Results 21 to 30 of about 44,107 (258)

African Swine Fever Virus Infection and Cytokine Response In Vivo: An Update

Viruses, 2023
African swine fever (ASF) is a hemorrhagic viral disease of domestic pigs and wild suids (all Sus scrofa) caused by the ASF virus (ASFV). The disease is spreading worldwide without control, threatening pig production due to the absence of licensed ...
G. Franzoni, M. Pedrera, P. Sánchez-Cordón   +2 more
semanticscholar   +1 more source

African swine fever virus I73R is a critical virulence-related gene: A potential target for attenuation

Proceedings of the National Academy of Sciences of the United States of America, 2023
Significance African swine fever virus (ASFV) is the etiological agent for the highly contagious and fatal African swine fever (ASF) in pigs. The virulence-related genes and the mechanism of immune escape of ASFV are unclear, raising safety concerns of ...
Yingnan Liu, Zhou Shen, Zhenhua Xie, Yingying Song, Yao Li, R. Liang, L. Gong, Dong-dong Di, Jianqi Liu, Jingyi Liu, Zongyan Chen, Wanqi Yu, Lu Lv, Qi Zhong, Xinxin Liao, Chuanwen Tian, Rongrong Wang, Qingqing Song, Heng Wang, Guiqing Peng, Hongjun Chen   +20 more
semanticscholar   +1 more source

A new vaccination regimen using adenovirus-vectored vaccine confers effective protection against African swine fever virus in swine

Emerging Microbes and Infections, 2023
African swine fever (ASF) is an acute and highly contagious lethal infectious disease in swine that severely threatens the global pig industry. At present, a safe and efficacious vaccine is urgently required to prevent and control the disease.
Wenming Liu, Hengchun Li, Bo Liu, T. Lv, Chenchen Yang, Si Chen, Liqiang Feng, L. Lai, Ziyuan Duan, Xinwen Chen, Pingchao Li, Suhua Guan, Ling Chen   +12 more
semanticscholar   +1 more source

African swine fever

EFSA Journal, 2015
Since entering the eastern EU at the start of 2014, African swine fever (ASF) has spread locally in the wild boar population, independently of outbreaks in domestic pigs. No correlation between the density of the wild boar population and the case notification in an area has been observed.
Berg, Charlotte, Bøtner, Anette, Browman, Howard, De Koeijer, Aline, Domingo, Mariano, Ducrot, Christian, Edwards, Sandra, Fourichon, Christine, Koenen, Frank, More, Simon, Raj, Mohan, Sihvonen, Liisa, Spoolder, Hans, Stegeman, Jan Arend, Thulke, Hans-Hermann, Vågsholm, Ivar, Velarde, Antonio, Willeberg, Preben   +17 more
openaire   +4 more sources

Structure and function of African swine fever virus proteins: Current understanding

Frontiers in Microbiology, 2023
African swine fever virus (ASFV) is a highly infectious and lethal double-stranded DNA virus that is responsible for African swine fever (ASF). ASFV was first reported in Kenya in 1921.
Si-Yong Yang, Chun Miao, Wei Liu, Guanglei Zhang, Junjun Shao, Huiyun Chang   +5 more
semanticscholar   +1 more source

Deletion of DP148R, DP71L, and DP96R Attenuates African Swine Fever Virus, and the Mutant Strain Confers Complete Protection against Homologous Challenges in Pigs

Journal of Virology, 2023
Ongoing outbreaks of African swine fever (ASF) have considerably damaged the pig industry in affected countries. Thus, a safe and effective vaccine is important to control African swine fever spread.
X. Qi, Tao Feng, Zhao Ma, Linlin Zheng, Huanan Liu, Zhengwang Shi, Chao-chao Shen, Pan Li, Pan-Xue Wu, Yi Ru, Dan Li, Zixiang Zhu, H. Tian, Sen Wu, Haixue Zheng   +14 more
semanticscholar   +1 more source

African Swine Fever Virus pE199L Induces Mitochondrial-Dependent Apoptosis

Viruses, 2021
African swine fever (ASF) is a severe hemorrhagic disease in swine characterized by massive lymphocyte depletion and cell death, with apoptosis and necrosis in infected lymphoid tissues.
Tingting Li, Gaihong Zhao, Taoqing Zhang, Zhaoxia Zhang, Xin Chen, Jie Song, Xiao Wang, Jiangnan Li, Li Huang, Lili Wen, Changyao Li, Dongming Zhao, Xijun He, Zhigao Bu, Jun Zheng, Changjiang Weng   +15 more
doaj   +1 more source

African Swine Fever Virus (ASFV): Immunity and Vaccine Development

Vaccines, 2023
African swine fever virus (ASFV) is the causative agent of the highly contagious disease African swine fever (ASF), which can result in mortality rates of up to 100% in pigs infected by virulent strains [...].
Kiramage Chathuranga, Jong-Soo Lee
semanticscholar   +1 more source

Establishment of a Dual Real-Time PCR Assay for the Identification of African Swine Fever Virus Genotypes I and II in China

Frontiers in Veterinary Science, 2022
Since the first outbreak of ASFV genotype II in China in 2018, ASF has posed a significant threat to the swine industry. After the emergence of genotype I in China in 2020, the epidemic prevention and control have become more difficult.
Qi Gao, Qi Gao, Qi Gao, Yongzhi Feng, Yongzhi Feng, Yunlong Yang, Yunlong Yang, Yizhuo Luo, Yizhuo Luo, Ting Gong, Ting Gong, Heng Wang, Heng Wang, Heng Wang, Lang Gong, Lang Gong, Lang Gong, Guihong Zhang, Guihong Zhang, Guihong Zhang, Zezhong Zheng, Zezhong Zheng, Zezhong Zheng   +22 more
doaj   +1 more source

Characterization of a Novel African Swine Fever Virus p72 Genotype II from Nigeria

Viruses, 2023
African swine fever (ASF) is a high-consequence transboundary hemorrhagic fever of swine. It continues to spread across the globe causing socio-economic issues and threatening food security and biodiversity. In 2020, Nigeria reported a major ASF outbreak,
A. Ambagala, K. Goonewardene, Lindsey L. Lamboo, M. Goolia, Cassidy N G Erdelyan, M. Fisher, K. Handel, O. Lung, S. Blome, Jacqueline King, J. Forth, S. Calvelage, Edward Spinard, D. Gladue, C. Masembe, A. Adedeji, T. Olubade, N. Maurice, H. Ularamu, P. Luka   +19 more
semanticscholar   +1 more source