Results 291 to 300 of about 205,027 (361)

CD59, Disulphide‐Locked Human C9 and Horse C9 Inhibit Human Membrane Attack Complex Assembly by Similar Mechanisms

Immunology, Volume 176, Issue 3, Page 363-372, November 2025.
The membrane attack complex (MAC) is formed by the stepwise assembly of five proteins: C5b, C6, C7, C8 and C9. MAC plays a key role in driving inflammation in numerous diseases. This study compares the inhibitory mechanisms of MAC assembly by soluble CD59 (sCD59), a disulphide‐locked C9 mutant (C9lock) and horse C9 (HoC9).
Rebekah S. Cooke, Bradley A. Spicer, Richard A. Harrison, Michelle A. Dunstone, B. Paul Morgan, Wioleta M. Zelek   +5 more
wiley   +1 more source

Identifying the important involvement of cuproptosis in the pathophysiology of age-related macular degeneration. [PDF]

Eur J Med Res
Lei S, Liu Y.
europepmc   +1 more source

Prevention of age related macular degeneration

, 2002
Nigel F. Hall
openalex   +2 more sources

Quantitative analysis of human umbilical vein endothelial cell morphology and tubulogenesis

Journal of Microscopy, Volume 300, Issue 2, Page 234-249, November 2025.
Abstract Primary human umbilical vein endothelial cells can grow as both a monolayer in culture and also as a capillary‐like network making them an ideal model system in order to study vascular remodelling. Image‐based analysis can allow assessment of cell morphology and motility but is dependent on accurate cell segmentation which requires high ...
Viviane Mignone, Maria Augusta Arruda, Laura Kilpatrick, Benjamin Moore, Jeanette Woolard, Stephen Hill, Joëlle Goulding   +6 more
wiley   +1 more source

Pharmacotherapy for Age-Related Macular Degeneration

Journal of Ophthalmic & Vision Research, 2008
Hamid Ahmadieh
doaj  

Early-onset macular drusen, a monogenic form of age-related macular degeneration. [PDF]

Am J Ophthalmol Case Rep
George LM, Ranjana M, Quinodoz M, Tang RWC, Lim WK, Gilhar NG, Farooqui SZ, Rivolta C, Fenner BJ.   +8 more
europepmc   +1 more source

Treatment of age-related macular degeneration

The Lancet, 2013
Chui Ming Gemmy Cheung, Tien Yin Wong
openaire   +3 more sources

Pigment Epithelium‐Derived Factor (PEDF)‐Based Therapy Induced Photoreceptor Survival by Stabilizing Choroidal Neovessels in a VEGF Overexpression CNV Rat Model

The FASEB Journal, Volume 39, Issue 19, 15 October 2025.
Stabilizing choroidal neovessels offers a novel treatment‐option for pathological CNV. Pigment epithelium‐derived factor (PEDF), a multifunctional protein with vessel‐stabilizing properties, is a promising candidate for this approach. Its efficacy with and without bevacizumab was tested in a VEGF overexpression CNV rat model.
Alexander V. Tschulakow, Lei Xi, Ulrich Schraermeyer, Sylvie Julien   +3 more
wiley   +1 more source

Smoking-Attributable Age-Related Macular Degeneration Vision Loss in China: 1990-2021 Trends and 2040 Projections. [PDF]

Transl Vis Sci Technol
Huang L, Hu P, Chen J, Liu J, Grzybowski A.   +4 more
europepmc   +1 more source

Faculty Opinions recommendation of Aberrant accumulation of EFEMP1 underlies drusen formation in Malattia Leventinese and age-related macular degeneration.

, 2002
Darryl Nishimura
openalex   +2 more sources