Results 111 to 120 of about 2,462,697 (323)
Quality of life and depression in elderly persons engaged in physical activities [PDF]
Vojnosanitetski Pregled, 2018 Backgroung/Aim. Since the number of elderly persons is gradually increasing worldwide, there is a need to identify the factors that affect the quality of healthy ageing. On the other hand, depression is the most common psychiatric disorder in the elderly
Trajkov Marija +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
Caring for a dying spouse at the end of life: 'It's one of the things you volunteer for when you get married': a qualitative study of the oldest carers' experiences. [PDF]
, 2016 older people aged 80 and over are increasingly providing end-of-life care to spouses at home and often do so for long periods of time, while also trying to manage their own illnesses and disabilities.
Carol Thomas +10 more
core +1 more source
Diagnosis and management of osteoporosis in the older senior
Clinical Interventions in Aging, 2009 Sheryl F Vondracek, Sunny A LinneburDepartment of Clinical Pharmacy, School of Pharmacy C238-L15, University of Colorado Denver, Aurora, CO, USAAbstract: The older senior is at high risk for osteoporosis.
Sheryl F Vondracek, Sunny A Linnebur
doaj
Revista Brasileira de OrtopediaObjective This study sought to analyze the relationship between the components and aggravations of body composition (obesity, sarcopenia, and sarcopenic obesity) and bone mineral density in elderly subjects aged ≥80 years.
Vanessa Ribeiro dos Santos +4 more
doaj +1 more source
Inception and deprescribing of statins in people aged over 80 years: cohort study [PDF]
Age and Ageing, 2017 statin use over the age of 80 years is weakly evidence-based. This study aimed to estimate rates of statin inception and deprescribing by frailty level in people aged 80 years or older.a cohort of 212,566 participants aged ≥80 years was sampled from the UK Clinical Practice Research Datalink. Statin inception was defined as a first-ever prescription in
Rathi Ravindrarajah +5 more
openaire +6 more sources
Molecular Oncology, EarlyView.Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan +10 more
wiley +1 more source
Colonic polyp histopathology and location in a community-based sample of older adults [PDF]
, 2016 BACKGROUND: Colorectal cancer and its precursors are highly prevalent in developed countries. Estimates in the available literature for prevalence of right-sided-only lesions vary between 20.5 and 48.1 %, with association with female gender and advancing
Ade Olomu +5 more
core +1 more source
Transcutaneous vagus nerve stimulation does not affect verbal memory performance in healthy volunteers [PDF]
, 2020 Introduction: Invasive vagus nerve stimulation (VNS) improves word recognition memory in patients with epilepsy. Recent studies with transcutaneous VNS (tVNS) have also shown positive effects on various subdomains of cognitive functioning in healthy ...
Boon, Paul +8 more
core +1 more source
Age and Ageing, 2013 BACKGROUND AND AIMS sarcopenia has been indicated as a reliable marker of frailty and poor prognosis among the oldest individuals. We evaluated the impact of sarcopenia on the risk of all-cause death in a population of frail older persons living in ...
F. Landi +8 more
semanticscholar +1 more source