Results 81 to 90 of about 2,699,032 (208)

Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts. [PDF]

, 2018
OBJECTIVES: To develop and validate a genetic tool to predict age of onset of aggressive prostate cancer (PCa) and to guide decisions of who to screen and at what age.

core   +2 more sources

Determinants of persistent asthma in young adults

European Clinical Respiratory Journal, 2018
Objective: The aim of the study was to evaluate determinants for the prognosis of asthma in a population-based cohort of young adults. Design: The study was a nine-year clinical follow up of 239 asthmatic subjects from an enriched population-based sample
Lisbet Krogh Traulsen, Anders Halling, Jesper Bælum, Jesper Rømhild Davidsen, Martin Miller, Øyvind Omland, David Sherson, Torben Sigsgaard, Trine Thilsing, Gert Thomsen, Lars Rauff Skadhauge   +10 more
doaj   +1 more source

PINK1 homozygous W437X mutation in a patient with apparent dominant transmission of parkinsonism. [PDF]

, 2006
We analyzed the PINK1 gene in 58 patients with early-onset Parkinsonism and detected the homozygous mutation W437X in 1 patient. The clinical phenotype was characterized by early onset (22 years of age), good re- sponse to levodopa, early fluctuations ...
CRISCUOLO C, DALLAPICCOLA B, DE MICHELE, GIUSEPPE, DE ROSA, ANNA, FILLA, ALESSANDRO, MANCINI P, MARONGIU R, SALVATORE, ELENA, VALENTE EM, VARRONE A, VOLPE G   +10 more
core  

Age of Onset of Schizophrenia [PDF]

British Journal of Psychiatry, 1988
S K, Jayaswal, , Adityanjee, S K, Khandelwal   +2 more
openaire   +2 more sources

Strong family history and early onset of schizophrenia: about 2 families in Northern Nigeria

The Pan African Medical Journal, 2016
Schizophrenia is a highly heritable psychotic disorder and high genetic loading is associated with early onset of the disease. The outcome of schizophrenia has also been linked with the age of onset as well as the presence of family history of the ...
Folorunsho Tajudeen Nuhu, Edwin Ehi Eseigbe, Baba Awoye Issa, Michael Omeiza Gomina   +3 more
doaj   +1 more source

Staphylococcal enterotoxin sensitization in a community-based population : a potential role in adult-onset asthma [PDF]

, 2014
Background: Recent studies suggest that Staphylococcus aureus enterotoxin sensitization is a risk factor for asthma. However, there is a paucity of epidemiologic evidence on adult-onset asthma in community-based populations.
Bachert, Claus, Chang, Yoon-Seok, Cho, Sang-Heon, Choi, Min-Ho, Kang, Hye-Ryun, Kim, Sae-Hoon, Lim, Min Kyung, Min, Kyung-Up, Park, Heung-Woo, Song, Woo-Jung, Tomassen, Peter, Yun, E Hwa   +11 more
core   +2 more sources

Clinical reasoning in canine spinal disease: what combination of clinical information is useful? [PDF]

, 2015
Spinal disease in dogs is commonly encountered in veterinary practice. Numerous diseases may cause similar clinical signs and presenting histories. The study objective was to use statistical models to identify combinations of discrete parameters from the
ABRAMSON, ARMAŞU, AWANO, BAGLEY, BESALTI, BRISSON, DA COSTA, DA COSTA, DA COSTA, DE DECKER, DE RISIO, DE RISIO, DE RISIO, DELAMAIDE GASPER, DRIVER, GANDINI, HOLDER, JEFFERY, JULL, KRANENBURG, LANE, LEVINE, LU, MAY, MCKEE, MEIJ, PALUS, PARENT, PARK, RUSBRIDGE, RUSBRIDGE, SCHMIDT, TABACHNICK, TIPOLD, TIPOLD, VAN WIE, ZENG   +36 more
core   +3 more sources

Peroxisome Proliferator-activated receptor alpha gene variation influences age of onset and progression of type 2 diabetes [PDF]

, 2005
Dysregulation of fatty acid metabolism is important in the pathogenesis of type 2 diabetes. Peroxisome proliferator-activated receptor (PPAR) is a master regulator of fatty acid catabolism, and PPAR activators delay the onset of type 2 diabetes.
Acharya, J., Flavell, D.M., Hawe, E., Humphries, S.E., Hurel, S.J., Ireland, H., Mather, H., Stephens, J.W.   +7 more
core  

Is the onset of disabling chronic conditions in later childhood associated with exposure to social disadvantage in earlier childhood? A prospective cohort study using the ONS Longitudinal Study for England and Wales [PDF]

, 2013
Background: The aetiology of disabling chronic conditions in childhood in high income countries is not fully understood, particularly the association with socio-economic status (SES).
Blackburn, Clare, Read, Janet, Spencer, Nick   +2 more
core   +1 more source

The duration of pubertal growth peak among three skeletal classes

Dental Press Journal of Orthodontics
Introduction: Pubertal growth peak is closely associated with a rapid increase in mandibular length and offers a wide range of therapeutic modifiability.
Waqar Jeelani, Mubassar Fida, Attiya Shaikh   +2 more
doaj   +1 more source