Results 11 to 20 of about 15,285 (33)

Field evaluation of the CATT/Trypanosoma brucei gambiense on blood-impregnated filter papers for diagnosis of human African trypanosomiasis in southern Sudan. [PDF]

, 2002
Most Human African Trypanosomiasis (HAT) control programmes in areas endemic for Trypanosoma brucei gambiense rely on a strategy of active mass screening with the Card Agglutination Test for Trypanosomiasis (CATT)/T. b. gambiense.
Adams, K, Bovier, P A, Büscher, P, Chappuis, F, Godineau, V, Hwang, S Y, Magnus, E, Pittet, A   +7 more
core   +2 more sources

Delineating neuroinflammation, parasite CNS invasion, and blood-brain barrier dysfunction in an experimental murine model of human African trypanosomiasis [PDF]

, 2017
Although Trypanosoma brucei spp. was first detected by Aldo Castellani in CSF samples taken from sleeping sickness patients over a century ago there is still a great deal of debate surrounding the timing, route and effects of transmigration of the ...
Bradley, Barbara, Kennedy, Peter G.E., Rodgers, Jean   +2 more
core   +1 more source

Management of trypanosomiasis and leishmaniasis [PDF]

, 2012
<p>Background: The current treatments for human African trypanosomiasis (HAT), Chagas disease and leishmaniasis (collectively referred to as the kinetoplastid diseases) are far from ideal but, for some, there has been significant recent progress ...
Alsford, Alvar, Alvar, Barrett, Barrett, Ben Salah, Berman, Bern, Brun, Brun, Burri, Chappuis, Coura, Croft, Croft, El-Sayed, Frearson, Hailu, Jacobs, Jacobs, Le Loup, Lessa, M. P. Barrett, Miranda-Verastegui, Paine, Pinazo, Priotto, Rassi, Reithinger, Rodgers, S. L. Croft, Stuart, Sundar, Sundar, Sundar, Sundar, Torreele, Vanhollebeke, Vincent, Voogd   +39 more
core   +2 more sources

Insights from quantitative and mathematical modelling on the proposed 2030 goal for gambiense human African trypanosomiasis (gHAT) [PDF]

, 2019
Gambiense human African trypanosomiasis (gHAT) is a parasitic, vector-borne neglected tropical disease that has historically affected populations across West and Central Africa and can result in death if untreated.
Aliee, Maryam, Antillon, Marina, Chitnis, Nakul, Crump, Ronald E., Davis, Christopher, HASH(0x55cde5a53b80), Huang, Ching-I, Keeling, Matt J., Rock, Kat S., Soledad Castaño, María, Tediosi, Fabrizio   +10 more
core   +1 more source

Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis [PDF]

, 2009
Human African trypanosomiasis, or sleeping sickness, is caused by the protozoan parasites <i>Trypanosoma brucei rhodesiense</i> or <i>Trypanosoma brucei gambiense</i>, and is a major cause of systemic and neurological disability ...
Adams, B. Bradley, Clark, Eastman, Eastman, Giles, Gonzalez, Guidetti, Hirumi, J. Rodgers, Jennings, Jennings, Jhamandas, Kamleh, Kennedy, Kennedy, Kennedy, Kennedy, M. P. Barrett, Moffett, Okuda, Okuda, P. G. E. Kennedy, Pepin, Perkins, Pfefferkorn, P  pin, R  z, Sanni, Schroten, Schwarcz, Smith, Sternberg, Stone, Stone, Stone, T. W. Stone, Vincendeau   +37 more
core   +2 more sources

Eflornithine is Safer Than Melarsoprol for the Treatment of Second-Stage Trypanosoma Brucei Gambiense Human African Trypanosomiasis. [PDF]

, 2005
Patients with second-stage human African trypanosomiasis treated with eflornithine (n = 251) in 2003 in Kiri, southern Sudan, had an adjusted relative risk of death of 0.2 and experienced significantly fewer cutaneous and neurological adverse effects ...
A. Meussen, Brun, F. Chappuis, K. Stietenroth, Legros, Milord, Milord, N. Udayraj, P. A. Bovier, P  pin, Schmid   +10 more
core   +2 more sources

Integrated cost-benefit analysis of tsetse control and herd productivity to inform control programs for animal African trypanosomiasis [PDF]

, 2018
Animal African trypanosomiasis (AAT) and its tsetse vector are responsible for annual losses estimated in billions of US dollars ($). Recent years have seen the implementation of a series of multinational interventions.
Chilongo, K, Fauron, A, Gilbert, W, Guitian, J, Holt, H R, Meyer, A, Mumba, C, Oumarou,, F   +7 more
core   +1 more source

Spatially and genetically distinct African trypanosome virulence variants defined by host interferon-g response [PDF]

, 2007
We describe 2 spatially distinct foci of human African trypansomiasis in eastern Uganda. The Tororo and Soroti foci of <i>Trypanosoma brucei rhodesiense</i> infection were genetically distinct as characterized by 6 microsatellite and 1 ...
Anneli Cooper, Annette MacLeod, Bakhiet M, Bancroft GJ, Cattand P, Hertz CJ, Hunter CA, Jeremy M. Sternberg, Liam Morrison, Lindsay Sweeney, Lorna MacLean, Martin Odiit, Morrison LJ, Page RDM, Peter G. E. Kennedy, Schleifer KW, Schleifer KW, Sternberg JM, Woo PT, World Health Organization   +19 more
core   +1 more source

African trypanosomiasis in travelers returning to the United Kingdom. [PDF]

, 2002
Two returning safari tourists with African trypanosomiasis were admitted to the Hospital for Tropical Diseases, London, in a 3-day period, compared with six cases in the previous 14 years.
Agranoff, Dan, Bailey, J Wendi, Chiodini, Peter L, Edwards, Mark, Escombe, Rod, Moore, David AJ, Squire, S Bertel   +6 more
core   +2 more sources

Human African trypanosomiasis amongst urban residents in Kinshasa: a case-control study. [PDF]

, 2004
BACKGROUND: Increasing numbers of human African trypanosomiasis (HAT) cases have been reported in urban residents of Kinshasa, Democratic Republic Congo since 1996. We set up a case-control study to identify risk factors for the disease.
Bilengue CM, Burke J, Dupont WD, Gouteux JP, Gouteux JP, Grebaut P, Magnus E, Meda AH, Mulumba PM, Noireau F, Okia M, Van Hoof L., Van Nieuwenhove S, Watsenga TN, World Health Organisation, Wyatt GB   +15 more
core   +4 more sources