Results 21 to 30 of about 13,633 (161)

CD1d facilitates African swine fever virus entry into the host cells via clathrin-mediated endocytosis

open access: yesEmerging Microbes and Infections, 2023
African swine fever (ASF) is a highly contagious and acute hemorrhagic viral disease with high morbidity and mortality in domestic pigs and wild boars. The disease has become a global threat to the pig production industry and has caused enormous economic
Xin Chen   +11 more
doaj   +1 more source

African swine fever virus morphogenesis

open access: yesVirus Research, 2013
This review summarizes recent structural and molecular biology studies related to the morphogenesis of African swine fever virus (ASFV). ASFV possesses icosahedral morphology and is constituted by four concentric layers: the central nucleoid, the core shell, the inner envelope and the icosahedral capsid.
Salas Falgueras, María Luisa   +1 more
openaire   +3 more sources

Genotype I African swine fever viruses emerged in domestic pigs in China and caused chronic infection

open access: yesEmerging Microbes and Infections, 2021
The Georgia-07-like genotype II African swine fever virus (ASFV) with high virulence has been prevalent in China since 2018. Here, we report that genotype I ASFVs have now also emerged in China. Two non-haemadsorbing genotype I ASFVs, HeN/ZZ-P1/21 and SD/
Encheng Sun   +20 more
doaj   +1 more source

An improved luciferase immunosorbent assay for ultrasensitive detection of antibodies against African swine fever virus

open access: yesFrontiers in Microbiology, 2022
African swine fever (ASF), caused by African swine fever virus (ASFV), is a fatal infectious disease of pigs and causes great socioeconomic losses globally. The reliable diagnostic method is critical for prevention and control of the disease.
Qiongjie Wang   +10 more
doaj   +1 more source

Transcriptome Profiling Reveals Features of Immune Response and Metabolism of Acutely Infected, Dead and Asymptomatic Infection of African Swine Fever Virus in Pigs

open access: yesFrontiers in Immunology, 2021
African swine fever virus (ASFV) infection can result in lethal disease in pigs. ASFV encodes 150-167 proteins, of which only approximately 50 encoded viral structure proteins are functionally known. ASFV also encodes some nonstructural proteins that are
Hualin Sun   +15 more
doaj   +1 more source

African Swine Fever Epidemiology and Control [PDF]

open access: yesAnnual Review of Animal Biosciences, 2020
African swine fever is a devastating disease that can result in death in almost all infected pigs. The continuing spread of African swine fever from Africa to Europe and recently to the high–pig production countries of China and others in Southeast Asia threatens global pork production and food security.
Dixon, Linda K.   +4 more
openaire   +5 more sources

Novel P22-monoclonal antibody based blocking ELISA for the detection of African swine fever virus antibodies in serum

open access: yesBiosafety and Health, 2022
African swine fever (ASF) is a highly infectious, transboundary viral disease of domestic and wild pigs, and is currently the most serious threat to world swine production, resulting in significant economic loss. In the absence of vaccines and treatments,
Ghebremedhin Tsegay   +12 more
doaj   +1 more source

Clinical Validation of Two Recombinase-Based Isothermal Amplification Assays (RPA/RAA) for the Rapid Detection of African Swine Fever Virus

open access: yesFrontiers in Microbiology, 2020
African swine fever (ASF), caused by African swine fever virus (ASFV), is a devastating infectious disease of domestic pigs and wild boars, and has tremendous negative socioeconomic impact on the swine industry and food security worldwide.
Xiaoxu Fan   +17 more
doaj   +1 more source

Evaluation of Haematological and Immunological Parameters of the ASFV Lv17/WB/Rie1 Strain and Its Derived Mutant Lv17/WB/Rie1/d110-11L against ASFV Challenge Infection in Domestic Pigs

open access: yesVaccines, 2023
African swine fever virus (ASFV) is the etiological agent of a haemorrhagic disease that threatens the global pig industry. There is an urgency to develop a safe and efficient vaccine, but the knowledge of the immune–pathogenetic mechanisms behind ASFV ...
Giulia Franzoni   +12 more
doaj   +1 more source

Unpicking the Secrets of African Swine Fever Viral Replication Sites

open access: yesViruses, 2021
African swine fever virus (ASFV) is a highly contagious pathogen which causes a lethal haemorrhagic fever in domestic pigs and wild boar. The large, double-stranded DNA virus replicates in perinuclear cytoplasmic replication sites known as viral ...
Sophie-Marie Aicher   +3 more
doaj   +1 more source

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