Results 91 to 100 of about 1,412,769 (167)

Estimates of the duration of the early and late stage of gambiense sleeping sickness [PDF]

, 2008
Background: The durations of untreated stage 1 (early stage, haemo-lymphatic) and stage 2 (late stage, meningo-encephalitic) human African trypanosomiasis (sleeping sickness) due to Trypanosoma brucei gambiense are poorly quantified, but key to ...
Filipe, João AN, Haydon Daniel T, Filipe João AN, Chappuis, F., Checchi Francesco, Haydon, D.T., Checchi, F, Checchi, Francesco, Chandramohan, D, Chappuis, F, Chandramohan, Daniel, Filipe, J A N, Filipe, João A N., Haydon, Daniel T, Haydon, D T, Filipe, J.A., Haydon, Daniel T., Checchi, F., Chandramohan, D., Chappuis, François, Chappuis François, Chandramohan Daniel, Francesco Checchi, Daniel T Haydon, Daniel Chandramohan, João AN Filipe, François Chappuis   +26 more
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Computational Screening of Membrane Protein Epitopes for Vaccine Development Against Trypanosoma brucei 

Proceedings
Introduction: African trypanosomiasis is a fatal parasitic disease that affects both humans and animals [...]
Mariana Fochesato, Kayllany P. Santos, Maria E. L. Fernandes, Ytallo C. Sousa, Ygor Victor Ferreira Pinheiro, Leiz Maria Costa Véras   +5 more
doaj   +1 more source

Chemotherapy of Human African Trypanosomiasis

Interdisciplinary Perspectives on Infectious Diseases, 2009
Human Africa trypanosomiasis is a centuries-old disease which has disrupted sub-Saharan Africa in both physical suffering and economic loss. This article presents an update of classic chemotherapeutic agents, in use for >50 years and the recent ...
Cyrus J. Bacchi
doaj   +1 more source

Evaluation of the micro-CATT, CATT/Trypanosoma brucei gambiense, and LATEX/T. b. gambiense methods for serodiagnosis and surveillance of human African trypanosomiasis in West and Central Africa

Bulletin of the World Health Organization, 2002
OBJECTIVE: To evaluate the performance of serological tests using dried blood on filter-papers (micro-card agglutination test for trypanosomiasis (micro-CATT)) performed under field and laboratory conditions and using whole blood ((CATT/T.b.
Truc Philippe, Lejon Veerle, Magnus Eddy, Jamonneau Vincent, Nangouma Auguste, Verloo Didier, Penchenier Laurent, Büscher Philippe   +7 more
doaj  

Metabolomic profiling for the identification of drug targets in trypanosomes

Frontiers in Chemical Biology
Trypanosomes belong to a group of unicellular flagellated eukaryotes which include species responsible for serious, potentially fatal human diseases, mainly occurring in tropical and subtropical regions of the world: Trypanosoma brucei for sleeping ...
Maura Rojas-Pirela, Maura Rojas-Pirela, Maura Rojas-Pirela, Maura Rojas-Pirela, Diego Andrade-Alviárez, Wilfredo Quiñones, Ana J. Cáceres, Melisa Gualdrón-López, Ariel M. Silber, Ariel M. Silber, Paul A. M. Michels, Paul A. M. Michels   +11 more
doaj   +1 more source

Iloprost treatment enhanced IL-4 signalling to reverse trypanosome-induced cognitive deficits and suppressed neuroinflammation in mice

International Journal of Infectious Diseases
Introduction: The development of neurological disorders following trypanosome brain infection has been recognised for over a century. However, an ongoing endeavour persists to comprehensively understand the neurocognitive and neuropathological changes ...
Dr Oluwashola Olaolu, Professor Hajierah Davids, Professor Gill. B Dealtry, Miss Oluwatoyin Morenikeji, Dr Emmanuel T Obishakin, Mrs Binta Iliayasu, Dr Azeez Idris, Dr Chris Duyilemi Ajonijebu   +7 more
doaj   +1 more source

Programme for the Control of African Animal Trypanosomiasis and Related Development [PDF]

, 1985
Council of Ministers Forty-Second Ordinary Session 10 -16 July, 1985 Addis Ababa, EthiopiaThis report discusses the programme for the control of tsetse and trypanosomiasis, as part of the mandate received by the OAU in the Lagos Plan of Action to ...
Organization of African Unity
core   +1 more source

Africa and the Cattle Without History

Global Environment
African historiography of tsetse-borne trypanosomiasis has yet to fully embrace the genetic basis of cattle tolerance to the disease due to the literature’s emphasis on human illness and landscape modification.
Tad Brown
doaj   +1 more source

African trypanosomiasis gambiense, Italy.

, 2006
African trypanosomiasis caused by Trypanosoma brucei gambiense has not been reported in Italy. We report 2 cases diagnosed in the summer of 2004. Theses cases suggest an increased risk for expatriates working in trypanosomiasis-enclemic countries. Travel
Beltrame A, VIALE, PIERLUIGI, Bisoffi Z, Rorato G, Arzese A, Marocco S, Anselmi M, Monteiro G   +7 more
core   +1 more source

Research Approaches for the Discovery of Trypanocidal Molecular Prototypes from Plants

Natural Product Communications
In the absence of vaccines, chemotherapy remains a viable alternative for the control of African trypanosomiasis. To facilitate the eradication of African trypanosomiasis, there is the need to pay attention to the chemotherapeutic potential of secondary ...
Aboagye Kwarteng Dofuor
doaj   +1 more source