Results 81 to 90 of about 20,286 (224)

Cholesterol affects African swine fever virus infection [PDF]

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1998
African swine fever virus (ASFV) enters cells by receptor mediated endocytosis and requires a fusion event between the viral envelope and the limiting membrane of the endosome at low pH. In order to investigate the role of cholesterol in the early stages of ASFV infection, we have studied the effect of the removal of cell and viral membrane cholesterol
Bernardes, C., António, A., Pedroso de Lima, Maria C., Valdeira, M. L.   +3 more
openaire   +3 more sources

Emerging Challenges and Advances in Porcine Circovirus: A Decade in Review

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Over the past decade, porcine circoviruses (PCVs) have continued to pose a significant threat to global swine health, and pivotal discoveries have significantly reshaped our understanding of their biology and control. Extensive genomic surveillance has expanded porcine circovirus 2 (PCV2) genotyping from four to at least eight lineages, with PCV2d now ...
Jiawei Zheng, Guoqing Zhang, Peiheng Li, Linzhu Ren, Nan-hua Chen   +4 more
wiley   +1 more source

African swine fever virus assembles a single membrane derived from rupture of the endoplasmic reticulum [PDF]

, 2016
Collective evidence argues that two members of the nucleocytoplasmic large DNA viruses (NCLDVs) acquire their membrane from open membrane intermediates, postulated to be derived from membrane rupture.
Andrés, Germán, Hoppe, S., Kolovou, Androniki, Krijnse Locker, J., Salas, María Luisa, Suárez, Cristina, Walther, P.   +6 more
core   +1 more source

Structural insights into the DNA topoisomerase II of the African swine fever virus

Nature Communications
Type II topoisomerases are ubiquitous enzymes that play a pivotal role in modulating the topological configuration of double-stranded DNA. These topoisomerases are required for DNA metabolism and have been extensively studied in both prokaryotic and ...
Jingyuan Cong, Yuhui Xin, Huiling Kang, Yunge Yang, Chenlong Wang, Dongming Zhao, Xuemei Li, Zihe Rao, Yutao Chen   +8 more
doaj   +1 more source

Identification of a novel B-cell epitope of the African swine fever virus p34 protein and development of an indirect ELISA for the detection of serum antibodies

Frontiers in Microbiology
African swine fever (ASF) is a viral disease caused by the African swine fever virus that can be highly transmitted and lethal in domestic pigs. In the absence of a vaccine, effective diagnosis is critical for minimizing the virus’s spread.
Yuanyuan Tian, Yuanyuan Tian, Chao Liang, Chao Liang, Jingming Zhou, Jingming Zhou, Fanglin Sun, Fanglin Sun, Yankai Liu, Yankai Liu, Yumei Chen, Yumei Chen, Xifang Zhu, Xifang Zhu, Hongliang Liu, Hongliang Liu, Peiyang Ding, Peiyang Ding, Enping Liu, Enping Liu, Ying Zhang, Ying Zhang, Sixuan Wu, Sixuan Wu, Aiping Wang, Aiping Wang, Aiping Wang   +26 more
doaj   +1 more source

Insights into African swine fever virus immunoevasion strategies

Journal of Integrative Agriculture, 2020
African swine fever (ASF) is an acute and highly contagious disease that causes severe economic losses to the swine industry. ASF is caused by infection of African swine fever virus (ASFV) in domestic pigs, leading to almost 100% mortality.
Jun WANG, xin-jin SHI, Hai-wei SUN, Hong-jun CHEN   +3 more
doaj   +1 more source

Establishment and Evaluation of a Multicolor Latex Microsphere‐Based Lateral Flow Immunoassay for the Simultaneous Detection of Antibodies Against African and Classical Swine Fever Viruses

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
African swine fever (ASF), a highly fatal disease often termed the “number one killer” of pigs, presents clinical symptoms indistinguishable from classical swine fever (CSF), such as fever, diarrhea, and vomiting, complicating on‐site differential diagnosis.
Jie Chen, Zhengwang Shi, Yi Ru, Juncong Luo, Qianqian Yang, Yage Xie, Lin Wang, Jing Zhou, Xiaoyang Zhang, Juanjuan Wei, Yuqian Zhu, Hong Tian, Haixue Zheng, Nan-hua Chen   +13 more
wiley   +1 more source

Clinical and post-mortem signs in European wild boars and domestic pigs infected with African swine fever virus

Ветеринария сегодня, 2018
The paper covers comparative assessment of clinical and postmortem signs in wild boars and domestic pigs infected with one and the same epizootic isolate of African swine fever virus.
S. G. Remyga, A. S. Pershin, I. V. Shevchenko, A. S. Igolkin, A. A. Shevtsov   +4 more
doaj  

Recent Advances in Lateral Flow Immunoassay for Rapid Diagnosis of Viral Diseases

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Viral diseases are a major threat to human and animal health, as illustrated by recent pandemics like COVID‐19 and African swine fever (ASF). Timely, accurate detection of viral infections is critical for effective disease control. Among diverse diagnostic techniques, lateral flow immunoassay (LFIA) has become a widely used on‐site testing tool, owing ...
Quanyu Ren, Yan Wang, Haoyuan Ma, Jialiang Xie, Jianyou Jin, Rumeng Tian, Hao Yu, Xu Gao, Nanhua Chen   +8 more
wiley   +1 more source

A Novel In‐Cell ELISA With Superior Sensitivity and Specificity for the Detection of African Swine Fever Virus‐Specific IgM and IgG Antibodies

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
African swine fever (ASF), a high‐profile transboundary animal disease caused by ASF virus (ASFV), imposes a devastating impact on the global swine industry. Given that vaccines are still under development, including field evaluations, early detection of ASFV is crucial for effective disease control and mitigation.
Ping Wu, Aric J. McDaniel, Yelitza Y. Rodríguez, Vivian O’Donnell, Wei Jia, Nan-hua Chen   +5 more
wiley   +1 more source