Results 81 to 90 of about 28,301 (202)
ABSTRACT Approaches integrating geospatial “big data” and machine learning will likely be increasingly used to predict conservation‐related human behavior, such as patterns of local engagement, in socioecological systems. Yet, few studies evaluate both the technical and ethical aspects of such applications.
Thomas Pienkowski +8 more
wiley +1 more source
Background Nagana (African Animal Trypanosomiasis-AAT) and tick-borne diseases (TBDs) constrain livestock production in most parts of sub-Saharan Africa.
Dennis Muhanguzi +10 more
doaj +1 more source
Current anti-trypanosomal therapies suffer from problems of longer treatment duration, toxicity and inadequate efficacy, hence there is a need for safer, more efficacious and ‘easy to use’ oral drugs.
Srinivasa P S Rao +13 more
doaj +1 more source
Equine trypanosomiasis, a systematic review and meta‐analyses: Prevalence, morbidity and mortality
Abstract Background Equine trypanosomiasis is a neglected protozoal disease. Objectives To perform a systematic search of literature to explore: (1) In equines what is the global geographical distribution and prevalence of trypanosomiasis? In low and middle‐income countries (LMICs) is trypanosomiasis more prevalent than in higher‐income countries (HICs)
Alexandra G. Raftery +5 more
wiley +1 more source
Anilinoquinoline based inhibitors of trypanosomatid proliferation.
We recently reported the medicinal chemistry re-optimization of a series of compounds derived from the human tyrosine kinase inhibitor, lapatinib, for activity against Plasmodium falciparum.
Lori Ferrins +11 more
doaj +1 more source
A Review of Infectious and Non‐Infectious Causes of Pregnancy Loss in Goats
ABSTRACT Goats play a vital role in global agriculture, particularly in developing regions, and are increasingly kept as companion animals. Given their economic and social importance, pregnancy losses in goats represent a substantial challenge, leading to considerable economic losses and raising concerns about animal welfare and public health, as some ...
Friederike Maria Kaus +4 more
wiley +1 more source
Cytotoxicity and Antimicrobial Activity of GaMF1 Analogs
GaMF1 is a reported, highly potent inhibitor of mycobacterial ATP synthase. Structural modification of this scaffold significantly changes biological activity. We present GaMF1 analogues with strong antiparasitic effects, potential antiproliferative properties, and discuss the selectivity limitations of the parent compound and its analogues.
Jan Chasák +8 more
wiley +1 more source
A murine model of Trypanosoma brucei-induced myocarditis and cardiac dysfunction
Trypanosoma brucei is a protozoan parasite that causes human and animal African trypanosomiases (HAT and AAT). Cardiac symptoms are commonly reported in HAT patients, and intracardiac parasites with accompanying myocarditis have been observed in both ...
Nathan P. Crilly +7 more
doaj +1 more source
Tsetse and trypanosomiasis (T&T) remain endemic in many countries, although many efforts have been made in recent decades within the framework of the Pan-African Tsetse and Trypanosomiasis Eradication Campaign (PATTEC) Initiative, and despite progress ...
Hassane H. Mahamat
doaj +1 more source

