mBio, 2021 African trypanosomiasis is a neglected tropical disease caused by the parasitic protozoan Trypanosoma bruceiT.
Anuj Tripathi +7 more
doaj +1 more source
Nanobodies as tools to understand, diagnose, and treat African trypanosomiasis [PDF]
, 2017 African trypanosomes are strictly extracellular protozoan parasites that cause diseases in humans and livestock and significantly affect the economic development of sub-Saharan Africa.
Caljon, Guy +5 more
core +1 more source
African Trypanosomiasis Dynamics: Modelling the Effects of Treatment, Education, and Vector Trapping
International Journal of Mathematics and Mathematical Sciences, 2020 African trypanosomiasis is a vector-borne disease that is mainly transmitted by infected tsetse flies. A deterministic model of tsetse fly vector, human, and cattle hosts is formulated and analyzed to gain insights into the disease dynamics. The roles of
Y. Liana +3 more
semanticscholar +1 more source
Human African trypanosomiasis caused by Trypanosoma brucei gambiense: The first case report in China
International Journal of Infectious Diseases, 2019 We report the first imported case in China of human African trypanosomiasis (HAT), caused by Trypanosoma brucei gambiense, in a sailor returning from Gabon in 2014.
Nian Chen +4 more
doaj +1 more source
Delineating neuroinflammation, parasite CNS invasion, and blood-brain barrier dysfunction in an experimental murine model of human African trypanosomiasis [PDF]
, 2017 Although Trypanosoma brucei spp. was first detected by Aldo Castellani in CSF samples taken from sleeping sickness patients over a century ago there is still a great deal of debate surrounding the timing, route and effects of transmigration of the ...
Bradley, Barbara +2 more
core +1 more source
Clinical and Neuropathogenetic Aspects of Human African Trypanosomiasis
Frontiers in Immunology, 2019 Trypanosomiasis has been recognized as a scourge in sub-Saharan Africa for centuries. The disease, caused by protozoan parasites of the Trypanosoma genus, is a major cause of mortality and morbidity in animals and man. Human African trypanosomiasis (HAT),
P. Kennedy, J. Rodgers
semanticscholar +1 more source
Repurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis
bioRxiv, 2020 Tsetse transmit African trypanosomiasis, which is a disease fatal to both humans and animals. A vaccine to protect against this disease does not exist so transmission control relies on eliminating tsetse populations.
M. Sterkel +17 more
semanticscholar +1 more source
Clinical management of East African trypanosomiasis in South Africa: Lessons learned
International Journal of Infectious Diseases, 2018 Background: East African trypanosomiasis is an uncommon, potentially lethal disease if not diagnosed and treated in a timely manner. South Africa, as a centre for emergency medical evacuations from much of sub-Saharan Africa, receives a high proportion ...
John Frean +4 more
doaj +1 more source
Frontiers in Tropical DiseasesHuman African trypanosomiasis (HAT), commonly known as sleeping sickness, remains a significant health threat in sub-Saharan Africa. In Nigeria, the challenges of diagnosing and treating HAT are profound, especially in resource-constrained, remote areas.
Kelly Zongo, Rolayo Toyin Emmanuel
doaj +1 more source
Molecular epidemiological studies on animal trypanosomiases in Ghana
Parasites & Vectors, 2012 Background African trypanosomes are extracellular protozoan parasites that are transmitted between mammalian hosts by the bite of an infected tsetse fly. Human African Trypanosomiasis (HAT) or sleeping sickness is caused by Trypanosoma brucei rhodesiense
Nakayima Jesca +5 more
doaj +1 more source