Results 51 to 60 of about 1,412,769 (167)

Disulfidptosis‐ and Ferroptosis‐Related Gene Signatures in Rheumatoid Arthritis: Association Analysis and Diagnostic Model Construction

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent synovial inflammation and progressive joint damage. Although ferroptosis has been implicated in RA progression, the role of disulfidptosis and its interaction with ferroptosis remains unclear.
Ting‐Ting Wang, Dong‐Mei Wang, Xue Li, Yuan‐Li Wei, Ping‐Dan Liu, Shi‐Lin Li, Si‐Ying Xiong, Cai‐Zhen Liu, Fan‐Xin Zeng, Jian‐Hong Wu, Lin Tang   +10 more
wiley   +1 more source

Chemotherapy of second stage human African trypanosomiasis : comparison between the parenteral diamidine DB829 and its oral prodrug DB868 in vervet monkeys [PDF]

, 2015
Human African trypanosomiasis (HAT, sleeping sickness) ranks among the most neglected tropical diseases based on limited availability of drugs that are safe and efficacious, particularly against the second stage (central nervous system [CNS]) of ...
Wang, Michael Z., Shelley Ching, Bridges, Arlene S., Bridges, Arlene S, Wang, Michael Z, Gem, Charles O, Michael Z Wang, Wolf, Kristina K, Wang, Michael Zhuo, Wolf, Kristina K., Ching, Shelley, Mutuku, James N., Arlene S Bridges, Boykin, David W, Murilla, Grace A, Murilla, Grace A., Qiang Liu, Paine, Mary F., Boykin, David W., Grace A Murilla, Jones, Susan K, Charles O Gem, James N Mutuku, Mary F Paine, Susan K Jones, Richard R Tidwell, Mutuku, James N, Paine, Mary F, David W Boykin, Liu, Qiang, Tidwell, Richard R., John K Thuita, Gem, Charles O., Kristina K Wolf, Jones, Susan K., Brun, Reto, Thuita, John K., Boykin, David, Reto Brun, Piane, Mary F., Tidwell, Richard R, Thuita, John K, Mutuku JN, Ching S, Wolf KK, Brun Reto, Mutuku James N., Bridges AS, Gem CO, Tidwell RR, Boykin DW, Paine MF, Bridges Arlene S., Ching Shelley, Murilla GA, Tidwell Richard R., Liu Q, Wang MZ, Boykin David W., Thuita JK, Gem Charles O., Liu Qiang, Jones SK, Jones Susan K., Brun R, Wang Michael Z., Murilla Grace A., Wolf Kristina K., Thuita John K., Paine Mary F.   +69 more
core   +2 more sources

The use of Multiple Displacement Amplification to increase the detection and genotyping of Trypanosoma samples immobilised on FTA filters. [PDF]

, 2007
Whole genome amplification methods are a recently developed tool for amplifying DNA from limited template. We report its application in trypanosome infections, characterized by low parasitemias.
Sweeney, L., Turner, C.M.R., Morrison, L.J., Likeufack, A.C.L., Truc, P., Tait, A., McCormack, G., MacLeod, A.   +7 more
core   +5 more sources

Challenges facing the elimination of sleeping sickness in west and central Africa: sustainable control of animal trypanosomiasis as an indispensable approach to achieve the goal

Parasites & Vectors, 2015
African trypanosomiases are infectious diseases caused by trypanosomes. African animal trypanosomiasis (AAT) remains an important threat for livestock production in some affected areas whereas human African trypanosomiasis (HAT) is targeted for ...
Gustave Simo, Jean Baptiste Rayaisse
doaj   +1 more source

Atlantic trade and the West African market economy: New evidence from cowry imports, 1650–1905

The Economic History Review, EarlyView.
Abstract Between the seventeenth and twentieth centuries, billions of cowries arrived in West Africa, leaving one of the few quantitative traces available for historians to measure the Atlantic trade's impact on the precolonial market economy. Yet, current estimates substantially underestimate the volume of cowry imports.
María José Pont Cháfer
wiley   +1 more source

Pharmacological investigations on current and new drugs for treatment of human African trypanosomiasis [PDF]

, 1999
Trypanosomiasis remains a major threat to humans in sub-Saharan Africa with 55-60 million people in 36 countries at risk of infection with T.b. gambiense or T.b. rhodesiense.
Keiser, Jennifer
core   +1 more source

HIV‐associated nephropathy: A decade of clinical outcomes, global disparities and emerging promise

HIV Medicine, EarlyView.
Abstract Objective To review the pathogenesis, epidemiology, clinical presentation, management and outcomes of HIV‐associated nephropathy (HIVAN), with emphasis on global disparities, genetic susceptibility (APOL1) and emerging therapeutic and technological advances.
Deepak V. Pathiyil, Nicola Wearne, Brendon Price, Frank Post, Dami A. Collier   +4 more
wiley   +1 more source

Local Solutions to Structural Issues: The Fetishization of Custom in Rural Development Interventions in Côte d'Ivoire

Journal of Agrarian Change, EarlyView.
ABSTRACT This paper explores the paradox of seeking local solutions in rural development when conflicts result from structural transformations of the agrarian economy driven by national political choices. Since the 1990s, participatory approaches inspired by neo‐institutionalist theories of local governance have encouraged development actors to view ...
Toni‐Giovanni Pegurri
wiley   +1 more source

Garlic‐Derived Behavioural Deterrents: Diallyl Disulfide and TrpA1‐Mediated Suppression of Insect Reproduction

Modern Agriculture, Volume 4, Issue 2, December 2026.
Garlic‐derived diallyl disulfide acts as a behavioural deterrent that suppresses insect mating and oviposition through sensory pathways. The compound is detected through gustatory mechanisms involving the transient receptor potential A1 (TrpA1) channel and neural responses.
Sumit Singh, Shaoying Wu
wiley   +1 more source

Prevalence of Human and Animal African Trypanosomiasis in Nigeria: A Scoping Review

Parasitologia
African trypanosomiasis is a protozoan disease that affects both humans and animals. Human African Trypanosomiasis (HAT) is a Neglected Tropical Disease targeted for elimination in 2030.
Chinwe Chukwudi, Elizabeth Odebunmi, Chukwuemeka Ibeachu   +2 more
doaj   +1 more source