Results 41 to 50 of about 45,459 (317)

Transmission routes of African swine fever virus to domestic pigs: current knowledge and future research directions [PDF]

, 2016
African swine fever (ASF) is a major threat to the pig industry in Europe. Since 2007, ASF outbreaks have been ongoing in the Caucasus, Eastern Europe and the Baltic countries, causing severe economic losses for many pig farmers and pork producers.
BALDACCHINO, BLOME, BOINAS, COSTARD, DAVIES, DE CARVALHO FERREIRA, DE CARVALHO FERREIRA, DE CARVALHO FERREIRA, DE CARVALHO FERREIRA, DIAZ, EC, EC, EC, EC, EC, EFSA, EU, FAO, FAO, GABRIEL, GALLARDO, GALLARDO, GALLARDO, GOGIN, GREIG, GREIG, GUINAT, GUINAT, GULENKIN, HAAS, HEUSCHELE, HOWEY, IGLESIAS, KAGIRA, LANGE, MANZANO-ROMÁN, MCKERCHER, MCVICAR, MEBUS, MEBUS, MELLOR, MONTGOMERY, OGANESYAN, OIE, PARKER, PHENGSAVANH, PIETSCHMANN, PLOWRIGHT, PLOWRIGHT, PLOWRIGHT, ROWLANDS, SANCHEZ BOTIJA, SANCHEZ BOTIJA, SODEIKAT, THOMSON, THURFJELL, TURNER, VERGNE, VERGNE, VLASOVA, WILKINSON   +60 more
core   +2 more sources

Riding apoptotic bodies for cell–cell transmission by African swine fever virus

Proceedings of the National Academy of Sciences of the United States of America, 2023
Significance ASFV is a leading threat to the world pork production and has evolved a mechanism to avoid antibody neutralization, contributing to viral persistence within infected pigs. We report here that ASFV highjacks the cellular efferocytosis pathway
Peng Gao, Lei Zhou, Jiajun Wu, Wenlian Weng, Hua Wang, Miaomiao Ye, Yajin Qu, Yuxin Hao, Yongning Zhang, X. Ge, Xin Guo, Jun Han, Hanchun Yang   +12 more
semanticscholar   +1 more source

African Swine Fever Virus Guanylyltransferase

Virology, 1993
The gene coding for the guanylyltransferase of African swine fever virus has been identified and sequenced. The gene, designated NP868R, is located within fragments EcoRI N' and D of the virus genome (BA71V strain) and encodes a protein with a predicted molecular mass of 99.9 kDa that shares significant similarity with the large subunit of both ...
Pena, L., Yáñez, R. J., Revilla Novella, Yolanda, Viñuela, Eladio, Salas Falgueras, María Luisa   +4 more
openaire   +4 more sources

Autophagy impairment by African swine fever virus

Journal of General Virology, 2021
African swine fever is a devastating disease of domestic swine and wild boar caused by a large double-stranded DNA virus that encodes for more than 150 open reading frames. There is no licensed vaccine for the disease and the most promising current candidates are modified live viruses that have been attenuated by deletion of virulence factors.
Joshua Y. K. Hui, Christopher L. Netherton, Gareth Shimmon, Thomas Wileman, Thomas Wileman   +4 more
openaire   +5 more sources

Territorial pattern between outbreaks of ASF among wild and domestic pigs in Ukraine

Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки, 2021
The article presents the results of the analysis of the epizootic situation in Ukraine regarding African swine fever among domestic and wild pigs from 2012 to 2020 and identifies the main sources of virus spread as well as weak links in the biological ...
Ye. O. Dudnyk
doaj   +1 more source

Experimental pig-to-pig transmission dynamics for African swine fever virus, Georgia 2007/1 strain [PDF]

, 2015
African swine fever virus (ASFV) continues to cause outbreaks in domestic pigs and wild boar in Eastern European countries. To gain insights into its transmission dynamics, we estimated the pig-to-pig basic reproduction number (R 0) for the Georgia 2007 ...
Burnham, C. GUINAT, D. U. PFEIFFER, Diekmann, J. L. GONZALES, Keeling, L. DIXON, McVicar, S. GUBBINS, T. VERGNE, Vynnycky   +10 more
core   +2 more sources

African Swine Fever Virus MGF-505-7R Negatively Regulates cGAS–STING-Mediated Signaling Pathway

Journal of Immunology, 2021
Key Points ASFV MGF-505-7R inhibits cGAS–STING signaling. MGF-505-7R–deficient ASFV was fully attenuated in pigs at a dose of 10 HAD50. Visual Abstract African swine fever virus (ASFV) is a devastating infectious disease in pigs, severely threatening the
Dan Li, Wenping Yang, Lulu Li, Pan Li, Zhao Ma, Jing Zhang, X. Qi, Jingjing Ren, Yi Ru, Q. Niu, Zhijie Liu, Xiang-tao Liu, Haixue Zheng   +12 more
semanticscholar   +1 more source

African swine fever virus morphogenesis

Virus Research, 2013
This review summarizes recent structural and molecular biology studies related to the morphogenesis of African swine fever virus (ASFV). ASFV possesses icosahedral morphology and is constituted by four concentric layers: the central nucleoid, the core shell, the inner envelope and the icosahedral capsid.
Salas Falgueras, María Luisa, Andrés, Germán   +1 more
openaire   +3 more sources

Dynamics of African swine fever virus shedding and excretion in domestic pigs infected by intramuscular inoculation and contact transmission [PDF]

, 2014
African swine fever virus (ASFV) is a highly virulent swine pathogen that has spread across Eastern Europe since 2007 and for which there is no effective vaccine or treatment available.
Dixon, L, Goatley, L, Guinat, C, Netherton, C L, Pfeiffer, D U, Pirbright, Reis, A L   +6 more
core   +5 more sources

The African swine fever virus I10L protein inhibits the NF-κB signaling pathway by targeting IKKβ

Journal of Virology, 2023
Proinflammatory factors play important roles in the pathogenesis of African swine fever virus (ASFV), which is the causative agent of African swine fever (ASF), a highly contagious and severe hemorrhagic disease.
Xing-Yuan Chen, Lianfeng Li, Zhongning Yang, Meilin Li, Shuai Fan, Lanbo Shi, Zixin Ren, Xuezhi Cao, Yuhang Zhang, Shichong Han, Bo Wan, H. Qiu, Gai-Ping Zhang, Wen-Rui He   +13 more
semanticscholar   +1 more source