Results 71 to 80 of about 18,303,252 (310)

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Age-Related Macular Degeneration: Classification and Pathogenesis

, 2014
Age-related macular degeneration (AMD) was first described in 1885 by Otto Haab as a disease in patients above 50 years of age with progressive retinal pigment epithelial and atrophic degenerations of the macula reducing the central visual acuity.
İmren Akkoyun
core   +1 more source

Age-related decrease in motor cortical inhibition during standing under different sensory conditions [PDF]

, 2014
BackgroundAlthough recent studies point to the involvement of the primary motor cortex in postural control, it is unknown if age-related deterioration of postural control is associated with changes in motor cortical circuits.
Hortobágyi, Tibor, Taube, Wolfgang, Stéphane eBaudry, Tibor eHortobágyi, Tibor Hortobágyi, Hortobagyi, Tibor; id_orcid, Margot Hogenhout, Wolfgang eTaube, Stéphane Baudry, Baudry, Stéphane, Margot eHogenhout, Selma Papegaaij, Wolfgang Taube, Selma ePapegaaij, Papegaaij, Selma, Hogenhout, Margot, Baudry S, Taube W, Hortobágyi T, Papegaaij S, Hogenhout M   +20 more
core   +1 more source

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source

Metabolic reprogramming via SIRT2-deficient microglial large extracellular vesicles ameliorates alzheimer’s pathology

Journal of Neuroinflammation
Background Current therapies for Alzheimer’s disease (AD) offer only symptomatic relief, highlighting the urgent need for disease-modifying approaches capable of halting or reversing neurodegeneration.
Xiaolu Tang, Rui Chen, Jiawei Xing, Qing Huang, Lv Luo, Chaoyue Ouyang, Fubin Ma, Jie Wen, Jiahao Zhang, Lingyun Kong, Yujie Cai, Yan Wang, Lili Cui   +12 more
doaj   +1 more source

A randomized, double-masked, placebo controlled clinical trial of multivitamin supplementation for age-related lens opacities. Clinical trial of nutritional supplements and age-related cataract report n° 3

, 2008
OBJECTIVE: To evaluate the effect of a multivitamin/mineral supplement on development or progression of age-related lens opacities. DESIGN: Randomized, double-masked, single center, placebo-controlled clinical trial.
Ferrigno L., supplements, CAMPARINI, Monica, Sperduto RD, Rosmini F, Maraini G, Ferris F, Clinical Trial of nutritional, age related cataract STUDY GROUP, Clemons TE   +9 more
core  

Profiling age-related epigenetic markers of stomach adenocarcinoma in young and old subjects [PDF]

, 2015
The purpose of our study is to identify epigenetic markers that are differently expressed in the stomach adenocarcinoma (STAD) condition. Based on data from The Cancer Genome Atlas (TCGA), we were able to detect an age-related difference in methylation ...
Kim, Byoung-Chul, Byung Pal Yu, Park, Daeui, Bhak, Jong Hwa, Jeong, Hyoung Oh, Eunok Im, Sunghoon Lee, Kim, Nam Deuk, Hae Young Chung, Chung, Hae Young, Jong Bhak, Lee, Eun Kyeong, Lee, Sunghoon, Kim, Chul-Hong, Yu, Byung Pal, Eun Kyeong Lee, Im, Eunok, Nam Deuk Kim, Chul-Hong Kim, Hyoung Oh Jeong, Daeui Park, Dae Hyun Kim, Byoung-Chul Kim, Kim, Dae Hyun   +23 more
core   +1 more source

“We Cannot Talk as a Family”: Complexities of Survivorship Communication Among Hispanic/Latino Young Adult Survivors of Childhood Cancer, Parents, and Clinicians

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu, Nicole Fernández‐Viña, Briana C. Martin‐Villa, Daniela Ramirez, Rebecca M. Lewinsohn, Mary Smith, Heidi Boynton, Lidia Schapira, Stephanie M. Smith   +8 more
wiley   +1 more source

The estimated prevalence and incidence of late stage age related macular degeneration in the UK [PDF]

, 2012
BACKGROUND: UK estimates of age related macular degeneration (AMD) occurrence vary. AIMS: To estimate prevalence, number and incidence of AMD by type in the UK population aged ≥50 years.
Fletcher, AE, Owen, CG, Rudnicka, AR, Fletcher, Astrid E, Rudnicka, Alicja R, Jarrar, Z, Cook, DG, Wormald, Richard, Wormald, R, Owen, Christopher G, Jarrar, Zakariya, Cook, Derek G   +11 more
core   +1 more source

Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham, Teyl Engstrom, Peter Baade, Natalie Bradford, Sarah Pont, Louise Marquart‐Wilson, Natasha Nassar, Jason D. Pole   +7 more
wiley   +1 more source