Results 191 to 200 of about 121,313 (254)

Resolving a Complex Neonatal Phenotype by Rapid Trio Whole‐Genome Sequencing: A De Novo 11q14.3–q22.3 Deletion and a Splicing‐Altering Synonymous ANK1 Variant

Journal of Clinical Laboratory Analysis, EarlyView.
Clinical utility of trio WGS and time metrics in a neonate with congenital anomalies and hemolytic anemia. ABSTRACT Background Neonates with complex and evolving phenotypes often lack sufficiently specific clinical features to guide targeted genetic testing.
Hyun‐Woo Lee, Ja‐Hyun Jang, Beom Hee Lee, Hee‐Jeong Youk, Eun Sun Kim, Kee Hyun Cho, Yun Sil Chang, Heui Seung Jo, Mi‐Ae Jang   +8 more
wiley   +1 more source

The role of HDAC11 in age-related hearing loss: Mechanisms and therapeutic implications. [PDF]

Open Life Sci
Guan L, Chen J, Jiang H.
europepmc   +1 more source

Reward Deficits in Co‐Occurring Social Anxiety and Depression: The Roles of Anhedonia, Boredom, Loneliness, and COVID‐19 Social Restriction

Journal of Clinical Psychology, EarlyView.
ABSTRACT Prior research points toward reward deficits as crucial to the link between social anxiety disorder and major depressive disorder. However, studies have not explored specific types of reward deficits or how social‐environmental factors may impact them. The current study examined whether the indirect effects of three reward deficits (anhedonia,
Nathan M. Hager, Alicia L. Milam, Hannah C. Hamrick, Benjamin Swanson, Matt R. Judah   +4 more
wiley   +1 more source

Age-related hearing loss and balance disorders: analysis of interactions and clinical implications in older persons. Systematic review and meta-analysis. [PDF]

Front Aging
Frosolini A, Franz L, Calvanese L, Caragli V, Parrino D, Fabbris C, Badin G, Negrisolo M, Cenedese R, Doretto L, Brescia G, de Filippis C, Genovese E, Zanoletti E, Marioni G.   +14 more
europepmc   +1 more source

Prenatal exposure to antihypertensive medication: A systematic review of neurodevelopmental and educational outcomes

JCPP Advances, EarlyView.
This systematic review investigated the association of prenatal exposure to antihypertensive medication with longer‐term poor neurodevelopmental outcomes by evaluating the findings from existing literature. We undertook a systematic review of previous studies looking specifically at neurodevelopmental outcomes in children.
Shrifah Alkhalaf, Sarjit Singh, Jill P. Pell, Scott M. Nelson, Daniel F. Mackay, Michael Fleming   +5 more
wiley   +1 more source

From genomic discovery to application in age-related hearing loss: a global bibliometric and cross-ethnic analysis. [PDF]

Front Aging Neurosci
Lu Y, Shen J, Sou KHK, Lu H, Huang S, Uus K.   +5 more
europepmc   +1 more source

Developing an integrated algorithm to support autism diagnostic decisions: Model performance and statistical fairness

JCPP Advances, EarlyView.
Abstract Background Best practices in diagnosing autism spectrum disorder require an expert diagnostician to integrate multiple sources of information, including direct observations, interviews, and rating scales completed by knowledgeable informants.
Aaron J. Kaat, Ashlynn Campagna, Hannah Feiner, Jeffrey Michael Grauzer, Amanda Nicole Hobson, Maranda Jones, Jordan Paige Lee, Laura Jean Sudec, Megan York Roberts   +8 more
wiley   +1 more source

Histopathological change of age-related hearing loss in female advance-aged CBA/CaJ mice. [PDF]

PLoS One
Inuzuka Y, Mizutari K, Kurioka T, Suzuki J, Koizumi Y, Araki K, Shiotani A.   +6 more
europepmc   +1 more source

Family and friends perspectives on communication barriers and patient social isolation in Canadian hospitals

Journal of Hospital Medicine, EarlyView.
Abstract Background Hospitalization can disrupt patients’ communication and social connections, potentially contributing to social isolation, while the supportive role of family and friends in communication is often underrecognized. Objective This study examines communication access barriers and their association with social isolation among ...
Sama Amirkhani‐Ardeh, Sasha Wade, Emma Rossnagel, Aderonke Agboji, Davina Banner, Trina Fyfe, Tammy Klassen‐Ross, Shannon Freeman   +7 more
wiley   +1 more source

Cochlear endoplasmic reticulum stress causes connexin 26 degradation is involved in age-related hearing loss. [PDF]

iScience
Bai X, Liao B, Hu WH, Wang MQ, Sun Y, Chen XB, Xu K.   +6 more
europepmc   +1 more source