Results 111 to 120 of about 2,555,271 (312)

Self-reported quality of care for older adults from 2004 to 2011: a cohort study [PDF]

, 2014
Background: little is known about changes in the quality of medical care for older adults over time. Objective: to assess changes in technical quality of care over 6 years, and associations with participants' characteristics.
Bachmann, Max O., Campbell, John L., Clark, Allan, Hardcastle, Antonia C., Henley, William E., Melzer, David, Mounce, Luke T. A., Richards, Suzanne H., Steel, Nick   +8 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Organization and support as an essential part of group exercise programs for older people with dementia: an end-user interview study

Frontiers in Sports and Active Living
IntroductionDevelopment of accessible group exercise sessions is warranted for home-dwelling older people with cognitive impairment or dementia. This study aims to explore the experiences of participants in a group exercise session organized with ...
Kristin Taraldsen, Arnhild J. Nygård, Elisabeth Boulton, Guro Grønningsæter, Marit H. Erland, Nina Waldenstrøm, Linda Johnsen, Gro G. Tangen, Gro G. Tangen, Randi Granbo   +9 more
doaj   +1 more source

Pensioner poverty over the next decade: what role for tax and benefit reform? [PDF]

, 2007
Recent falls in poverty amongst those aged 65 and over are unlikely to continue after 2007-08, even after the implementation of the proposals outlined in the Government's Pensions White Paper.
Brewer, M., Browne, J., Emmerson, C., Goodman, A., Muriel, A., Tetlow, G.   +5 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Analysis of Outcomes in Pancreaticoduodenectomy for Elderly Patients Aged 80 and Above: A Retrospective Study Using Inverse Probability of Treatment Weighting

Aging Medicine
Objectives With an aging population, more elderly individuals are facing the decision to undergo complex surgeries, such as pancreaticoduodenectomy (PD). This study evaluates the safety and feasibility of PD in patients aged 80 and above.
Tianxiao Wang, Yue Qiu, Yingjixing Luo, Ruili Wei, Li Xu, Jia Huang, Wenying Zhou, Hanchun Huang, Yongliang Sun, Zhiying Yang   +9 more
doaj   +1 more source

Quality of life and socio-demographic factors associated with nutritional risk in Brazilian community-dwelling individuals aged 80 and over: cluster analysis and ensemble methods. [PDF]

Front Nutr, 2023
Brech GC, da Silva VC, Alonso AC, Machado-Lima A, da Silva DF, Micillo GP, Bastos MF, de Aquino RC.   +7 more
europepmc   +1 more source

Do Consultation Charges Deter General Practitioner Use Among Older People? A Natural Experiment. ESRI WP194. May 2007 [PDF]

, 2007
Background: A change in the pricing of general practitioner care in the Republic of Ireland in 2001 provides a natural experiment of the influence of economic incentives on GP visiting.
Layte, Richard, McGee, Hannah, O'Hanlon, Ann   +2 more
core   +1 more source

Chemical characteristics of air from different source regions during the second Pacific Exploratory Mission in the Tropics (PEM-Tropics B) [PDF]

, 2001
Ten-day backward trajectories are used to determine the origins of air parcels arriving at locations of airborne DC-8 chemical measurements during NASA's second Pacific Exploratory Mission in the Tropics B that was conducted during February-April 1999 ...
Avery, MA, Blake, DR, Crawford, JH, Fuelberg, HE, Heikes, BG, Maloney, JC, Sachse, GW, Sandholm, ST, Singh, H, Talbot, RW   +9 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source