Results 71 to 80 of about 20,286 (224)

Pyroptosis in Peripheral Neuropathy: From Molecular Mechanisms to Therapeutic Targeting

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Pyroptosis is a key inflammatory cell death pathway in peripheral neuropathy, with opposing roles: it perpetuates neuropathic pain but can be induced to kill neuroblastoma cells. This review consolidates mechanistic understanding and therapeutic strategies, arguing for a shift from disease‐centric to target‐centric treatment approaches to improve ...
Jinhuan Wei, Mingyue Liuyuan, Zhixin Ye, Xueying Wang, Xueli Zhou, Yifan Shan, Cheng He, Chunting Zhu, Chicheng Zhou, Jingyin Bao, Yonghui Zhang, Gang Chen   +11 more
wiley   +1 more source

Viral modulation of interferon (IFN) responses to african swine fever virus (ASFV) [PDF]

, 2011
Tese de mestrado. Biologia (Biologia Humana e Ambiente). Universidade de Lisboa, Faculdade de Ciências, 2011A imunidade inata constitui a primeira resposta dada por um hospedeiro quando atacado por agentes patogénicos. A resposta imune baseia-se em genes
Costa, Emanuel Nery de Oliveira Quartin, 1986-
core  

Zoonosis emergence linked to agricultural intensification and environmental change [PDF]

, 2013
A systematic review was conducted by a multidisciplinary team to analyze qualitatively best available scientific evidence on the effect of agricultural intensification and environmental changes on the risk of zoonoses for which there are epidemiological ...
Artois, B. A. Jones, Belotto, Boureau, Brown, Childs, Chomel, Chua, Cleaveland, Cutler, D. Grace, D. McKeever, D. U. Pfeiffer, Daszak, Drew, Drexler, Ducheyne, Dugan, Epstein, Epstein, F. Mutua, Fevre, Field, Gilchrist, Goldberg, Graham, Harper, Hayman, Hsu, Irvine, J. McDermott, J. Rushton, J. Young, Jones, Keesing, Landolt, Lehle, Leibler, Leroy, M. Y. Said, Mas-Coma, Mathews, Maudlin, McMichael, Morse, Pepin, Pfeffer, R. Kock, Reynes, Rwego, S. Alonso, Sendow, Sims, Springbett, Tricco, van den Hurk, Vora, Wacharapluesadee, Woolhouse, Yob   +59 more
core   +1 more source

Pathogenicity and virulence of African swine fever virus

Virulence
African swine fever (ASF) is a devastating disease with a high impact on the pork industry worldwide. ASF virus (ASFV) is a very complex pathogen, the sole member of the family Asfaviridae, which induces a state of immune suppression in the host through ...
Ines Ruedas-Torres, Bui Thi to Nga, Francisco J. Salguero   +2 more
doaj   +1 more source

Influenza Surveillance in the Central African Republic From 2015 to 2018 to Inform Vaccination and Treatment Strategies

Influenza and Other Respiratory Viruses, Volume 20, Issue 1, January 2026.
ABSTRACT Background Surveillance of influenza infections and virus characterisation are essential to guide prevention strategies. In the Central African Republic (CAR), data on influenza viruses are patchy and poorly documented. Objective To study the clinical, seasonal, genetic and phenotypic characteristics of influenza viruses circulating in the CAR
Giscard Francis Komoyo, Chantal J. Snoeck, Rod S. Daniels, Marie R. Belizaire, Judith M. Hübschen, Claude P. Muller, Pierre Somse, Yap Boum II, Emmanuel Nakoune, John W. McCauley   +9 more
wiley   +1 more source

Phylogeography of Japanese encephalitis virus:genotype is associated with climate [PDF]

