Results 111 to 120 of about 207,426 (323)

Progression of Age-Related Macular Degeneration Among Individuals Homozygous for Risk Alleles on Chromosome 1 (CFH-CFHR5) or Chromosome 10 (ARMS2/HTRA1) or Both [PDF]

open access: hybrid, 2022
Steffen Schmitz-Valckenberg   +10 more
openalex   +1 more source

Cloud‐Based GWAS Platform: An Innovative Solution for Efficient Acquisition and Analysis of Genomic Data

open access: yesMed Research, EarlyView.
This graphical abstract illustrates the cloud‐based GWAS platform as a hub that integrates six major multiomics domains: phenomics, neuroscience, proteomics, microbiomics, metabolomics, and nutrigenomics. The platform unifies diverse data types—including clinical phenotypes, neuroimaging, plasma proteomics, microbiome profiles, metabolic biomarkers ...
Xiaohong Ke   +12 more
wiley   +1 more source

Hyperreflective Material Boundary Remodeling in Neovascular Age-Related Macular Degeneration

open access: hybrid, 2023
Siqing Yu   +7 more
openalex   +2 more sources

Abnormal Serum Lipid Levels and Ocular Metabolic Mediators in Adult‐Onset Myopia: A Cohort Study

open access: yesMedicine Advances, EarlyView.
Elevated levels of “good cholesterol” markers apolipoprotein A (APOA) and high‐density lipoprotein cholesterol (HDL‐C) were prospectively associated with an increased risk of developing adult‐onset myopia, whereas higher levels of “bad cholesterol” markers apolipoprotein B (APOB) and low‐density lipoprotein cholesterol (LDL‐C) were associated with a ...
Feipeng Jiang   +9 more
wiley   +1 more source

Understanding the Impact of the Sirtuin 1 (SIRT1) Gene on Age-related Macular Degeneration: A Comprehensive Study

open access: yesNigerian Postgraduate Medical Journal
Age-related macular degeneration (AMD) is a prevalent and incurable condition affecting the central retina and posing a significant risk to vision, particularly in individuals over the age of 60.
Saranya Velmurugan   +4 more
doaj   +1 more source

Stimuli‐responsive systems: A focus on controlled drug delivery for posterior segment ocular disease

open access: yesResponsive Materials, EarlyView.
This review highlights recent advances in stimuli‐responsive drug delivery for posterior segment diseases, focusing on mechanisms and potential. It also explores mechanically interlocked molecules and bioorthogonal reactions as novel approaches. Challenges and future perspectives are discussed, aiming to bridge the gap between research and clinical ...
Chengzhi Zhang   +11 more
wiley   +1 more source

Transcriptome changes in age-related macular degeneration

open access: yesBMC Medicine, 2012
Age-related macular degeneration (AMD) is a debilitating, common cause of visual impairment. While the last decade has seen great progress in understanding the pathophysiology of AMD, the molecular changes that occur in eyes with AMD are still poorly ...
Whitmore S Scott, Mullins Robert F
doaj   +1 more source

Emerging applications of rare‐earth fluoride nanocrystals in medicine and biotechnologies

open access: yesResponsive Materials, EarlyView.
Rare‐earth fluoride nanocrystals (REFNCs) exhibit high responsivity and can be used as multi‐modal agents in medicine and theranostics. This review summarizes recent advances in REFNCs, covering their synthesis, structures, luminescent properties, and applications in multi‐modal imaging and photodynamic therapy, highlighting their theranostic potential
Alain Tressaud   +3 more
wiley   +1 more source

Alterations in the Choriocapillaris in Intermediate Age-Related Macular Degeneration [PDF]

open access: gold, 2017
Enrico Borrelli   +3 more
openalex   +1 more source

Bidirectional Associations Between Seborrheic Dermatitis and Epithelial Barrier Diseases: A Retrospective Cohort Study

open access: yesAllergy, EarlyView.
This study explores the bidirectional associations between SD and EBDs in a cohort of 5,083,689 individuals in a US administrative claims database. Positive bidirectional associations were found between SD and many EBDs of the skin, respiratory, gastrointestinal, and ocular surfaces. Our results support the EBT as a shared driver of EBD pathogenesis at
Sabrina Meng   +6 more
wiley   +1 more source

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