Results 101 to 110 of about 2,514,827 (314)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

A case involving a bovine aortic arch contributing to blunt thoracic aortic injury of triple rupture close to the pericardial reflection

Trauma Case Reports
A blunt thoracic aortic injury is a fatal condition that often requires emergency surgery. Although injuries to the aortic isthmus are common in trauma patients, the proximal aortic arch often remains intact.
Takuma Aoki, Hidetoshi Oka, Naohiko Oki, Hirofumi Kasahara   +3 more
doaj   +1 more source

Indigenous child safety [PDF]

Indigenous children are over represented in areas where child safety and security are compromised, argues this report. Summary National data show that Aboriginal and Torres Strait Islander children are over-represented in various aspects of child ...

core  

Suprascapular Nerve Block for Hemiplegic Shoulder Pain Post Stroke: Subgroup Analysis of Pain Response [PDF]

, 2015
This is an open access article. Open Access Journals by Jacobs Publishers is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.Background and Aims: Suprascapular nerve block is an effective intervention for hemiplegic ...
Adey-Wakeling, Zoe, Crotty, Maria, Liu, Enwu, Shanahan, Ernst Michael   +3 more
core  

Self-reported quality of care for older adults from 2004 to 2011: a cohort study [PDF]

, 2014
Background: little is known about changes in the quality of medical care for older adults over time. Objective: to assess changes in technical quality of care over 6 years, and associations with participants' characteristics.
Bachmann, Max O., Campbell, John L., Clark, Allan, Hardcastle, Antonia C., Henley, William E., Melzer, David, Mounce, Luke T. A., Richards, Suzanne H., Steel, Nick   +8 more
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Organization and support as an essential part of group exercise programs for older people with dementia: an end-user interview study

Frontiers in Sports and Active Living
IntroductionDevelopment of accessible group exercise sessions is warranted for home-dwelling older people with cognitive impairment or dementia. This study aims to explore the experiences of participants in a group exercise session organized with ...
Kristin Taraldsen, Arnhild J. Nygård, Elisabeth Boulton, Guro Grønningsæter, Marit H. Erland, Nina Waldenstrøm, Linda Johnsen, Gro G. Tangen, Gro G. Tangen, Randi Granbo   +9 more
doaj   +1 more source

Quality of life and socio-demographic factors associated with nutritional risk in Brazilian community-dwelling individuals aged 80 and over: cluster analysis and ensemble methods. [PDF]

Front Nutr, 2023
Brech GC, da Silva VC, Alonso AC, Machado-Lima A, da Silva DF, Micillo GP, Bastos MF, de Aquino RC.   +7 more
europepmc   +1 more source

Do Consultation Charges Deter General Practitioner Use Among Older People? A Natural Experiment. ESRI WP194. May 2007 [PDF]

, 2007
Background: A change in the pricing of general practitioner care in the Republic of Ireland in 2001 provides a natural experiment of the influence of economic incentives on GP visiting.
Layte, Richard, McGee, Hannah, O'Hanlon, Ann   +2 more
core   +1 more source

Causes of severe visual impairment and blindness in students in schools for the blind in Northwest Ethiopia. [PDF]

, 2017
OBJECTIVES: To determine the causes of severe visual impairment and blindness (SVI/BL) among students in schools for the blind in Northwest Ethiopia and to identify preventable and treatable causes.
Asferaw, Mulusew, Gilbert, Clare, Woodruff, Geoffrey   +2 more
core   +1 more source