Results 131 to 140 of about 26,929,049 (408)
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause+2 more
wiley +1 more source
FAKTOR-FAKTOR RISIKO TERJADINYA ASFIKSIA NEONATORUM DI RSD JOMBANG PERIODE 1 JANUARI - 31 DESEMBER 2007 [PDF]
Neonatal Asphyxia is an emergency condition when the baby failed to breath spontaneously and regularly after they were born. Neonatal asphyxia remains the main cause of neonatal mortality as well as permanent neurological abnormality.
SUNDARI TIKA, TRI
core
A case-control study of drug risk factors for age-related macular degeneration.
OBJECTIVE: To investigate the association between age-related macular degeneration (AMD) and exposure to antacids, antithyroids, thyroid hormones, and thiazide diuretics. DESIGN: Matched case-control study.
Chakravarthy, Usha+5 more
core +1 more source
Immunoregulatory mechanisms of the arachidonic acid pathway in cancer
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine+3 more
wiley +1 more source
Family stressors and children's outcomes [PDF]
The research reported here aimed to identify:1.which family stress factors and parental behaviours were associated with worse outcomes for children at age 7 andwhich factors helped children to succeed2.whether stressful life events experienced at ...
Gutman, Leslie+2 more
core
Modifiable risk factors associated with bronchiolitis [PDF]
Background: We sought to clarify possibly modifiable risk factors related to pollution responsible for acute bronchiolitis in hospitalized infants. Methods: For this observational study, we recruited 213 consecutive infants with bronchiolitis (cases ...
Alessandroni, Claudia+13 more
core +1 more source
The predictive value of the CONUT score combined with the A2DS2 scale for post-ischemic stroke infection [PDF]
Background/Aim. Stroke-associated infection is the most common and most serious complication of ischemic stroke (IS), which is the most important cause of death and disability in humans.
Zhang Yongqing, Zhang Wei, Zhou Yiwu
doaj +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Magneto-Convection and Lithium Age Estimates of the βPictoris Moving Group [PDF]
Although the means of the ages of stars in young groups determined from Li depletion often agree with mean ages determined from Hertzsprung - Russell diagram isochrones, there are often statistically significant differences in the ages of individual stars determined by the two methods.
arxiv +1 more source