Tropical Medicine and Infectious Disease, 2020 Tsetse transmitted trypanosomiasis is a fatal disease commonly known as Nagana in cattle and sleeping sickness in humans. The disease threatens food security and has severe economic impact in Africa including most parts of Zambia.
Gloria M. Mulenga +5 more
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A molecular mechanism for eflornithine resistance in African trypanosomes [PDF]
, 2010 Human African trypanosomiasis, endemic to sub-Saharan Africa, is invariably fatal if untreated. Its causative agent is the protozoan parasite Trypanosoma brucei.
Creek, Darren +7 more
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Virulence, 2023 African trypanosomes are vector-borne protozoa, which cause significant human and animal disease across sub-Saharan Africa, and animal disease across Asia and South America.
Liam J. Morrison +3 more
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Identification of sVSG117 as an immunodiagnostic antigen and evaluation of a dual-antigen lateral flow test for the diagnosis of human african trypanosomiasis [PDF]
, 2014 The diagnosis of human African trypanosomiasis (HAT) caused by Trypanosoma brucei gambiense relies mainly on the Card Agglutination Test for Trypanosomiasis (CATT). There is no immunodiagnostic for HAT caused by T. b. rhodesiense.
Sastry Lalitha +20 more
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Transmission concomitante de trypanosomose humaine et animale : le foyer de Mandoul au Tchad
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2014 La trypanosomose est une maladie qui affecte à la fois l’homme et les animaux. Elle est provoquée par Trypanosoma sp. et cycliquement transmise par un vecteur, la glossine.
Peka Mallaye +4 more
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Accuracy of five algorithms to diagnose gambiense human African trypanosomiasis. [PDF]
, 2011 Algorithms to diagnose gambiense human African trypanosomiasis (HAT, sleeping sickness) are often complex due to the unsatisfactory sensitivity and/or specificity of available tests, and typically include a screening (serological), confirmation ...
Francesco Checchi +19 more
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Computer-aided identification of Trypanosoma brucei uridine diphosphate galactose 4'-epimerase inhibitors : toward the development of novel therapies for African sleeping sickness [PDF]
, 2010 Trypanosoma brucei, the causative agent of human African trypanosomiasis, affects tens of thousands of sub-Saharan Africans. As current therapeutics are inadequate due to toxic side effects, drug resistance, and limited effectiveness, novel therapies are
Durrant, Jacob D. +3 more
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African trypanosomiasis in travelers returning to the United Kingdom. [PDF]
, 2002 Two returning safari tourists with African trypanosomiasis were admitted to the Hospital for Tropical Diseases, London, in a 3-day period, compared with six cases in the previous 14 years.
Bailey, J Wendi +17 more
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Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis [PDF]
, 2009 Human African trypanosomiasis, or sleeping sickness, is caused by the protozoan parasites <i>Trypanosoma brucei rhodesiense</i> or <i>Trypanosoma brucei gambiense</i>, and is a major cause of systemic and neurological disability ...
Barrett, M.P. +4 more
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The history of African trypanosomiasis
Parasites & Vectors, 2008 The prehistory of African trypanosomiasis indicates that the disease may have been an important selective factor in the evolution of hominids. Ancient history and medieval history reveal that African trypanosomiasis affected the lives of people living in
Steverding Dietmar
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