Results 21 to 30 of about 72,115 (295)

African swine fever virus I73R is a critical virulence-related gene: A potential target for attenuation

Proceedings of the National Academy of Sciences of the United States of America, 2023
Significance African swine fever virus (ASFV) is the etiological agent for the highly contagious and fatal African swine fever (ASF) in pigs. The virulence-related genes and the mechanism of immune escape of ASFV are unclear, raising safety concerns of ...
Yingnan Liu, Zhou Shen, Zhenhua Xie, Yingying Song, Yao Li, R. Liang, L. Gong, Dong-dong Di, Jianqi Liu, Jingyi Liu, Zongyan Chen, Wanqi Yu, Lu Lv, Qi Zhong, Xinxin Liao, Chuanwen Tian, Rongrong Wang, Qingqing Song, Heng Wang, Guiqing Peng, Hongjun Chen   +20 more
semanticscholar   +1 more source

African Swine Fever Virus Infection and Cytokine Response In Vivo: An Update

Viruses, 2023
African swine fever (ASF) is a hemorrhagic viral disease of domestic pigs and wild suids (all Sus scrofa) caused by the ASF virus (ASFV). The disease is spreading worldwide without control, threatening pig production due to the absence of licensed ...
G. Franzoni, M. Pedrera, P. Sánchez-Cordón   +2 more
semanticscholar   +1 more source

A multi gene-approach genotyping method identifies 24 genetic clusters within the genotype II-European African swine fever viruses circulating from 2007 to 2022

Frontiers in Veterinary Science, 2023
Introduction African swine fever (ASF) is a contagious viral disease of pigs and wild boar that poses a major threat to the global swine industry. The genotype II African swine fever virus (ASFV) entered the European Union (EU) in 2014 and since then ...
C. Gallardo, Nadia Casado, A. Soler, Igor Djadjovski, Laura Krivko, E. Madueño, R. Nieto, C. Pérez, A. Simón, E. Ivanova, D. Donescu, Vesna Milicevik, E. Chondrokouki, I. Nurmoja, M. Frant, F. Feliziani, P. Václavek, S. Pilevičienė, Arias Marisa   +18 more
semanticscholar   +1 more source

Rhein suppresses African swine fever virus replication in vitro via activating the caspase-dependent mitochondrial apoptosis pathway

Virus Research, 2023
African swine fever (ASF) is a virulent infectious diseases of pigs caused by the African swine fever virus (ASFV) that can spread widely and cause high fatality rates.
Zebu Song, Yang Chen, Hao Chang, Yanchen Guo, Qi Gao, Zhi Wei, Lang Gong, Guihong Zhang, ZeZhong Zheng   +8 more
doaj   +1 more source

African Swine Fever Virus pE199L Induces Mitochondrial-Dependent Apoptosis

Viruses, 2021
African swine fever (ASF) is a severe hemorrhagic disease in swine characterized by massive lymphocyte depletion and cell death, with apoptosis and necrosis in infected lymphoid tissues.
Tingting Li, Gaihong Zhao, Taoqing Zhang, Zhaoxia Zhang, Xin Chen, Jie Song, Xiao Wang, Jiangnan Li, Li Huang, Lili Wen, Changyao Li, Dongming Zhao, Xijun He, Zhigao Bu, Jun Zheng, Changjiang Weng   +15 more
doaj   +1 more source

Epidemiological analysis of African swine fever in the European Union during 2022

EFSA journal. European Food Safety Authority, 2023
This report presents the epidemiological analysis of African swine fever (ASF) during 2022 based on the surveillance and pig population data submitted by the European Union (EU) affected countries and one neighbouring country.
K. Ståhl, A. Boklund, T. Podgórski, T. Vergne, J. Abrahantes, A. Papanikolaou, G. Zancanaro, L. Mur   +7 more
semanticscholar   +1 more source

A candidate nanoparticle vaccine comprised of multiple epitopes of the African swine fever virus elicits a robust immune response

Journal of Nanobiotechnology, 2023
The African swine fever (ASF) pandemics pose a significant threat to the global swine industry, and the development of safe and effective vaccines is a daunting but necessary challenge.
Jinxing Song, Mengxiang Wang, Lei Zhou, Panpan Tian, Zhuoya Sun, Junrun Sun, Xuannian Wang, G. Zhuang, Dawei Jiang, Yanan Wu, Gaiping Zhang   +10 more
semanticscholar   +1 more source

A new vaccination regimen using adenovirus-vectored vaccine confers effective protection against African swine fever virus in swine

Emerging Microbes and Infections, 2023
African swine fever (ASF) is an acute and highly contagious lethal infectious disease in swine that severely threatens the global pig industry. At present, a safe and efficacious vaccine is urgently required to prevent and control the disease.
Wenming Liu, Hengchun Li, Bo Liu, T. Lv, Chenchen Yang, Si Chen, Liqiang Feng, L. Lai, Ziyuan Duan, Xinwen Chen, Pingchao Li, Suhua Guan, Ling Chen   +12 more
semanticscholar   +1 more source

A Triplex PCR Method for Distinguishing the Wild-Type African Swine Fever Virus From the Deletion Strains by Detecting the Gene Insertion

Frontiers in Veterinary Science, 2022
To date, there is no effective vaccine or antiviral therapy available to prevent or treat African swine fever virus (ASFV) infections. ASFV gene deletion strains have been proposed as promising anti-ASFV vaccine candidates.
Zhao Huang, Zhao Huang, Zhiying Xu, Zhiying Xu, Haoxuan Cao, Haoxuan Cao, Fanliang Zeng, Fanliang Zeng, Heng Wang, Heng Wang, Heng Wang, Lang Gong, Lang Gong, Shengxun Zhang, Sen Cao, Guihong Zhang, Guihong Zhang, Guihong Zhang, Guihong Zhang, Zezhong Zheng, Zezhong Zheng   +20 more
doaj   +1 more source

African swine fever control and prevention: an update on vaccine development

Emerging Microbes and Infections, 2022
African swine fever (ASF) is a lethal and highly contagious viral disease of domestic and wild pigs, listed as a notifiable disease reported to the World Organization for Animal Health (OIE).
A. Urbano, F. Ferreira
semanticscholar   +1 more source