Results 31 to 40 of about 18,093 (282)

A Patient with X-Linked Agammaglobulinemia and COVID-19 Infection Treated with Remdesivir and Convalescent Plasma

Journal of Clinical Immunology, 2021
To the Editor: Over the past year, the coronavirus disease 2019 (COVID19) has resulted in a worldwide pandemic. The disease results in a wide range of clinical presentations that range from asymptomatic to respiratory failure and death. To date, only two
Aled Iaboni, N. Wong, S. Betschel
semanticscholar   +1 more source

Gastrointestinal Manifestations in X-linked Agammaglobulinemia

Journal of Clinical Immunology, 2017
Sara Barmettler, Roshini S Abraham, Zuhair K Ballas   +2 more
exaly   +2 more sources

Optimizing Integration and Expression of Transgenic Bruton's Tyrosine Kinase for CRISPR-Cas9-Mediated Gene Editing of X-Linked Agammaglobulinemia

The CRISPR Journal, 2021
X-linked agammaglobulinemia (XLA) is a monogenic primary immune deficiency characterized by very low levels of immunoglobulins and greatly increased risks for recurrent and severe infections.
David Gray, Isaac Villegas, Joseph D. Long, Jasmin L. Santos, A. Keir, Alison Abele, C. Kuo, D. Kohn   +7 more
semanticscholar   +1 more source

Genetic diagnosis of patients with primary agammaglobulinemia treated at third level peruvian centers

Revista Peruana de Medicina Experimental y Salud Pública, 2019
Primary agammaglobulinemia result from specific alterations in B cells, which lead to low antibody production. Diagnostic suspicion is established with a history of repeated infections, low immunoglobulins, and absence of CD19+ B lymphocytes.
Edgar Matos-Benavides, David Garcia-Gomero, Rosario Inocente-Malpartida, Wilmer Córdova-Calderón, Juan Aldave-Becerra   +4 more
doaj   +1 more source

Deletion within the Src homology domain 3 of Bruton's tyrosine kinase resulting in X-linked agammaglobulinemia (XLA). [PDF]

, 1994
The gene responsible for X-linked agammaglobulinemia (XLA) has been recently identified to code for a cytoplasmic tyrosine kinase (Bruton's agammaglobulinemia tyrosine kinase, BTK), required for normal B cell development. BTK, like many other cytoplasmic
Chen, SH, Hagemann, T, Kwan, SP, Nilsson, L, Ochs, HD, Rawlings, DJ, Saffran, DC, Smith, CI, Vihinen, M, Witte, ON, Zhang, M, Zhu, Q   +11 more
core   +1 more source

Agammaglobulinemia

New England Journal of Medicine, 1955
Richard L. Varco, Lloyd D. MacLean, J. Bradley Aust, Robert A. Good   +3 more
openaire   +3 more sources

IgM Augments Complement Bactericidal Activity with Serum from a Patient with a Novel CD79a Mutation [PDF]

, 2018
Antibody replacement therapy for patients with antibody deficiencies contains only IgG. As a result, concurrent IgM and IgA deficiency present in a large proportion of antibody deficient patients persists.
Burg, M. (Mirjam) van der, Flier, M. (Michiel) van der, Henriet, S.S.V. (Stefanie S.V.), Jonge, M.I. (Marien) de, Kuipers, S. (Saskia), Langereis, J.D. (Jeroen), Weemaes, C.M.R. (Corry)   +6 more
core   +1 more source

Late diagnosis of agammaglobulinemia in an 8-year-old boy

Pediatria i Medycyna Rodzinna, 2016
Chromosome X-linked Bruton agammaglobulinemia is classified as a primary immunodeficiency disorder. It is a genetic condition associated with a mutation in the BTK gene encoding tyrosine kinase.
Małgorzata Sopińska, Karolina Kapusta, Edyta Heropolitańska-Pliszka, Anna Jung, Bolesław Kalicki   +4 more
doaj   +1 more source

Subcutaneous IgG Replacement Therapy by Push in 32 Patients with Primary Immunodeficiency Diseases in Argentine [PDF]

, 2014
Introduction: Regular replacement with immunoglobulin infusions is the mainstay of treatment in the majority of primary immunodeficiencies. Several studies showed that Subcutaneous Immunoglobulin (SCIG) has similar efficacy to Intravenous Immunoglobulin (
Bezrodnik, Liliana, Díaz Ballve, Damacia, Giovanni, Daniela Di, Gómez Raccio, Andrea, Moreira, Ileana, Regairaz, Lorena, Seminario, Gisela   +6 more
core   +1 more source

Mutations of Bruton's tyrosine kinase gene in Brazilian patients with X-linked agammaglobulinemia [PDF]

, 2010
Mutations in Bruton's tyrosine kinase (BTK) gene are responsible for X-linked agammaglobulinemia (XLA), which is characterized by recurrent bacterial infections, profound hypogammaglobulinemia, and decreased numbers of mature B cells in peripheral blood.
OLIVEIRA JÚNIOR, E.B., RAMALHO, V.D., ROXO JÚNIOR, P., TANI, S.M., VILELA, M.M.S.   +4 more
core   +2 more sources