Results 61 to 70 of about 1,412,769 (167)

A mathematical model for evaluating the role of trypanocide treatment of cattle in the epidemiology and control of Trypanosoma brucei rhodesiense and T. b. gambiense sleeping sickness in Uganda

Parasite Epidemiology and Control, 2019
Background: Human and animal African trypanosomiases impose a large economic and health burden in their endemic regions. Large strides have been made in the control of human African trypanosomiasis (HAT), yet these efforts have largely focused on the non-
Julianne Meisner, Ruanne V. Barnabas, Peter M. Rabinowitz   +2 more
doaj   +1 more source

Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

Advanced Science, Volume 13, Issue 59, 23 October 2026.
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa, Hui Yuan, Jingui Ma, Zhigang Yang, Mei Wang, Weibiao Wang, Lingling Yang, Fen Ma, Weiman Zhang, Gidion Wilson Mening'oo, Guoning Chen, Xueqin Ma   +11 more
wiley   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, Volume 7, Issue 5, October 2026.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Influence de la trypanosomose sur la reproduction des bovins en Afrique [PDF]

Tropicultura, 2000
The Influence of African Animal Trypanosomiasis on Reproduction of Cattle in Africa. The main effects of African animal Trypanosomiasis on reproduction of cattle have been reviewed.
Zecchini, M., Kageruka, P., De Deken, R.
doaj  

Community Health Workers' Multiple Understandings of Schistosomiasis Transmission Pathways: Exploring Contextual Factors in Côte d'Ivoire, Kenya and Uganda

Tropical Medicine &International Health, Volume 31, Issue 10, Page 1453-1464, October 2026.
ABSTRACT Objective Schistosomiasis remains a public health concern in sub‐Saharan Africa, affecting over 250 million people. In endemic settings, schistosomiasis transmission is not always understood exclusively in biomedical terms. Community health workers (CHWs) contribute to schistosomiasis control through mass drug administration and health ...
Dianne Verhoeven, Lisa Sophie Reigl, Alice Sereti Sinkeet, Mary Maghanga, Alexise Djouquou Gnahore, Bi Tra Jamal Sehi, Suzanne Lobohon Lavry, Andrea Buhl, Marie Frese, Jennifer Burrill, Eveline Hürlimann, Peter Steinmann, Nora Monnier, Ashley Preston, Janet Masaku, Matthias Richter, Mary Amuyunzu Nyamongo, Alain Toh, Stella Neema, Isabelle L. Lange, Andrea S. Winkler, on behalf of the Pediatric Praziquantel Consortium   +21 more
wiley   +1 more source

From sentinel surveillance for sleeping sickness treatment failure to the development of a pharmacovigilance approach [PDF]

, 2011
In the late 1990’s a disturbing trend of geographically distinct melarsoprol treatment failures accompanied a dramatic resurgence of Human African Trypanosomiasis.
Dahl, Benjamin Arthur
core   +1 more source

Untangling Inositol (Pyro)Phosphate Biology Through Emerging Technologies

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Inositol (pyro)phosphates represent a vital class of intracellular messengers that govern multiple biological processes. The last decade has experienced a surge of interest in the functions of this class of signaling molecules, primarily due to the introduction of several innovative analytical technologies.
Adolfo Saiardi, Mengsi Lu, Yue Zhang, Anuj Shukla, An‐Li Andrea Ko, Henning J. Jessen   +5 more
wiley   +1 more source

The natural progression of gambiense sleeping sickness: what is the evidence? [PDF]

, 2008
Gambiense human African trypanosomiasis (HAT, sleeping sickness) is widely assumed to be 100% pathogenic and fatal. However, reports to the contrary exist, and human trypano-tolerance has been postulated.
Filipe, João AN, Francesco Checchi, Barrett, M.P., Daniel Chandramohan, Checchi Francesco, Barrett, Michael P, Checchi, Francesco, Filipe, J.A.N., Chandramohan, Daniel, João A N Filipe, Barrett Michael P., Michael P Barrett, Filipe João A. N., Checchi, F., Chandramohan, D., Chandramohan Daniel   +15 more
core   +2 more sources

Survey of Smallholder Dairy Cattle Farming System and Antibiotic Residues in Raw Cow's Milk in Bagamoyo District, Tanzania

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Smallholder dairy farmers in Tanzania face livestock disease challenges that drive imprudent antimicrobial use and fuel antimicrobial resistance (AMR). In Bagamoyo, poor husbandry and limited disease control result in high prevalence of vector‐borne infections, commonly treated with oxytetracycline (OTC).
Ridhiwan I. Ramadhani, Hezron Emmanuel Nonga   +1 more
wiley   +1 more source

Stage progression and neurological symptoms in Trypanosoma brucei rhodesiense sleeping sickness: role of the CNS inflammatory response [PDF]

, 2012
Background: Human African trypanosomiasis progresses from an early (hemolymphatic) stage, through CNS invasion to the late (meningoencephalitic) stage.
MacLean, L., Peter G. E. Kennedy (126080), MacLean Lorna, Sternberg, J.M., Sternberg, Jeremy M, Peter G E Kennedy, Hansotto Reiber (126078), Sternberg Jeremy M., Reiber, H., Kennedy Peter G. E., Jeremy M Sternberg, Kennedy, Peter G E, Lorna MacLean, MacLean, Lorna, Lorna MacLean (126077), Jeremy M. Sternberg (126082), Reiber Hansotto, Kennedy, P.G.E., Reiber, Hansotto, Hansotto Reiber   +19 more
core   +1 more source