Results 51 to 60 of about 12,732 (210)

Pandemic Prevention Paradigms: Understanding Global Health Governance

Public Health Challenges, Volume 4, Issue 2, June 2025.
One Health is an emerging area of integrative studies and interventions aimed at preventing zoonotic diseases by addressing human, animal, and environmental interactions. A fundamental aspect of the concept is understanding how these interactions influence health outcomes among humans, animals, and ecosystems. Developed initially to respond to the need
Soheil Sadr, Cinzia Santucciu, Valentina Chisu, Narges Lotfalizadeh, Shakiba Nazemian, Negin Esfandiari, Ashkan Hajjafari, Helia Sepahvand, Abbas Rahdar, Sadanand Pandey, Hassan Borji   +10 more
wiley   +1 more source

African animal trypanosomiasis as a constraint to livestock health and production in Karamoja region: a detailed qualitative and quantitative assessment

BMC Veterinary Research, 2017
Background Nagana (African Animal Trypanosomiasis-AAT) and tick-borne diseases (TBDs) constrain livestock production in most parts of sub-Saharan Africa.
Dennis Muhanguzi, Albert Mugenyi, Godfrey Bigirwa, Maureen Kamusiime, Ann Kitibwa, Grace Gloria Akurut, Sylvester Ochwo, Wilson Amanyire, Samuel George Okech, Jan Hattendorf, Robert Tweyongyere   +10 more
doaj   +1 more source

Anti-Trypanosomal Proteasome Inhibitors Cure Hemolymphatic and Meningoencephalic Murine Infection Models of African Trypanosomiasis

Tropical Medicine and Infectious Disease, 2020
Current anti-trypanosomal therapies suffer from problems of longer treatment duration, toxicity and inadequate efficacy, hence there is a need for safer, more efficacious and ‘easy to use’ oral drugs.
Srinivasa P S Rao, Suresh B Lakshminarayana, Jan Jiricek, Marcel Kaiser, Ryan Ritchie, Elmarie Myburgh, Frantisek Supek, Tove Tuntland, Advait Nagle, Valentina Molteni, Pascal Mäser, Jeremy C Mottram, Michael P Barrett, Thierry T Diagana   +13 more
doaj   +1 more source

A Primate APOL1 Variant That Kills Trypanosoma brucei gambiense. [PDF]

PLoS Neglected Tropical Diseases, 2016
Humans are protected against infection from most African trypanosomes by lipoprotein complexes present in serum that contain the trypanolytic pore-forming protein, Apolipoprotein L1 (APOL1).
Anneli Cooper, Paul Capewell, Caroline Clucas, Nicola Veitch, William Weir, Russell Thomson, Jayne Raper, Annette MacLeod   +7 more
doaj   +1 more source

Perceived Threat of Zoonotic Infections in Abattoir Workers in the Tamale Metropolis of Ghana: An Assessment of Knowledge, Attitudes and Practices

Public Health Challenges, Volume 4, Issue 2, June 2025.
Most abattoir workers (90.2%) knew that humans can get zoonotic diseases from the animals they handle. However, some respondents believe that witchcraft (20.0%), curses (20.8%) and supernatural powers (18.0%) cause zoonotic diseases. ABSTRACT Background Abattoir workers are more prone to acquiring zoonotic diseases.
Benjamin Nuhu Tingbani, Ezekiel Kofi Vicar, Stephen Apanga, Elijah Bisuman Sambian, Samuel Tamanyian Suuk, Edmond Nakinpaak Biibantib, Williams Walana   +6 more
wiley   +1 more source

AFRICAN TRYPANOSOMIASIS [PDF]

Journal of the American Medical Association, 1915
Patient. —I. S., No. 181943, man, negro, aged 35, native of Cape Verde Islands, was admitted to the Massachusetts State Infirmary from New Bedford, Oct. 7, 1914. The patient was unable to understand English, and as a good Portuguese interpreter was not available at the time, his history could not be obtained.
openaire   +3 more sources

Regulator experiences of trials during Ebola epidemics in Sierra Leone, Guinea, and the Democratic Republic of the Congo

Tropical Medicine &International Health, Volume 30, Issue 6, Page 539-546, June 2025.
Abstract Introduction During the 2014–2016 Ebola epidemic in West Africa and the Ebola outbreaks between 2018 and 2020 in the Democratic Republic of Congo, vaccines and other tools for prevention and treatment had to be taken through trials in exceptional circumstances using accelerated processes.
Kambale Kasonia, Frank Baiden, Frédéric Le Marcis, Bruno Lapika, Joel Kiyulu, Henri Kimina, Freddy Bikioli, Fanny Attas, Anthony Mansaray, Rose Burns, Elysée Nouvet, Séverine Thys, Antea Paviotti, Daniela Manno, Mukeh Kenneth Fahnbulleh, Bailah Leigh, Mohamed Samai, Brian Greenwood, Shelley Lees, Patrick Mitashi Mulopo, Deborah Watson‐Jones   +20 more
wiley   +1 more source

Risk Evaluation and Mitigation Strategies for Newly Detected Mysterious Dinga Dinga Virus Infection in Africa: A Narrative Review

Health Science Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Background and Aims The Dinga Dinga Virus (DDV) has emerged as a mysterious disease gripping women in Uganda, raising alarm due to its unusual and distressing “dancing” like symptoms. These symptoms, characterized by involuntary movements resembling dance, suggest possible neurological involvement, though the exact pathogen remains ...
Sabrina Sharmin, Salsabil Islam, Md. Aminul Haque, Md. Rabiul Islam   +3 more
wiley   +1 more source

Host genetics in African trypanosomiasis

Infection, Genetics and Evolution, 2008
In Africa, the protozoan parasite of the genus Trypanosoma causes animal (AAT) and human African trypanosomiasis (HAT). These diseases are responsible for considerable mortality and economic losses, and until now the drugs commonly used have often been very toxic and expensive, with no vaccine available.
Courtin, D., Berthier, D., Thevenon, S., Dayo, G. K., /Garcia, André, /Bucheton, Bruno   +5 more
openaire   +5 more sources

A murine model of Trypanosoma brucei-induced myocarditis and cardiac dysfunction

Microbiology Spectrum
Trypanosoma brucei is a protozoan parasite that causes human and animal African trypanosomiases (HAT and AAT). Cardiac symptoms are commonly reported in HAT patients, and intracardiac parasites with accompanying myocarditis have been observed in both ...
Nathan P. Crilly, Marcelle Dina Zita, Alexander K. Beaver, Polina Sysa-Shah, Aashik Bhalodia, Kathy Gabrielson, Luigi Adamo, Monica R. Mugnier   +7 more
doaj   +1 more source