Results 141 to 150 of about 1,192,855 (302)

Risk factors for postoperative pneumonia in older adults aged ≥ 80 years with gastric cancer

BMC Cancer
Background In Japan, the proportion of elderly gastric cancer patients is increasing. Although surgery in patients aged ≥ 80 years is relatively safe, postoperative pneumonia often occurs, reducing quality of life and being fatal.
Shunji Endo, Masaharu Higashida, Yoshinori Fujiwara, Kei Furuya, Shuya Yano, Toshimasa Okada, Kazuhiko Yoshimatsu, Tomio Ueno   +7 more
doaj   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Newly Diagnosed HIV in an Octogenarian Woman: A Case Report on Delayed Diagnosis in Vulnerable Populations

Clinical Case Reports
HIV infection in elderly individuals is often under recognized due to stigma, low clinical suspicion, and communication barriers. We present the case of an 85‐year‐old woman from a rural area who was diagnosed with HIV during staging workup for newly ...
HeeKyoung Choi, Myung Hee Chang, Heun Choi, Wooyong Jeong   +3 more
doaj   +1 more source

Outcomes of elderly patients aged 80 and over with symptomatic, severe aortic stenosis: impact of patient's choice of refusing aortic valve replacement on survival.

QJM : monthly journal of the Association of Physicians, 2008
P. Kojodjojo, N. Gohil, D. Barker, P. Youssefi, T. Salukhe, A. Choong, M. Koa‐Wing, J. Bayliss, D. Hackett, M. A. Khan   +9 more
semanticscholar   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

FEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang, Yuan Cao, Jing Du, Ying Zhang, Junxia Wang, Ying Yuan, Lianqing Sun   +6 more
wiley   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Factors associated with loneliness among individuals aged 80 years and over: Findings derived from the nationally representative "Old Age in Germany (D80+)" study.

Archives of gerontology and geriatrics (Print)
A. Hajek, R. Gyasi, Hans-Helmut König
semanticscholar   +1 more source

Anticholinergic Exposure in a Cohort of Adults Aged 80 years and Over

Basic & Clinical Pharmacology & Toxicology, 2017
Maarten Wauters, T. Klamer, M. Elseviers, B. Vaes, O. Dalleur, J. Degryse, Carlos E. Durán, T. Christiaens, M. Azermai, R. Vander Stichele   +9 more
semanticscholar   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

No clear relationship between antihypertensive class and cognitive function over 12 months in a cohort study of community-dwelling adults aged 80 and over. [PDF]

Ther Adv Chronic Dis, 2019
Peters R.
europepmc   +1 more source