Results 61 to 70 of about 174,156 (175)

STUDIO COMPUTAZIONALE DI VIRTUAL SCREENING PER LO SVILUPPO DI NUOVI INBITORI DELLA CHINASI BTK [PDF]

, 2014
La BTK (Bruton’s Tyrosine Kinase) è un membro della famiglia delle tirosine chinasi TEC. La BTK è espressa in molte cellule ematopoietiche come linfociti B, nei mastociti, e nei macrofagi, ma non è espressa a livello dei linfociti T, nelle cellule ...
PICCINNO, MARIA ELEONORA
core  

Btk Regulated Macrophage Polarization in Response to Lipopolysaccharide [PDF]

, 2014
Bacterial Lipopolysaccharide (LPS) is a strong inducer of inflammation and does so by inducing polarization of macrophages to the classic inflammatory M1 population.
Brennan, Kiva, Byrne, Jennifer C., Hams, Emily, Kissenpfennig, Adrien, Ní Gabhann, Joan, Smith, Siobhán, Spence, Shaun, Wynne, Claire   +7 more
core   +1 more source

Decoding Ca2+ signals: a question of timing [PDF]

Receptor-stimulated Ca2+ signals come in several flavors. The Ca2+ signals can be decoded linearly or by integration of the response. How the duration of the signal conveyed by cytosolic Ca2+ concentration ([Ca2+]i) changes is regulated is not well ...
Muallem, Shmuel
core   +2 more sources

A novel mutation leading to a deletion in the SH3 domain of Bruton's tyrosine kinase [PDF]

, 2006
X-linked agammaglobulinemia (XLA) is a primary B cell immunodeficiency disorder, caused by a defect in the Bruton tyrosine kinase (BTK) gene. Here, we describe a novel four base pair mutation (838delGAGT) in intron 9 of the BTK gene leading to the ...
Fügen Ersoy, Hilal Ozdag, Ilhan Tezcan, Lütfiye Mesci, Ozden Sanal, Tuba Turul   +5 more
core   +1 more source

B cells at the crossroad of immune responses : insights from primary B-cell immunodeficiencies [PDF]

, 2012
Tese de doutoramento, Ciências Biomédicas (Imunologia), Universidade de Lisboa, Faculdade de Medicina, 2012B lymphocytes are important players in adaptive immunity and the main targets of current vaccination strategies, with the interaction between B and
Barbosa, Rita R., 1982-
core  

Fatal X-linked agammaglobulinemia complicated by septic shock: a case report and comprehensive review of novel BTK mutations. [PDF]

Front Immunol
Wu P, You W, Liu W, Luo N, Xu J.
europepmc   +1 more source

Bronchiectasis and deteriorating lung function in agammaglobulinaemia despite immunoglobulin replacement therapy

Clinical and Experimental Immunology, 2018
A. Stubbs, C. Bangs, B. Shillitoe, J. Edgar, S. Burns, M. Thomas, H. Alachkar, M. Buckland, E. McDermott, G. Arumugakani, M. S. Jolles, R. Herriot, P. Arkwright   +12 more
semanticscholar   +1 more source

Real-world treatment patterns of Bruton tyrosine kinase inhibitors in mantle cell lymphoma in a community oncology setting. [PDF]

Future Oncol
Shah BD, Xue M, Furnback W, Yang K.
europepmc   +1 more source

Case Report: Preserved umbilical cords underscore family histories of inborn errors of immunity. [PDF]

Front Immunol
Nishimura M, Tomomasa D, Suzuki R, Miyaoka F, Kanegane H.   +4 more
europepmc   +1 more source

Resistance Mutations in CLL: Genetic Mechanisms Shaping the Future of Targeted Therapy. [PDF]

Genes (Basel)
Sekeres S, Lamkin EN, Bravo E, Cool A, Taylor J.   +4 more
europepmc   +1 more source