Results 71 to 80 of about 28,912 (281)
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Theory of pixel lensing towards M31 I: the density contribution and mass of MACHOs
, 2000 POINT-AGAPE is an Anglo-French collaboration which is employing the Isaac Newton Telescope (INT) to conduct a pixel-lensing survey towards M31. In this paper we investigate what we can learn from pixel-lensing observables about the MACHO mass and ...
Carr, B. J. +8 more
core +2 more sources
Detection of CO in the inner part of M31's bulge [PDF]
, 2000 We report the first detection of CO in M31's bulge. The 12CO (1-0) and (2-1) lines are both detected in the dust complex D395A/393/384, at 1.3" (~0.35 kpc) from the centre.
Guelin, M. +3 more
core +3 more sources
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Actitudes hacia el amor en relaciones románticas de jóvenes universitarios
Praxis & Saber, 2017 El presente estudio muestra un análisis de identificación de las tipologías del amor más sobresalientes en las relaciones de pareja, a través de la Escala de Actitudes Amorosas (Hendrick y Hendrick), la cual explora los seis tipos de amor propuestos por ...
Brenda Liz Rocha Narváez +3 more
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Recensión: Jacob Buganza-Rafael Cúnsulo, Breve esquema de antropología filosófica
Studium: Filosofía y Teología, 2013 Jacob Buganza-Rafael Cúnsulo, Breve esquema de antropología filosófica, Buenos Aires, Ágape, 2012, 176 pp.
Mauricio Beuchot
doaj +1 more source
Understanding the experience of discovering a kindred spirit connection: a phenomenological study [PDF]
, 2012 Preliminary existential-hermeneutic phenomenological analysis of data based on 24 protocols, and our own reflexive discussion, reveals how “kindred spirit connections” manifest in myriad elusive, evocative ways.
Eatough, Virginia, Finlay, L.
core