Results 21 to 30 of about 16,753 (222)

Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis [PDF]

, 2009
Human African trypanosomiasis, or sleeping sickness, is caused by the protozoan parasites <i>Trypanosoma brucei rhodesiense</i> or <i>Trypanosoma brucei gambiense</i>, and is a major cause of systemic and neurological disability ...
Barrett, M.P., Stone, T.W., Bradley, B.M., Kennedy, P.G.E., Rodgers, J.   +4 more
core   +1 more source

Tsetse distribution, trypanosome infection rates, and small-holder livestock producers’ capacity enhancement for sustainable tsetse and trypanosomiasis control in Busia, Kenya

Tropical Medicine and Health, 2020
Background Tsetse flies are the cyclical vectors of both human and animal diseases. Kenya’s commitment to eradicate tsetse and trypanosomiasis dates to the 1980s through various control approaches which were spearheaded by the African Union.
Ferdinard Adungo, Tom Mokaya, Olipher Makwaga, Matilu Mwau   +3 more
doaj   +1 more source

Towards the Atlas of human African trypanosomiasis [PDF]

, 2009
Background Updated, accurate and comprehensive information on the distribution of human African trypanosomiasis (HAT), also known as sleeping sickness, is critically important to plan and monitor control activities.
Cecchi Giuliano, Simarro Pere P, Fevre, Eric M., Mattioli, Raffaele C., Ruíz, J.A., Franco José R, Cecchi, Giuliano, Raffaele C Mattioli, Abdoulaye Diarra, Paone, M., José R Franco, Mattioli Raffaele C, Ruiz, Jose A., Diarra, A., Paone, Massimo, Diarra, Abdoulaye, Paone Massimo, Massimo Paone, Franco, Jose R., José A Ruiz, Diarra Abdoulaye, Eric M Fèvre, Simarro, Pere P., Pere P Simarro, Fèvre Eric M, Franco, J.R., Cecchi, G., Giuliano Cecchi, Ruiz José A   +28 more
core   +1 more source

Plant Terpenoids as Hit Compounds against Trypanosomiasis

Pharmaceuticals, 2022
Human African trypanosomiasis (sleeping sickness) and American trypanosomiasis (Chagas disease) are vector-borne neglected tropical diseases, caused by the protozoan parasites Trypanosoma brucei and Trypanosoma cruzi, respectively.
Raquel Durão, Cátia Ramalhete, Ana Margarida Madureira, Eduarda Mendes, Noélia Duarte   +4 more
doaj   +1 more source

Focus–specific clinical profiles in human African trypanosomiasis caused by Trypanosoma brucei rhodesiense [PDF]

, 2010
<p><b>Background:</b> Diverse clinical features have been reported in human African trypanosomiasis (HAT) foci caused by <i>Trypanosoma brucei rhodesiense</i> (<i>T.b.rhodesiense</i>) giving rise to the ...
Odiit, Martin, Martin Odiit, Sternberg, J.M., Sternberg, Jeremy M, Peter G E Kennedy, MacLean, Lorna M, Chisi, J.E., Chisi, John, Peter G. E. Kennedy, Lorna M MacLean, Jeremy M Sternberg, John E. Chisi, Odiit, M., Kennedy, Peter, Kennedy, P.G.E., Jeremy M. Sternberg, Lorna M. MacLean, John E Chisi, MacLean, L.M.   +18 more
core   +1 more source

Systematic Review and Meta-Analysis on Knowledge Attitude and Practices on African Animal Trypanocide Resistance

Tropical Medicine and Infectious Disease, 2022
Background: African trypanocide resistance is an emerging public health emergency whose control requires a revisit on farmer’s knowledge, attitudes, and practices in developing countries.
Keneth Iceland Kasozi, Ewan Thomas MacLeod, Charles Waiswa, Michael Mahero, Ibrahim Ntulume, Susan Christina Welburn   +5 more
doaj   +1 more source

A literature review of economic evaluations for a neglected tropical disease : human African trypanosomiasis ("sleeping sickness") [PDF]

, 2015
Human African trypanosomiasis (HAT) is a disease caused by infection with the parasite Trypanosoma brucei gambiense or T. b. rhodesiense. It is transmitted to humans via the tsetse fly.
Sutherland, C. S., Joshua Yukich, Tediosi, F., C. Simone Sutherland (689448), C Simone Sutherland, Ron Goeree (201687), Fabrizio Tediosi (247282), TEDIOSI, FABRIZIO, Ron Goeree, Goerre, R., Yukich, Joshua, Sutherland, C. Simone, Yukich, J., C. Simone Sutherl, Fabrizio Tediosi, Joshua Yukich (44606), Goeree, Ron   +16 more
core   +1 more source

APOL1 renal risk variants have contrasting resistance and susceptibility associations with African trypanosomiasis

eLife, 2017
Reduced susceptibility to infectious disease can increase the frequency of otherwise deleterious alleles. In populations of African ancestry, two apolipoprotein-L1 (APOL1) variants with a recessive kidney disease risk, named G1 and G2, occur at high ...
Anneli Cooper, Hamidou Ilboudo, V Pius Alibu, Sophie Ravel, John Enyaru, William Weir, Harry Noyes, Paul Capewell, Mamadou Camara, Jacqueline Milet, Vincent Jamonneau, Oumou Camara, Enock Matovu, Bruno Bucheton, Annette MacLeod   +14 more
doaj   +1 more source

Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis [PDF]

, 2011
Human African trypanosomiasis (HAT), or sleeping sickness, results from infection with the protozoan parasites <i>Trypanosoma brucei</i> (<i>T.b.</i>) <i>gambiense</i> or <i>T.b.rhodesiense</i> and is ...
Jones, A., Michael P. Barrett, Peter G E Kennedy, Bradley Barbara, Bradley, Barbara, Barrett, M. P., McCabe Christopher, Peter G. E. Kennedy, Bradley, B., Rodgers, Jean, Gettinby, George, Gettinby George, Kennedy Peter G. E., McCabe, Chris, Amy Jones, Kennedy, Peter G. E., Barrett, Michael P., Michael P Barrett, Kennedy, Peter G.E., George Gettinby, Gibaud, Stephane, Barbara Bradley, McCabe, C., Mccabe, Christopher, Jean Rodgers, Kennedy, P. G. E., Gibaud, S., Stéphane Gibaud, Rodgers, J., Rodgers Jean, Jones Amy, Jones, Amy, Christopher McCabe, Barrett Michael P., Gibaud Stéphane, Gettinby, G.   +35 more
core   +1 more source

Prevalence and under-detection of gambiense human African trypanosomiasis during mass screening sessions in Uganda and Sudan [PDF]

, 2012
BACKGROUND: Active case detection through mass community screening is a major control strategy against human African trypanosomiasis (HAT, sleeping sickness) caused by T. brucei gambiense.
Haydon Daniel T, Chappuis, F., Cox, A.P., Cox Andrew P, Checchi Francesco, Haydon, D.T., Priotto Gerardo, Priotto, Gerardo, Checchi, Francesco, Chandramohan, Daniel, Priotto, G., Haydon, Daniel T, Cox, Andrew P, Checchi, F., Chandramohan, D., Chappuis, François, Chappuis François, Chandramohan Daniel   +17 more
core   +1 more source