Results 131 to 140 of about 9,169,898 (343)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Características do uso de métodos anticoncepcionais no Estado de São Paulo

open access: yesRevista de Saúde Pública
OBJETIVO: Analisar dados coletados pela Pesquisa Nacional de Demografia e Saúde, de 1996, sobre o uso de métodos anticoncepcionais no Estado de São Paulo, Brasil.
Elisabeth Meloni Vieira   +3 more
doaj  

Gender And Age Peculiarities Of Tobacco Addiction Among The Urban Population Of The Middle Volga Region [PDF]

open access: yesСаратовский научно-медицинский журнал, 2009
On the basis of the conducted research, prevalence of tobacco smoking and its intensity according to the gender and age descriptions among the urban population in the Middle Volga region (Samara as an example city) is described in the article.
I.A. Agarkova, S.A. Babanov
doaj  

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

THE AGE FACTOR IN REGISTER-OF-MERIT JERSEYS [PDF]

open access: green, 1911
Edward N. Wentworth
openalex   +1 more source

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