Results 11 to 20 of about 1,681,802 (268)

Insights into the Control and Management of Human and Bovine African Trypanosomiasis in Zambia between 2009 and 2019—A Review

Tropical Medicine and Infectious Disease, 2020
Tsetse transmitted trypanosomiasis is a fatal disease commonly known as Nagana in cattle and sleeping sickness in humans. The disease threatens food security and has severe economic impact in Africa including most parts of Zambia.
Gloria M. Mulenga, Lars Henning, Kalinga Chilongo, Chrisborn Mubamba, Boniface Namangala, Bruce Gummow   +5 more
doaj   +2 more sources

Human African trypanosomiasis : the current situation in endemic regions and the risks for non-endemic regions from imported cases [PDF]

Parasitology, 2020
Human African trypanosomiasis (HAT) is caused by Trypanosoma brucei gambiense and T. b. rhodesiense and caused devastating epidemics during the 20th century. Due to effective control programs implemented in the last two decades, the number of reported
Gao, J-M, Hide, G, Lai, D-H, Lun, Z-R, Qian, Z-Y, Wu, Z-D   +5 more
core   +3 more sources

APOL1 renal risk variants have contrasting resistance and susceptibility associations with African trypanosomiasis

eLife, 2017
Reduced susceptibility to infectious disease can increase the frequency of otherwise deleterious alleles. In populations of African ancestry, two apolipoprotein-L1 (APOL1) variants with a recessive kidney disease risk, named G1 and G2, occur at high ...
Anneli Cooper, Hamidou Ilboudo, V Pius Alibu, Sophie Ravel, John Enyaru, William Weir, Harry Noyes, Paul Capewell, Mamadou Camara, Jacqueline Milet, Vincent Jamonneau, Oumou Camara, Enock Matovu, Bruno Bucheton, Annette MacLeod   +14 more
doaj   +2 more sources

Evaluation of the micro-CATT, CATT/Trypanosoma brucei gambiense, and LATEX/T. b. gambiense methods for serodiagnosis and surveillance of human African trypanosomiasis in West and Central Africa

Bulletin of the World Health Organization, 2002
OBJECTIVE: To evaluate the performance of serological tests using dried blood on filter-papers (micro-card agglutination test for trypanosomiasis (micro-CATT)) performed under field and laboratory conditions and using whole blood ((CATT/T.b.
Truc Philippe, Lejon Veerle, Magnus Eddy, Jamonneau Vincent, Nangouma Auguste, Verloo Didier, Penchenier Laurent, Büscher Philippe   +7 more
doaj   +2 more sources

Anti-Trypanosomal Proteasome Inhibitors Cure Hemolymphatic and Meningoencephalic Murine Infection Models of African Trypanosomiasis

Tropical Medicine and Infectious Disease, 2020
Current anti-trypanosomal therapies suffer from problems of longer treatment duration, toxicity and inadequate efficacy, hence there is a need for safer, more efficacious and ‘easy to use’ oral drugs.
Srinivasa P S Rao, Suresh B Lakshminarayana, Jan Jiricek, Marcel Kaiser, Ryan Ritchie, Elmarie Myburgh, Frantisek Supek, Tove Tuntland, Advait Nagle, Valentina Molteni, Pascal Mäser, Jeremy C Mottram, Michael P Barrett, Thierry T Diagana   +13 more
doaj   +2 more sources

Chalcogen Derivatives for the Treatment of African Trypanosomiasis: Biological Evaluation of Thio- and Seleno-Semicarbazones and Their Azole Derivatives. [PDF]

ACS Omega
Rubio-Hernández M, Teixeira TR, Nguyen TP, Shingyoji M, da Silva EB, O'Donoghue AJ, Caffrey CR, Pérez-Silanes S, Martínez-Sáez N.   +8 more
europepmc   +4 more sources

Chemotherapy of Human African Trypanosomiasis [PDF]

Interdisciplinary Perspectives on Infectious Diseases, 2009
Human Africa trypanosomiasis is a centuries-old disease which has disrupted sub-Saharan Africa in both physical suffering and economic loss. This article presents an update of classic chemotherapeutic agents, in use for >50 years and the recent ...
Cyrus J. Bacchi
doaj   +2 more sources

Human African Trypanosomiasis (Sleeping Sickness)-Epidemiology, Clinical Manifestations, Diagnosis, Treatment, and Prevention. [PDF]

Curr Trop Med Rep, 2023
Ortiz-Martínez Y, Kouamé MG, Bongomin F, Lakoh S, Henao-Martínez AF.   +4 more
europepmc   +2 more sources

Focus–Specific Clinical Profiles in Human African Trypanosomiasis Caused by Trypanosoma brucei rhodesiense [PDF]

, 2010
<p><b>Background:</b> Diverse clinical features have been reported in human African trypanosomiasis (HAT) foci caused by <i>Trypanosoma brucei rhodesiense</i> (<i>T.b.rhodesiense</i>) giving rise to the ...
Lorna MacLean, Martin Odiit, John Chisi, Peter G. E. Kennedy, J. Sternberg   +4 more
openalex   +8 more sources

Notes from the Field: Rhodesiense Human African Trypanosomiasis (Sleeping Sickness) in a Traveler Returning from Zimbabwe - United States, August 2024. [PDF]

MMWR Morb Mortal Wkly Rep
Wendt EM, Tobolowsky FA, Priotto G, Franco JR, Chancey R.   +4 more
europepmc   +3 more sources