Mechanisms controlling anaemia in Trypanosoma congolense infected mice. [PDF]
, 2009 Trypanosoma congolense are extracellular protozoan parasites of the blood stream of artiodactyls and are one of the main constraints on cattle production in Africa.
A Kobayashi +74 more
core +3 more sources
MIF contributes to Trypanosoma brucei associated immunopathogenicity development [PDF]
, 2014 African trypanosomiasis is a chronic debilitating disease affecting the health and economic well-being of many people in developing countries. The pathogenicity associated with this disease involves a persistent inflammatory response, whereby M1-type ...
Beschin, Alain +11 more
core +4 more sources
Infections with extracellular trypanosomes require control by efficient innate immune mechanisms and can result in the destruction of the mammalian humoral immune system [PDF]
, 2020 Salivarian trypanosomes are extracellular parasites that affect humans, livestock, and game animals around the world. Through co-evolution with the mammalian immune system, trypanosomes have developed defense mechanisms that allow them to thrive in blood,
Magez, Stefan +3 more
core +1 more source
Eflornithine is a cost-effective alternative to melarsoprol for the treatment of second-stage human West African trypanosomiasis in Caxito, Angola. [PDF]
, 2008 OBJECTIVE: To compare the cost-effectiveness of eflornithine and melarsoprol in the treatment of human African trypanosomiasis. METHOD: We used data from a Médecins Sans Frontières treatment project in Caxito, Angola to do a formal cost-effectiveness ...
Adam +23 more
core +2 more sources
Screening strategies for a sustainable endpoint for Gambiense sleeping sickness [PDF]
, 2020 Background. Gambiense human African trypanosomiasis (gHAT, sleeping sickness) is a vector-borne disease typically fatal without treatment. Intensified, mainly medical-based, interventions in endemic areas have reduced the occurrence of gHAT to ...
Aliee, Maryam +5 more
core +2 more sources
Updated estimate of the duration of the meningo-encephalitic stage in gambiense human African trypanosomiasis [PDF]
, 2015 Background: The duration of the stages of HAT is an important factor in epidemiological studies and intervention planning. Previously, we published estimates of the duration of the haemo-lymphatic stage 1 and meningo-encephalitic stage 2 of the ...
Chandramohan, Daniel +4 more
core +2 more sources
Plasma neuronal specific enolase : a potential stage diagnostic marker in human African trypanosomiasis [PDF]
, 2014 © The Author 2014. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
Mitchell, Julia A, Sternberg, Jeremy M
core +1 more source
T. brucei cathepsin-L increases arrhythmogenic sarcoplasmic reticulum-mediated calcium release in rat cardiomyocytes [PDF]
, 2013 Aims: African trypanosomiasis, caused by Trypanosoma brucei species, leads to both neurological and cardiac dysfunction and can be fatal if untreated. While the neurological-related pathogenesis is well studied, the cardiac pathogenesis remains unknown ...
Abdulla +36 more
core +2 more sources
Molecular identification of different trypanosome species and subspecies in tsetse flies of northern Nigeria [PDF]
, 2016 Background: Animal African Trypanosomiasis (AAT) is caused by several species of trypanosomes including Trypanosoma congolense, T. vivax, T. godfreyi, T. simiae and T. brucei. Two of the subspecies of T. brucei also cause Human African Trypanosomiasis.
Ciosi, Marc +8 more
core +1 more source
Trypanosoma (Duttonella) vivax: Its biology, epidemiology, pathogenesis, and introduction in the New World - a review [PDF]
, 2008 The biology, epidemiology, pathogenesis, diagnostic techniques, and history of the introduction of Trypanosoma (Duttonella) vivax in the New World are reviewed.
Desquesnes, Marc +5 more
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