj   +2 more sources

A Pool of Ferritin Nanoparticles Delivering Six Proteins of African Swine Fever Virus Induces Robust Humoral and Cellular Immune Responses in Pigs [PDF]

open access: yesVaccines
Background/Objectives: Inadequate characterization of protective antigens poses a significant challenge to the development of vaccines for African swine fever (ASF), particularly for antigen-dependent formulations such as subunit, mRNA, and recombinant ...
Zhanhao Lu   +11 more
doaj   +2 more sources

Detection of a Novel African Swine Fever Virus with Three Large-Fragment Deletions in Genome, China

open access: yesMicrobiology Spectrum, 2022
We reported a novel African swine fever virus (ASFV) strain that had a three-large-fragment deletion and unique variations in genome. This isolate displayed a nonhemadsorbing phenotype and had homogeneous proliferation compared with the wild-type ASFV ...
Yankuo Sun   +9 more
doaj   +1 more source

Whole-genome sequencing of African swine fever virus from wild boars in the Kaliningrad region reveals unique and distinguishing genomic mutations

open access: yesFrontiers in Veterinary Science, 2023
IntroductionSince the first report of outbreaks of African swine fever (ASF) in Georgia in 2007, the disease has expanded into Europe, Russia, and Asia, spreading rapidly via contact with infected animals including domestic pigs and wild boars.
Ali Mazloum   +9 more
doaj   +1 more source

Comparative Analysis of Full Genome Sequences of African Swine Fever Virus Isolates Taken from Wild Boars in Russia in 2019

open access: yesPathogens, 2021
In this study, we report on the full genome phylogenetic analysis of four ASFV isolates obtained from wild boars in Russia. These samples originated from two eastern and two western regions of Russia in 2019.
Ali Mazloum   +6 more
doaj   +1 more source

Genetic Characterization of the Central Variable Region in African Swine Fever Virus Isolates in the Russian Federation from 2013 to 2017

open access: yesPathogens, 2022
African swine fever virus (ASFV), classified as genotype II, was introduced into Georgia in 2007, and from there, it spread quickly and extensively across the Caucasus to Russia, Europe and Asia. The molecular epidemiology and evolution of these isolates
Ali Mazloum   +6 more
doaj   +1 more source

Interaction network of African swine fever virus structural protein p30 with host proteins

open access: yesFrontiers in Microbiology, 2022
African swine fever virus (ASFV) is a complex nucleocytoplasmic large DNA virus (NCLDV) that causes a lethal hemorrhagic disease that is currently threatening the global pig industry. ASFV structural protein p30 is a membrane phosphoprotein that suggests
Xiongnan Chen   +27 more
doaj   +1 more source

Evaluation of African Swine Fever Virus E111R Gene on Viral Replication and Porcine Virulence

open access: yesViruses, 2023
African swine fever (ASF) is an acute infectious disease of domestic pigs and wild boars caused by the African swine fever virus (ASFV), with up to a 100% case fatality rate. The development of a vaccine for ASFV is hampered by the fact that the function
Xintao Zhou   +11 more
doaj   +1 more source

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