, 2013
The circulation of vector-borne zoonotic viruses is largely determined by the overlap in the geographical distributions of virus-competent vectors and reservoir hosts.
A Igarashi, A Oya, A Rambaut, A Rambaut, AB Sabin, AJ Auguste, AJ Drummond, AJ Drummond, AJ Schuh, AJ Schuh, AJ Schuh, Alan D. T. Barrett, Amy C. Morrison, Amy J. Schuh, Andrew J. Leigh Brown, B Shapiro, BJ Smith, D Martin, D Posada, DP Martin, DP Martin, EK Cruickshank, EL Buescher, EL Buescher, EL Buescher, EL Buescher, EL Buescher, FA Rey, FJ May, G Baele, GL Campbell, GM Jenkins, H Tsuchie, H Weissenbock, HS Hurlbut, HY Wang, J Fox, J Parker, JE Bryant, JH Nam, JL Wang, JM Smith, JN Hanna, L Lewis, L Rosen, L Rosen, L Rosen, M Gouy, M Padidam, MA Mohammed, MA Suchard, Melissa J. Ward, MH Li, N Nitatpattana, P Lemey, PD Uchil, PT Nga, PV Fulmali, R Takhampunya, RS Lanciotti, S Guindon, S Kumar, SE Sulkin, SE Sulkin, SL Kosakovsky Pond, SL Kosakovsky Pond, SL Pond, SL Pond, SP Ma, T Bakonyi, T Mitamura, T Solomon, TJ Chambers, WF Scherer, WF Scherer, WF Scherer, WM Hammon, WR Chen, WR Chen, WS Paul, XL Pan, Y Kobayashi, YX Li, YY Chen   +83 more
core   +3 more sources

Epidemiology and Risk Modelling of Influenza A Virus Within and Between Pig Herds in Northern Lao PDR

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Animal‐origin influenza A virus (IAV) is a perennial candidate for causing the next pandemic. With high risk for interspecies IAV transmission but limited resources for surveillance, particularly in rural areas of low‐ and middle‐income countries (LMICs) such as Laos, there is a need to develop targeted, risk‐based strategies for early detection of ...
Arata Hidano, William T. M. Leung, Souk Phomhacksa, Anna Durrance-Bagale, Jose A. Garcia-Rivera, Anca Selariu, Robert D. Hontz, Andrew G. Letizia, Watthana Theppangna, James W. Rudge, Zhi-Jie Zhang   +10 more
wiley   +1 more source

African Swine Fever Virus Isolate, Georgia, 2007

Emerging Infectious Diseases, 2008
African swine fever (ASF) is widespread in Africa but is rarely introduced to other continents. In June 2007, ASF was confirmed in the Caucasus region of Georgia, and it has since spread to neighboring countries. DNA fragments amplified from the genome of the isolates from domestic pigs in Georgia in 2007 were sequenced and compared with other ASF ...
Rowlands, Rebecca J., Michaud, Vincent, Heath, Livio, Hutchings, Geoff, Oura, Chris, Vosloo, Wilna, Dwarka, Rahana, Onashvili, Tinatin, Albina, Emmanuel, Dixon, Linda K.   +9 more
openaire   +6 more sources

Evolutionary Origins and Virulence Determinants of ST25 Hypervirulent Klebsiella pneumoniae in Swine: Genomic Insights and Functional Validation

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The global spread of multidrug‐resistant hypervirulent Klebsiella pneumoniae (MDR‐HvKp), among which carbapenem‐resistant strains are of major concern, poses a severe threat to public health due to its high mortality rate and extremely limited treatment options.
Zheng Chen, Yang Liu, Congyang Du, Shengguo Gao, Lufeng Zhai, Stefan Schwarz, Weicheng Liu, Qiong Li, Longyu Li, Runhao Yu, Yuzhe Zhao, Hong Yao, Lei Luo, Xue Liu, Chunyan Xu, Xiang-Dang Du, Zongfu Wu   +16 more
wiley   +1 more source

No Experimental Evidence of Co-Feeding Transmission of African Swine Fever Virus between Ornithodoros Soft Ticks

Pathogens, 2020
Ornithodoros soft ticks are the only known vector and reservoir of the African swine fever virus, a major lethal infectious disease of Suidae. The co-feeding event for virus transmission and maintenance among soft tick populations has been poorly ...
Rémi Pereira De Oliveira, Evelyne Hutet, Maxime Duhayon, Frédéric Paboeuf, Marie-Frédérique Le Potier, Laurence Vial   +5 more
doaj   +1 more source