Results 91 to 100 of about 1,681,802 (268)

Equine trypanosomiasis, a systematic review and meta‐analyses: Prevalence, morbidity and mortality

Equine Veterinary Journal, EarlyView.
Abstract Background Equine trypanosomiasis is a neglected protozoal disease. Objectives To perform a systematic search of literature to explore: (1) In equines what is the global geographical distribution and prevalence of trypanosomiasis? In low and middle‐income countries (LMICs) is trypanosomiasis more prevalent than in higher‐income countries (HICs)
Alexandra G. Raftery, Lauren Gummery, Karelhia Garcia, Dinesh Mohite, Paul Capewell, David G. M. Sutton   +5 more
wiley   +1 more source

Influence de la trypanosomose sur la reproduction des bovins en Afrique [PDF]

Tropicultura, 2000
The Influence of African Animal Trypanosomiasis on Reproduction of Cattle in Africa. The main effects of African animal Trypanosomiasis on reproduction of cattle have been reviewed.
Zecchini, M., Kageruka, P., De Deken, R.
doaj  

Village-scale persistence and elimination of gambiense human African trypanosomiasis

PLoS Neglected Tropical Diseases, 2019
Gambiense human African trypanosomiasis (gHAT) is one of several neglected tropical diseases that is targeted for elimination by the World Health Organization. Recent years have seen a substantial decline in the number of globally reported cases, largely
Christopher N. Davis, K. Rock, Erick Mwamba Miaka, M. Keeling   +3 more
semanticscholar   +1 more source

The structural, functional, and therapeutic potential of metacaspases in fungi and protozoa

The FEBS Journal, EarlyView.
Metacaspases are Ca2+‐dependent cysteine proteases whose structural characteristics, particularly calcium binding and autocatalytic processing, govern their activation and biological functions. These enzymes differ among microorganisms and regulate their cell cycles, making them excellent targets for drug development.
Ane C. M. Duarte, Mariana N. R. Trujilho, Karolaine S. S. M. Valdivia, Aline F. Araujo, Laura M. C. de Lorena, Vinicius H. de Oliveira, Beatriz V. Pereira, Emilly R. Leme, Wagner A. S. Júdice, Maurício F. M. Machado   +9 more
wiley   +1 more source

Independence from kinetoplast DNA maintenance and expression is associated with multi-drug resistance in Trypanosoma brucei in vitro [PDF]

, 2014
It is well known that several antitrypanosomatid drugs accumulate in the parasite's mitochondrion, where they often bind to the organellar DNA, the kinetoplast.
A. Schnaufer, Agbe, Bruhn, Brun, Cristodero, Dean, Deterding, Herbert, Hoare, Holmes, Kaminsky, Lai, Lanteri, M. K. Gould, Mathis, Mukherjee, Painter, Priest, Roy Chowdhury, Räz, Schnaufer, Schnaufer, Schnaufer, Shapiro, Stuart, Tang, Thuita, Ward, Wenzler, Wenzler, Wilson, Zhang, Zuma   +32 more
core   +1 more source

Trypanocidal and leishmanicidal activity of six limonoids [PDF]

, 2020
Six limonoids [kotschyienone A and B (1, 2), 7-deacetylgedunin (3), 7-deacetyl-7-oxogedunin (4), andirobin (5) and methyl angolensate (6)] were investigated for their trypanocidal and leishmanicidal activities using bloodstream forms of Trypanosoma ...
A-E Hay, AC Ivens, Bathelemy Ngameni, D Steverding, D Steverding, D Steverding, DAH Taylor, Dietmar Steverding, Evelyne Ollivier, G. Richard Stephenson, Gabriel N. Folefoc, GM Cragg, H Hirumi, J Mikus, K Merschjohann, Kevin M. Tyler, KM Ahua, Lazare S. Sidjui, LS Sidjui, PM Cheuka, S Nwaka, SE Atawodi, SJ Collins, T Baltz, Thomas E. Storr, Valérie Mahiou-Leddet, W Huber, W Ravangpai, Y-B Cheng, Éden Ramalho Ferreira, ÉR Ferreira   +30 more
core   +3 more sources

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

Journal of Microscopy, EarlyView.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz, Sara Silva Pereira, David Kirchenbuechler, Leandro Lemgruber, Constadina Arvanitis   +4 more
wiley   +1 more source

Green fluorescent diamidines as diagnostic probes for trypanosomes [PDF]

, 2014
LED fluorescence microscopy offers potential benefits to the diagnosis of human African trypanosomiasis, as well as to other aspects of diseases management, such as detection of drug resistant strains.
Arvind Kumar, Bailey, Baker, Barrett, Bieler, Bridges, Carter, Chappuis, David W. Boykin, de Koning, Federica Giordani, Hanscheid, Jones, Keiser, Lanteri, Manoj Munde, Mathis, Mathis, Matovu, Michael P. Barrett, Minion, Mohamed A. Ismail, Paine, Steingart, Stewart, Vincent, W. David Wilson, Wilson   +27 more
core   +1 more source

Generation of neuroinflammation in human African trypanosomiasis

Neurology: Neuroimmunology & Neuroinflammation, 2019
Human African trypanosomiasis (HAT) is caused by infection due to protozoan parasites of the Trypanosoma genus and is a major fatal disease throughout sub-Saharan Africa.
J. Rodgers, I. Steiner, P. Kennedy
semanticscholar   +1 more source

Ultrastructural expansion microscopy reveals unexpected levels of glycosome heterogeneity in African trypanosomes

Journal of Microscopy, EarlyView.
Abstract Kinetoplastid parasites include several species. Trypanosoma brucei causes African sleeping sickness in humans and a wasting disease nagana in livestock. Trypanosoma cruzi is the causative agent of Chagas disease and Leishmania species cause leishmaniasis, which can present with visceral, cutaneous, or mucocutaneous symptoms.
Heidi Anderson, Rhonda Reigers Powell, Meredith Teilhet Morris   +2 more
wiley   +1 more source